IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints

Autor: Panda, Sudeepta Kumar, Wigerblad, Gustaf, Jiang, Long, Jiménez-Andrade, Yanek, Iyer, Vaishnavi Srinivasan, Shen, Yunbing, Boddul, Sanjaykumar V., Guerreiro-Cacais, André Ortlieb, Raposo, Bruno, Kasza, Zsolt, Wermeling, Fredrik

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2020 Feb 01. 117(6), 3103-3113.

Externí odkaz: https://www.jstor.org/stable/26928758

Designing custom CRISPR libraries for hypothesis-driven drug target discovery

Autor: Iyer, Vaishnavi Srinivasan, Jiang, Long, Shen, Yunbing, Boddul, Sanjaykumar V., Panda, Sudeepta Kumar, Kasza, Zsolt, Schmierer, Bernhard, Wermeling, Fredrik

Publikováno v: In Computational and Structural Biotechnology Journal 2020 18:2237-2246

CRISPR/Cas9-induced DNA damage enriches for mutations in a p53-linked interactome: implications for CRISPR-based therapies

Autor: Jiang, Long, Ingelshed, Katrine, Shen, Yunbing, Boddul, Sanjaykumar V., Iyer, Vaishnavi Srinivasan, Kasza, Zsolt, Sedimbi, Saikiran, Lane, David P., Wermeling, Fredrik

Inactivating p53 mutations are the most abundant genetic alterations found in cancer. Here we show that CRISPR/Cas9-induced double-stranded DNA breaks enrich for cells deficient in p53 and in genes of a core CRISPR-p53 tumor suppressor interactome. S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1392::e70c70916e6e30e697e19acb89f1bf35
https://hdl.handle.net/10356/163561

IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints

Autor: Panda, Sudeepta Kumar, Wigerblad, Gustaf, Jiang, Long, Jiménez-Andrade, Yanek, Iyer, Vaishnavi Srinivasan, Shen, Yunbing, Boddul, Sanjaykumar V., Guerreiro-Cacais, André Ortlieb, Raposo, Bruno, Kasza, Zsolt, Wermeling, Fredrik

Publikováno v: Proceedings of the National Academy of Sciences. 117(6):3103-3113

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=sygma_______::f268a08aea8bbaa7d61d168691a8f404

In vitro and ex vivo functional characterization of human HLA-DRB1∗04 restricted T cell receptors.

Autor: Boddul SV; Division of Rheumatology, Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden., Sharma RK; Division of Rheumatology, Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden., Dubnovitsky A; Division of Rheumatology, Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden.; Science for Life Laboratory, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Raposo B; Division of Rheumatology, Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden., Gerstner C; Division of Rheumatology, Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden., Shen Y; Division of Rheumatology, Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden., Iyer VS; Division of Rheumatology, Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden.; School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore., Kasza Z; Division of Rheumatology, Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden., Kwok WW; Translational Research Program, BRI at Virginia Mason, Seattle, WA, USA., Winkler AR; Department of Inflammation and Immunology, Pfizer Inc., Cambridge, MA, USA., Klareskog L; Division of Rheumatology, Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden., Malmström V; Division of Rheumatology, Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden., Bettini M; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, UT, USA., Wermeling F; Division of Rheumatology, Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden.

Publikováno v: Journal of translational autoimmunity [J Transl Autoimmun] 2021 Mar 03; Vol. 4, pp. 100087. Date of Electronic Publication: 2021 Mar 03 (Print Publication: 2021).