Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Bochuan Teng"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Ammonium (NH4 +), a breakdown product of amino acids that can be toxic at high levels, is detected by taste systems of organisms ranging from C. elegans to humans and has been used for decades in vertebrate taste research. Here we report tha
Externí odkaz:
https://doaj.org/article/6ab765a9f1fd4444b3e328b0c264e04f
Autor:
Bochuan Teng, Joshua P Kaplan, Ziyu Liang, Kevin Saejin Chyung, Marcel P Goldschen-Ohm, Emily R Liman
Publikováno v:
eLife, Vol 12 (2023)
Otopetrin proteins (OTOPs) form proton-selective ion channels that are expressed in diverse cell types where they mediate detection of acids or regulation of pH. In vertebrates there are three family members: OTOP1 is required for formation of otocon
Externí odkaz:
https://doaj.org/article/c7815c801b674f2db99568a4fe6ca88e
Autor:
Bochuan Teng, Joshua P Kaplan, Ziyu Liang, Zachary Krieger, Yu-Hsiang Tu, Batuujin Burendei, Andrew B Ward, Emily R Liman
Publikováno v:
eLife, Vol 11 (2022)
Otopetrin (OTOP) channels are proton-selective ion channels conserved among vertebrates and invertebrates, with no structural similarity to other ion channels. There are three vertebrate OTOP channels (OTOP1, OTOP2, and OTOP3), of which one (OTOP1) f
Externí odkaz:
https://doaj.org/article/79614696f9514368bdf4b9e88dbde71d
Autor:
Joshua P Kaplan, Bochuan Teng, Ziyu Liang, Kevin Saejin Chyung, Marcel P Goldschen-Ohm, Emily R Liman
Publikováno v:
eLife. 12
Otopetrin proteins (OTOPs) form proton-selective ion channels that are expressed in diverse cell types where they mediate detection of acids or regulation of pH. In vertebrates there are three family members: OTOP1 is required for formation of otocon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58de3670a168928e7ba21094a67b8d54
https://doi.org/10.7554/elife.85317
https://doi.org/10.7554/elife.85317
Otopetrin proteins (OTOPs) form proton-selective ion channels that are expressed in diverse cell types where they may mediate detection of acids or regulation of pH. In vertebrates there are three family members: OTOP1 is required for formation of ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0094d83b192ca3e3edc56b5f2f588b86
https://doi.org/10.1101/2022.12.15.520539
https://doi.org/10.1101/2022.12.15.520539
Autor:
Joshua P Kaplan, Bochuan Teng, Ziyu Liang, Zachary Krieger, Yu-Hsiang Tu, Batuujin Burendei, Andrew B Ward, Emily R Liman
Publikováno v:
eLife. 11
Otopetrin (OTOP) channels are proton-selective ion channels conserved among vertebrates and invertebrates, with no structural similarity to other ion channels. There are three vertebrate OTOP channels (OTOP1, OTOP2, and OTOP3), of which one (OTOP1) f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e98f13213b32b2200f46a029ec1c98
https://pubmed.ncbi.nlm.nih.gov/35920807
https://pubmed.ncbi.nlm.nih.gov/35920807
Publikováno v:
Biophysical Journal. 122:396a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87d2aeb6b378cfdc609d5662514e4b8f
https://doi.org/10.1016/j.bpj.2022.11.2160
https://doi.org/10.1016/j.bpj.2022.11.2160
Autor:
Bochuan Teng, Joshua P Kaplan, Wen-Hsin Lee, Mark S.P. Sansom, Yu-Hsiang Tu, Andrew B. Ward, Emily R. Liman, Che Chun Alex Tsui, Kei Saotome
Publikováno v:
Nature structural & molecular biology
Otopetrins (Otop1–Otop3) comprise one of two known eukaryotic proton-selective channel families. Otop1 is required for otoconia formation and a candidate mammalian sour taste receptor. Here we report cryo-EM structures of zebrafish Otop1 and chicke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6052babc2b89e9a3303be75ece3e90
https://doi.org/10.1038/s41594-019-0235-9
https://doi.org/10.1038/s41594-019-0235-9