Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Bodil Øster"'
Autor:
Jesper Bertram Bramsen, Mads Heilskov Rasmussen, Halit Ongen, Trine Block Mattesen, Mai-Britt Worm Ørntoft, Sigrid Salling Árnadóttir, Juan Sandoval, Teresa Laguna, Søren Vang, Bodil Øster, Philippe Lamy, Mogens Rørbæk Madsen, Søren Laurberg, Manel Esteller, Emmanouil Theophilos Dermitzakis, Torben Falck Ørntoft, Claus Lindbjerg Andersen
Publikováno v:
Cell Reports, Vol 19, Iss 6, Pp 1268-1280 (2017)
Colorectal cancer (CRC) is characterized by major inter-tumor diversity that complicates the prediction of disease and treatment outcomes. Recent efforts help resolve this by sub-classification of CRC into natural molecular subtypes; however, this st
Externí odkaz:
https://doaj.org/article/ad1da5ab834241b095d81266d558be90
Functional screening identifies miRNAs influencing apoptosis and proliferation in colorectal cancer.
Autor:
Lise Lotte Christensen, Anja Holm, Juha Rantala, Olli Kallioniemi, Mads H Rasmussen, Marie S Ostenfeld, Frederik Dagnaes-Hansen, Bodil Øster, Troels Schepeler, Heidi Tobiasen, Kasper Thorsen, Oliver M Sieber, Peter Gibbs, Philippe Lamy, Torben F Hansen, Anders Jakobsen, Eva M Riising, Kristian Helin, Jan Lubinski, Rikke Hagemann-Madsen, Søren Laurberg, Torben F Ørntoft, Claus L Andersen
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e96767 (2014)
MicroRNAs (miRNAs) play a critical role in many biological processes and are aberrantly expressed in human cancers. Particular miRNAs function either as tumor suppressors or oncogenes and appear to have diagnostic and prognostic significance. Althoug
Externí odkaz:
https://doaj.org/article/22ba41fcd8b3409d804194563757951f
Autor:
Emil Kofod-Olsen, Janni M L Møller, Mariane H Schleimann, Bettina Bundgaard, Rasmus O Bak, Bodil Øster, Jacob G Mikkelsen, Ted Hupp, Per Höllsberg
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59223 (2013)
Infection with human herpesvirus (HHV)-6B alters cell cycle progression and stabilizes tumor suppressor protein p53. In this study, we have analyzed the activity of p53 after stimulation with p53-dependent and -independent DNA damaging agents during
Externí odkaz:
https://doaj.org/article/47cab761a6914845b4a9830b3b2071cd
Autor:
Karin Birkenkamp-Demtröder, Stephan A Hahn, Francisco Mansilla, Kasper Thorsen, Abdelouahid Maghnouj, Rikke Christensen, Bodil Øster, Torben Falck Ørntoft
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73593 (2013)
Keratin 23 (KRT23) is strongly expressed in colon adenocarcinomas but absent in normal colon mucosa. Array based methylation profiling of 40 colon samples showed that the promoter of KRT23 was methylated in normal colon mucosa, while hypomethylated i
Externí odkaz:
https://doaj.org/article/0d933cb775604d5aa5d1b7c8dc98ad98
Autor:
Lisa Scheiblecker, Natalia Marek-Trzonkowska, Marcos Yebenes Mayordomo, Ted R. Hupp, J. Robert O’Neill, Małgorzata Kurkowiak, Bodil Øster, Małgorzata Winniczuk, Ali Al-Saadi, Borek Vojtesek, Giuseppa Grasso, Jakub Faktor
Publikováno v:
RNA Biology. 18:2556-2575
RNA variants that emerge from editing and alternative splicing form important regulatory stages in protein signalling. In this report, we apply an integrated DNA and RNA variant detection workbench to define the range of RNA variants that deviate fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::996189641794d1058642f50d17a0d93e
https://doi.org/10.1080/15476286.2021.1932345
https://doi.org/10.1080/15476286.2021.1932345
Autor:
Halit Ongen, Philippe Lamy, Teresa Laguna, Emmanouil T. Dermitzakis, Jesper B. Bramsen, Søren Vang, Juan Sandoval, Mogens Madsen, Søren Laurberg, Mads Rasmussen, Claus L. Andersen, Sigrid S. Árnadóttir, Manel Esteller, Bodil Øster, Trine B. Mattesen, Mai-Britt Worm Ørntoft, Torben F. Ørntoft
Publikováno v:
Cell Reports, Vol. 19, No 6 (2017) pp. 1268-1280
Cell Reports, Vol 19, Iss 6, Pp 1268-1280 (2017)
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Bramsen, J B, Rasmussen, M H, Ongen, H, Mattesen, T B, Ørntoft, M-B W, Árnadóttir, S S, Sandoval, J, Laguna, T, Vang, S, Øster, B, Lamy, P, Madsen, M R, Laurberg, S, Esteller, M, Dermitzakis, E T, Ørntoft, T F & Andersen, C L 2017, ' Molecular-Subtype-Specific Biomarkers Improve Prediction of Prognosis in Colorectal Cancer ', Cell Reports, vol. 19, no. 6, pp. 1268-1280 . https://doi.org/10.1016/j.celrep.2017.04.045
Cell Reports, Vol 19, Iss 6, Pp 1268-1280 (2017)
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Bramsen, J B, Rasmussen, M H, Ongen, H, Mattesen, T B, Ørntoft, M-B W, Árnadóttir, S S, Sandoval, J, Laguna, T, Vang, S, Øster, B, Lamy, P, Madsen, M R, Laurberg, S, Esteller, M, Dermitzakis, E T, Ørntoft, T F & Andersen, C L 2017, ' Molecular-Subtype-Specific Biomarkers Improve Prediction of Prognosis in Colorectal Cancer ', Cell Reports, vol. 19, no. 6, pp. 1268-1280 . https://doi.org/10.1016/j.celrep.2017.04.045
Colorectal cancer (CRC) is characterized by major inter-tumor diversity that complicates the prediction of disease and treatment outcomes. Recent efforts help resolve this by sub-classification of CRC into natural molecular subtypes; however, this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0944c440068e8ed95ba41b9af5a2fd
https://archive-ouverte.unige.ch/unige:112673
https://archive-ouverte.unige.ch/unige:112673
Autor:
Mads Rasmussen, Emmanouil T. Dermitzakis, Nicola Whiffin, Jesper B. Bramsen, Richard S. Houlston, Juan Sandoval, Deborah Bielser, Torben F. Ørntoft, Manel Esteller, Luciana Romano, Enrique Vidal, Pedro G. Ferreira, Ian Tomlinson, Claus L. Andersen, Halit Ongen, Alexandra Planchon, Ismael Padioleau, Bodil Øster
Publikováno v:
Nature
Nature, Vol. 512, No 7512 (2014) pp. 87-90
Ongen, H, Andersen, C L, Bramsen, J B, Oster, B, Rasmussen, M H, Ferreira, P G, Sandoval, J, Vidal, E, Whiffin, N, Planchon, A, Padioleau, I, Bielser, D, Romano, L, Tomlinson, I, Houlston, R S, Esteller, M, Orntoft, T F & Dermitzakis, E T 2014, ' Putative cis-regulatory drivers in colorectal cancer ', Nature, vol. 512, no. 7512, pp. 87-90 . https://doi.org/10.1038/nature13602
Nature, Vol. 512, No 7512 (2014) pp. 87-90
Ongen, H, Andersen, C L, Bramsen, J B, Oster, B, Rasmussen, M H, Ferreira, P G, Sandoval, J, Vidal, E, Whiffin, N, Planchon, A, Padioleau, I, Bielser, D, Romano, L, Tomlinson, I, Houlston, R S, Esteller, M, Orntoft, T F & Dermitzakis, E T 2014, ' Putative cis-regulatory drivers in colorectal cancer ', Nature, vol. 512, no. 7512, pp. 87-90 . https://doi.org/10.1038/nature13602
The cis-regulatory effects responsible for cancer development have not been as extensively studied as the perturbations of the protein coding genome in tumorigenesis. To better characterize colorectal cancer (CRC) development we conducted an RNA-sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335f08ce88741fa5205da18827e1313e
Autor:
Lise Lotte Christensen, Kristian Q Hansen, Mads Rasmussen, Rikke Hagemann-Madsen, Kasper Thorsen, Peter Gibbs, Bodil Øster, Philippe Lamy, Claus L. Andersen, Marie Stampe Ostenfeld, Søren Laurberg, Kristina Byskov, Troels Schepeler, Karin Birkenkamp-Demtroeder, Anja Holm, Oliver M. Sieber, Heidi Tobiasen, Jan Lubinski, Torben F. Ørntoft
Publikováno v:
International Journal of Cancer. 133:67-78
Colorectal cancer (CRC) is one of the leading causes of cancer deaths in Western countries. A significant number of CRC patients undergoing curatively intended surgery subsequently develop recurrence and die from the disease. MicroRNAs (miRNAs) are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e3bc062c8a75966cf856cce019bad01
https://doi.org/10.1002/ijc.28010
https://doi.org/10.1002/ijc.28010
Autor:
Anthony R. Dallosso, C Owen, Thomas J. Curry, Anne L. Hancock, Kasper Thorsen, Alexander Greenhough, Claus L. Andersen, Karim Malik, Bodil Øster, Christos Paraskeva, M Frank, Marianna Szemes
Publikováno v:
Dallosso, A R, Øster, B, Greenhough, A, Thorsen, K, Curry, T J, Owen, C, Hancock, A L, Szemes, M, Paraskeva, C, Frank, M, Andersen, C L & Malik, K 2012, ' Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways ', Oncogene, no. 31, pp. 4409-4419 . https://doi.org/10.1038/onc.2011.609
Loss of tumour suppressor gene function can occur as a result of epigenetic silencing of large chromosomal regions, referred to as long-range epigenetic silencing (LRES), and genome-wide analyses have revealed that LRES is present in many cancer type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad58dc41622b944e03c13e76f97fdc04
https://doi.org/10.1038/onc.2011.609
https://doi.org/10.1038/onc.2011.609
Autor:
Kasper Thorsen, Bodil Øster, Karin Birkenkamp-Demtröder, Abdelouahid Maghnouj, Claus L. Andersen, Stephan A. Hahn, Francisco Mansilla, Torben F. Ørntoft
Publikováno v:
British Journal of Cancer
Background: The KIAA1199 transcript is upregulated in colon adenomas and downregulated upon β-catenin knockdown. Methods: Transcript profiling was performed on >500 colon biopsies, methylation profiling data were compared with transcript data. Immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7375b9e84c2edf22c04c50c08f5a93e5
https://doi.org/10.1038/bjc.2011.268
https://doi.org/10.1038/bjc.2011.268