Comparing the effect of hydroxyethyl starch 130/0.4 with balanced crystalloid solution on mortality and kidney failure in patients with severe sepsis (6S - Scandinavian Starch for Severe Sepsis/Septic Shock trial): Study protocol, design and rationale for a double-blinded, randomised clinical trial

Autor: Perner, Anders, Haase, Nicolai, Wetterslev, Jorn, Aneman, Anders, Tenhunen, Jyrki, Guttormsen, Anne Berit, Klemenzson, Gudmundur, Pott, Frank, Bodker, Karen Doris, Badstolokken, Per Martin, Bendtsen, Asger, Soe-Jensen, Peter, Tousi, Hamid, Bestle, Morten, Pawlowicz, Malgorzata, Winding, Robert, Bulow, Hans-Henrik, Kancir, Claude, Steensen, Morten, Nielsen, Jonas, Fogh, Bjarne, Madsen, Kristian R., Larsen, Nils H., Carlsson, Marcela, Wiis, Jorgen, Petersen, John Asger, Iversen, Susanne, Schoidt, Ole, Leivdal, Siv, Berezowicz, Pawel, Pettilä, Ville, Ruokonen, Esko, Klepstad, Pal, Karlsson, Sari, Kaukonen, Maija, Rutanen, Juha, Karason, Sigurbergur, Kjaelgaard, Anne Lene, Holst, Lars Brokso, Wernerman, Jan, Scandinavian Critical Care Trials

Publikováno v: Perner, A, Haase, N, Wetterslev, J, Aneman, A, Tenhunen, J, Guttormsen, A B, Klemenzson, G, Pott, F C, Bødker, K D, Bådstøløkken, P M, Bendtsen, A, Søe-Jensen, P, Tousi, H, Bestle, M H, Pawlowicz, M, Winding, R, Bülow, H-H, Kancir, C, Steensen, M, Nielsen, J T, Fogh, B, Madsen, K R, Larsen, N A G, Carlsson, M, Wiis, J, Petersen, J A, Iversen, S, Schøidt, O, Leivdal, S, Berezowicz, P, Pettilä, V, Ruokonen, E, Klepstad, P, Karlsson, S, Kaukonen, M, Rutanen, J, Karason, S, Kjældgaard, A L, Holst, L B, Wernerman, J & Scandinavian Critical Care Trials Group 2011, ' Comparing the effect of hydroxyethyl starch 130/0.4 with balanced crystalloid solution on mortality and kidney failure in patients with severe sepsis (6S--Scandinavian Starch for Severe Sepsis/Septic Shock trial): study protocol, design and rationale for a double-blinded, randomised clinical trial ', Trials, vol. 12, no. 1, pp. 24 . https://doi.org/10.1186/1745-6215-12-24
Trials, Vol 12, Iss 1, p 24 (2011)
Trials

Background By tradition colloid solutions have been used to obtain fast circulatory stabilisation in shock, but high molecular weight hydroxyethyl starch (HES) may cause acute kidney failure in patients with severe sepsis. Now lower molecular weight

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa817be3b36bef3101a71ca369933ee2
https://doi.org/10.1186/1745-6215-12-24