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Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

Autor: Milne RL; Cancer Epidemiology and Intelligence Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Kuchenbaecker KB; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Michailidou K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Electron Microscopy/Molecular Pathology, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus., Beesley J; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Kar S; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Lindström S; Department of Epidemiology, University of Washington School of Public Health, Seattle, Washington, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Hui S; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada., Lemaçon A; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada., Soucy P; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Jiang X; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Rostamianfar A; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada., Finucane H; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Aalfs CM; Department of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands., Adams M; Center for Inherited Disease Research (CIDR), Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Adlard J; Yorkshire Regional Genetics Service, Chapel Allerton Hospital, Leeds, UK., Agata S; Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto (IOV), IRCCS, Padua, Italy., Ahmed S; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Ahsan H; Center for Cancer Epidemiology and Prevention, University of Chicago, Chicago, Illinois, USA., Aittomäki K; Department of Clinical Genetics, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Al-Ejeh F; Personalised Medicine Team, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Allen J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Ambrosone CB; Roswell Park Cancer Institute, Buffalo, New York, USA., Amos CI; Center for Genomic Medicine, Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, Lebanon, New Hampshire, USA., Andrulis IL; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Anton-Culver H; Department of Epidemiology, University of California, Irvine, Irvine, California, USA., Antonenkova NN; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus., Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany., Arnold N; Institute of Clinical Molecular Biology / Department of Gynecology and Obstetrics, University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany., Aronson KJ; Department of Public Health Sciences and Cancer Research Institute, Queen's University, Kingston, Ontario, Canada., Auber B; Institute of Human Genetics, Hannover Medical School, Hannover, Germany., Auer PL; Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA., Ausems MGEM; Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands., Azzollini J; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Istituto Nazionale dei Tumori (INT), Milan, Italy., Bacot F; McGill University and Génome Québec Innovation Centre, Montréal, Québec, Canada., Balmaña J; Department of Medical Oncology, University Hospital, Vall d'Hebron, Barcelona, Spain., Barile M; Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, Milan, Italy., Barjhoux L; Bâtiment Cheney D, Centre Léon Bérard, Lyon, France., Barkardottir RB; Laboratory of Cell Biology, Department of Pathology, Landspitali, Reykjavik, Iceland.; BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Barrdahl M; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Barnes D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Barrowdale D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Baynes C; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Beckmann MW; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany., Benitez J; Human Genotyping Unit -Centro Nacional de Genotipado (CEGEN), Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.; Human Genetics Group, Human Cancer Genetics Programme, Spanish National Cancer Centre (CNIO), Madrid, Spain.; Spanish Network on Rare Diseases (CIBERER), Madrid, Spain., Bermisheva M; Institute of Biochemistry and Genetics, Ufa Scientific Center of the Russian Academy of Sciences, Ufa, Russian Federation., Bernstein L; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, USA., Bignon YJ; Université Clermont Auvergne, INSERM, U1240, Imagerie Moléculaire et Stratégies Théranostiques, Centre Jean Perrin, Clermont-Ferrand, France., Blazer KR; Clinical Cancer Genetics, City of Hope, Duarte, California, USA., Blok MJ; Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands., Blomqvist C; Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Blot W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; International Epidemiology Institute, Rockville, Maryland, USA., Bobolis K; City of Hope Clinical Cancer Genomics Community Research Network, Duarte, California, USA., Boeckx B; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Leuven, Belgium., Bogdanova NV; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus.; Department of Radiation Oncology, Hannover Medical School, Hannover, Germany.; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Bojesen A; Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark., Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bonanni B; Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, Milan, Italy., Børresen-Dale AL; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway., Bozsik A; Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary., Bradbury AR; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Brand JS; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Brauch H; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; University of Tübingen, Tübingen, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany., Bressac-de Paillerets B; Gustave Roussy, Biopathology Department, Villejuif, France., Brewer C; Department of Clinical Genetics, Royal Devon and Exeter Hospital, Exeter, UK., Brinton L; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA., Broberg P; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden., Brooks-Wilson A; Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia, Canada., Brunet J; Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI (Institut d'Investigació Biomèdica de Girona), Catalan Institute of Oncology, Girona, Spain., Brüning T; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), Bochum, Germany., Burwinkel B; Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany.; Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany., Buys SS; Department of Medicine, Huntsman Cancer Institute, Salt Lake City, Utah, USA., Byun J; Center for Genomic Medicine, Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, Lebanon, New Hampshire, USA., Cai Q; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Caldés T; Medical Oncology Department, CIBERONC, Hospital Clínico San Carlos, Madrid, Spain., Caligo MA; Section of Molecular Genetics, Department of Laboratory Medicine, University of Pisa and University Hospital of Pisa, Pisa, Italy., Campbell I; Research Department, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia., Canzian F; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany., Caron O; Gustave Roussy, Biopathology Department, Villejuif, France., Carracedo A; Genomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, Servizo Galego de Saúde SERGAS, Santiago de Compostela, Spain.; Centro de Investigación en Red de Enfermedades Raras (CIBERER) and Centro Nacional de Genotipado (CEGEN-PRB2), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Carter BD; Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA., Castelao JE; Oncology and Genetics Unit, Instituto de Investigación Biomédica (IBI) de Orense-Pontevedra-Vigo, Xerencia de Xestión Integrada de Vigo, Servizo Galego de Saúde SERGAS, Vigo, Spain., Castera L; Centre François Baclesse, Caen, France., Caux-Moncoutier V; Service de Génétique Oncologique and INSERM U830, Institut Curie, Paris, France - Université Paris Descartes, Sorbonne Paris Cité., Chan SB, Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA., Chen X; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Cheng TD; Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York, USA., Chiquette J; Unité de Recherche en Santé des Populations, Centre des Maladies du Sein Deschênes-Fabia, Hôpital du Saint-Sacrement, Québec City, Québec, Canada., Christiansen H; Department of Radiation Oncology, Hannover Medical School, Hannover, Germany., Claes KBM; Center for Medical Genetics, Ghent University, Ghent, Belgium., Clarke CL; Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia., Conner T; Huntsman Cancer Institute, Salt Lake City, Utah, USA., Conroy DM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Cook J; Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield, UK., Cordina-Duverger E; Cancer and Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France., Cornelissen S; Division of Molecular Pathology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Coupier I; Unité d'Oncogénétique, CHU Arnaud de Villeneuve, Montpellier, France., Cox A; Academic Unit of Molecular Oncology, Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK., Cox DG; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; INSERM U1052, Cancer Research Center of Lyon, Lyon, France., Cross SS; Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, UK., Cuk K; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany., Cunningham JM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA., Damiola F; Bâtiment Cheney D, Centre Léon Bérard, Lyon, France., Darabi H; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Davidson R; Department of Clinical Genetics, South Glasgow University Hospitals, Glasgow, UK., De Leeneer K; Center for Medical Genetics, Ghent University, Ghent, Belgium., Devilee P; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Dicks E; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Diez O; Oncogenetics Group, Vall d'Hebron Institute of Oncology (VHIO), Clinical and Molecular Genetics Area, Vall d'Hebron University Hospital, Barcelona, Spain., Ding YC; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, USA., Ditsch N; Department of Gynecology and Obstetrics, Ludwig Maximilians University of Munich, Munich, Germany., Doheny KF; Center for Inherited Disease Research (CIDR), Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Domchek SM; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Dorfling CM; Cancer Genetics Laboratory, Department of Genetics, University of Pretoria, Arcadia, South Africa., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Dos-Santos-Silva I; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK., Dubois S; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada., Dugué PA; Cancer Epidemiology and Intelligence Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Dumont M; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Durcan L; Southampton Clinical Trials Unit, Faculty of Medicine, University of Southampton, Southampton, UK.; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Dwek M; Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, UK., Dworniczak B; Institute of Human Genetics, University of Münster, Münster, Germany., Eccles D; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Eeles R; Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK., Ehrencrona H; Department of Clinical Genetics, Lund University Hospital, Lund, Sweden., Eilber U; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Ejlertsen B; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Ekici AB; Institute of Human Genetics, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany., Eliassen AH; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Engel C; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE-Leipzig Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany., Eriksson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Fachal L; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Faivre L; Genetics Department, Dijon University Hospital, Dijon, France.; Oncogenetics, Centre Georges-François Leclerc, Dijon, France., Fasching PA; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany.; Division of Hematology and Oncology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA., Faust U; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Figueroa J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.; Usher Institute of Population Health Sciences and Informatics, CRUK Edinburgh Centre, University of Edinburgh Medical School, Edinburgh, UK., Flesch-Janys D; Institute for Medical Biometrics and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Cancer Epidemiology, Clinical Cancer Registry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Fletcher O; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Flyger H; Department of Breast Surgery, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Foulkes WD; Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montréal, Québec, Canada., Friedman E; Susanne Levy Gertner Oncogenetics Unit, Institute of Human Genetics, Chaim Sheba Medical Center, Ramat Gan, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel., Fritschi L; School of Public Health, Curtin University, Perth, Western Australia, Australia., Frost D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Gabrielson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Gaddam P; Clinical Cancer Genetics Laboratory, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Gammon MD; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Ganz PA; Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center, Schools of Medicine and Public Health, University of California, Los Angeles, Los Angeles, California, USA., Gapstur SM; Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA., Garber J; Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Garcia-Barberan V; Medical Oncology Department, CIBERONC, Hospital Clínico San Carlos, Madrid, Spain., García-Sáenz JA; Medical Oncology Department, CIBERONC, Hospital Clínico San Carlos, Madrid, Spain., Gaudet MM; Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA., Gauthier-Villars M; Service de Génétique Oncologique and INSERM U830, Institut Curie, Paris, France - Université Paris Descartes, Sorbonne Paris Cité., Gehrig A; Centre of Familial Breast and Ovarian Cancer, Department of Medical Genetics, Institute of Human Genetics, University Würzburg, Würzburg, Germany., Georgoulias V; Department of Medical Oncology, University Hospital of Heraklion, Heraklion, Greece., Gerdes AM; Department of Clinical Genetics, Rigshospitalet, Copenhagen, Denmark., Giles GG; Cancer Epidemiology and Intelligence Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Glendon G; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada., Godwin AK; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA., Goldberg MS; Department of Medicine, McGill University, Montréal, Québec, Canada.; Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montréal, Québec, Canada., Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA., González-Neira A; Human Genotyping Unit -Centro Nacional de Genotipado (CEGEN), Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Goodfellow P; Department of Obstetrics and Gynecology, Ohio State University James Comprehensive Cancer Center, Columbus, Ohio, USA., Greene MH; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA., Alnæs GIG; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway., Grip M; Department of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland., Gronwald J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Grundy A; Centre de Recherche du Centre Hospitalier de Université de Montréal (CHUM), Montréal, Québec, Canada., Gschwantler-Kaulich D; Department of Obstetrics and Gynaecology and Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria., Guénel P; Cancer and Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France., Guo Q; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Haeberle L; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany., Hahnen E; Center for Familial Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Håkansson N; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Hallberg E; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Hamel N; McGill University and Génome Québec Innovation Centre, Montréal, Québec, Canada., Hankinson S; Department of Biostatistics and Epidemiology, University of Massachusetts, Amherst, Amherst, Massachusetts, USA., Hansen TVO; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Harrington P; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Hart SN; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Hartikainen JM; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland., Healey CS; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Hein A; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany., Helbig S; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Henderson A; Institute of Genetic Medicine, Centre for Life, Newcastle-upon-Tyne Hospitals NHS Trust, Newcastle-upon-Tyne, UK., Heyworth J; School of Population Health, University of Western Australia, Perth, Western Australia, Australia., Hicks B; Cancer Genomics Research Laboratory (CGR), Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Hillemanns P; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Hodgson S; Medical Genetics Unit, St George's, University of London, London, UK., Hogervorst FB; Family Cancer Clinic, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Hollestelle A; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Hooning MJ; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Hoover B; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Hu C; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Huang G; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Hulick PJ; Center for Medical Genetics, NorthShore University HealthSystem, Evanston, Illinois, USA.; Pritzker School of Medicine, University of Chicago, Evanston, Illinois, USA., Humphreys K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Hunter DJ; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Imyanitov EN; N.N. Petrov Institute of Oncology, St. Petersburg, Russian Federation., Isaacs C; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Iwasaki M; Division of Epidemiology, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan., Izatt L; Clinical Genetics, Guy's and St Thomas' NHS Foundation Trust, London, UK., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., James P; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia.; Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Janavicius R; State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania., Janni W; Department of Gynaecology and Obstetrics, University of Ulm, Ulm, Germany., Jensen UB; Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark., John EM; Department of Epidemiology, Cancer Prevention Institute of California, Fremont, California, USA.; Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California, USA., Johnson N; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Jones K; Cancer Genomics Research Laboratory (CGR), Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Jones M; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Jukkola-Vuorinen A; Department of Oncology, Oulu University Hospital, University of Oulu, Oulu, Finland., Kaaks R; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Kabisch M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Kaczmarek K; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Kang D; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea., Kast K; Department of Gynecology and Obstetrics, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Keeman R; Division of Molecular Pathology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Kerin MJ; School of Medicine, National University of Ireland, Galway, Ireland., Kets CM; Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands., Keupers M; Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Khan S; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Khusnutdinova E; Institute of Biochemistry and Genetics, Ufa Scientific Center of the Russian Academy of Sciences, Ufa, Russian Federation.; Department of Genetics and Fundamental Medicine, Bashkir State University, Ufa, Russian Federation., Kiiski JI; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Kim SW; Department of Obstetrics and Gynaecology and Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria., Knight JA; Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.; Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada., Konstantopoulou I; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece., Kosma VM; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland., Kristensen VN; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Clinical Molecular Biology, Oslo University Hospital, University of Oslo, Oslo, Norway., Kruse TA; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark., Kwong A; Hong Kong Hereditary Breast Cancer Family Registry, Hong Kong.; Department of Surgery, University of Hong Kong, Hong Kong.; Department of Surgery, Hong Kong Sanatorium and Hospital, Hong Kong., Lænkholm AV; Department of Pathology, University Hospital of Region Zealand, Division Slagelse, Slagelse, Denmark., Laitman Y; Susanne Levy Gertner Oncogenetics Unit, Institute of Human Genetics, Chaim Sheba Medical Center, Ramat Gan, Israel., Lalloo F; Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK., Lambrechts D; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Leuven, Belgium., Landsman K; Clalit National Cancer Control Center, Haifa, Israel., Lasset C; Unité de Prévention et d'Epidémiologie Génétique, Centre Léon Bérard, Lyon, France., Lazaro C; Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, Barcelona, Spain., Le Marchand L; University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Lecarpentier J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Lee A; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Lee E; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Lee JW; Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Republic of Korea., Lee MH; Department of Surgery, Soonchunhyang University and Hospital, Seoul, Republic of Korea., Lejbkowicz F; Clalit National Cancer Control Center, Haifa, Israel., Lesueur F; Institut Curie, Paris, France.; PSL Research University, Paris, France.; INSERM U900, Paris, France.; Mines Paris Tech, Fontainebleau, France., Li J; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Lilyquist J; Department of Health Sciences Research, Mayo Clinic, Scottsdale, Arizona, USA., Lincoln A; Clinical Genetics Research Laboratory, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Lissowska J; Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland., Lo WY; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; University of Tübingen, Tübingen, Germany., Loibl S; German Breast Group, Neu Isenburg, Germany., Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Loud JT; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA., Lubinski J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Luccarini C; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Lush M; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., MacInnis RJ; Cancer Epidemiology and Intelligence Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Maishman T; Southampton Clinical Trials Unit, Faculty of Medicine, University of Southampton, Southampton, UK.; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Makalic E; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Kostovska IM; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', Macedonian Academy of Sciences and Arts, Skopje, Macedonia., Malone KE; Division of Public Health Sciences, Epidemiology Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Manoukian S; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Istituto Nazionale dei Tumori (INT), Milan, Italy., Manson JE; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Margolin S; Department of Oncology, Pathology, Karolinska Institutet, Stockholm, Sweden., Martens JWM; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Martinez ME; Moores Cancer Center, University of California, San Diego, La Jolla, California, USA.; Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, California, USA., Matsuo K; Division of Molecular and Clinical Epidemiology, Aichi Cancer Center Research Institute, Nagoya, Japan.; Department of Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Mavroudis D; Department of Medical Oncology, University Hospital of Heraklion, Heraklion, Greece., Mazoyer S; Lyon Neuroscience Research Center-CRNL, INSERM U1028, CNRS UMR 5292, University of Lyon, Lyon, France., McLean C; Anatomical Pathology, Alfred Hospital, Melbourne, Victoria, Australia., Meijers-Heijboer H; Department of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands.; Department of Clinical Genetics, VU University Medical Centre, Amsterdam, the Netherlands., Menéndez P; Servicio de Anatomía Patológica, Hospital Monte Naranco, Oviedo, Spain., Meyer J; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Miao H; Saw Swee Hock School of Public Health, National University of Singapore, Singapore., Miller A; NRG Oncology, Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, New York, USA., Miller N; School of Medicine, National University of Ireland, Galway, Ireland., Mitchell G; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia.; Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Montagna M; Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto (IOV), IRCCS, Padua, Italy., Muir K; Institute of Population Health, University of Manchester, Manchester, UK.; Division of Health Sciences, Warwick Medical School, Warwick University, Coventry, UK., Mulligan AM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada., Mulot C; Université Paris Sorbonne Cité, INSERM UMRS 1147, Paris, France., Nadesan S; City of Hope Clinical Cancer Genomics Community Research Network, Duarte, California, USA., Nathanson KL; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, USA., Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Nevelsteen I; Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Niederacher D; Department of Gynecology and Obstetrics, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Nielsen SF; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Nordestgaard BG; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Norman A; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Nussbaum RL; Department of Medicine, University of California, San Francisco,San Francisco, California, USA., Olah E; Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary., Olopade OI; Center for Clinical Cancer Genetics and Global Health, University of Chicago, Chicago, Illinois, USA., Olson JE; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Olswold C; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Ong KR; West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Edgbaston, Birmingham, UK., Oosterwijk JC; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Orr N; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Osorio A; Human Genetics Group, Human Cancer Genetics Programme, Spanish National Cancer Centre (CNIO), Madrid, Spain.; Spanish Network on Rare Diseases (CIBERER), Madrid, Spain., Pankratz VS; University of New Mexico Health Sciences Center, University of New Mexico, Albuquerque, New Mexico, USA., Papi L; Unit of Medical Genetics, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence, Italy., Park-Simon TW; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Paulsson-Karlsson Y; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Lloyd R; Curtin UWA Centre for Genetic Origins of Health and Disease, Curtin University and University of Western Australia, Perth, Western Australia, Australia., Pedersen IS; Section of Molecular Diagnostics, Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark., Peissel B; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Istituto Nazionale dei Tumori (INT), Milan, Italy., Peixoto A; Department of Genetics, Portuguese Oncology Institute, Porto, Portugal., Perez JIA; Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo, Spain., Peterlongo P; IFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy., Peto J; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK., Pfeiler G; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Phelan CM; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA., Pinchev M; Clalit National Cancer Control Center, Haifa, Israel., Plaseska-Karanfilska D; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', Macedonian Academy of Sciences and Arts, Skopje, Macedonia., Poppe B; Center for Medical Genetics, Ghent University, Ghent, Belgium., Porteous ME; South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, UK., Prentice R; Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Presneau N; Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, UK., Prokofieva D; Department of Genetics and Fundamental Medicine, Bashkir State University, Ufa, Russian Federation., Pugh E; Center for Inherited Disease Research (CIDR), Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Pujana MA; ProCURE, Catalan Institute of Oncology, IDIBELL (Bellvitge Biomedical Research Institute), Barcelona, Spain., Pylkäs K; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland., Rack B; Department of Gynecology and Obstetrics, Ludwig Maximilians University of Munich, Munich, Germany.; Department of Gynaecology and Obstetrics, University of Ulm, Ulm, Germany., Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Istituto Nazionale dei Tumori (INT), Milan, Italy., Rahman N; Section of Cancer Genetics, The Institute of Cancer Research, London, UK., Rantala J; Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden., Rappaport-Fuerhauser C; Department of Obstetrics and Gynaecology and Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria., Rennert G; Clalit National Cancer Control Center, Haifa, Israel.; Carmel Medical Center and B. Rappaport Faculty of Medicine-Technion, Haifa, Israel., Rennert HS; Clalit National Cancer Control Center, Haifa, Israel.; Carmel Medical Center and B. Rappaport Faculty of Medicine-Technion, Haifa, Israel., Rhenius V; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Rhiem K; Center for Familial Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Richardson A; Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Rodriguez GC; Division of Gynecologic Oncology, NorthShore University HealthSystem, University of Chicago, Evanston, Illinois, USA., Romero A; Medical Oncology Department, CIBERONC, Hospital Clínico San Carlos, Madrid, Spain.; Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain., Romm J; Center for Inherited Disease Research (CIDR), Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Rookus MA; Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Rudolph A; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Ruediger T; Institute of Pathology, Staedtisches Klinikum Karlsruhe, Karlsruhe, Germany., Saloustros E; Hereditary Cancer Clinic, University Hospital of Heraklion, Heraklion, Greece., Sanders J; Department of Pathology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Sandler DP; Epidemiology Branch, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA., Sangrajrang S; National Cancer Institute, Bangkok, Thailand., Sawyer EJ; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio, USA., Schmidt DF; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Schoemaker MJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Schumacher F; Research Oncology, Guy's Hospital, King's College London, London, UK., Schürmann P; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Schwentner L; Department of Gynaecology and Obstetrics, University of Ulm, Ulm, Germany., Scott C; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Scott RJ; Division of Molecular Medicine, Pathology North, John Hunter Hospital, Newcastle, New South Wales, Australia.; Discipline of Medical Genetics, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, New South Wales, Australia., Seal S; Section of Cancer Genetics, The Institute of Cancer Research, London, UK., Senter L; Clinical Cancer Genetics Program, Division of Human Genetics, Department of Internal Medicine, Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA., Seynaeve C; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Shah M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Sharma P; Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA., Shen CY; School of Public Health, China Medical University, Taichung, Taiwan.; Taiwan Biobank, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Sheng X; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Shimelis H; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Shrubsole MJ; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Side LE; North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Trust, London, UK., Singer CF; Department of Obstetrics and Gynaecology and Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria., Sohn C; National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany., Southey MC; Department of Pathology, University of Melbourne, Melbourne, Victoria, Australia., Spinelli JJ; Cancer Control Research, BC Cancer Agency, Vancouver, British Columbia, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada., Spurdle AB; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Stegmaier C; Saarland Cancer Registry, Saarbrücken, Germany., Stoppa-Lyonnet D; Service de Génétique Oncologique and INSERM U830, Institut Curie, Paris, France - Université Paris Descartes, Sorbonne Paris Cité., Sukiennicki G; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Surowy H; Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany.; Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany., Sutter C; Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany., Swerdlow A; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, UK., Szabo CI; National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Tamimi RM; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Tan YY; Department of Obstetrics and Gynaecology and Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria., Taylor JA; Epidemiology Branch, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA.; Epigenetic and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA., Tejada MI; Molecular Genetics Laboratory, Clinical Genetics Service, Cruces University Hospital and BioCruces Health Research Institute, Barakaldo, Spain., Tengström M; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Cancer Center, Kuopio University Hospital, Kuopio, Finland.; Institute of Clinical Medicine, Oncology, University of Eastern Finland, Kuopio, Finland., Teo SH; Cancer Research Malaysia, Subang Jaya, Malaysia.; Breast Cancer Research Unit, Cancer Research Institute, University Malaya Medical Centre, Kuala Lumpur, Malaysia., Terry MB; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA., Tessier DC; McGill University and Génome Québec Innovation Centre, Montréal, Québec, Canada., Teulé A; Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, Barcelona, Spain., Thöne K; Department of Cancer Epidemiology, Clinical Cancer Registry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Thull DL; Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Tibiletti MG; Ospedale di Circolo ASST Settelaghi, Varese, Italy., Tihomirova L; Latvian Biomedical Research and Study Centre, Riga, Latvia., Tischkowitz M; Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montréal, Québec, Canada.; Department of Medical Genetics, Addenbrooke's Treatment Centre, Addenbrooke's Hospital, Cambridge, UK., Toland AE; Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA., Tollenaar RAEM; Department of Surgery, Leiden University Medical Center, Leiden, the Netherlands., Tomlinson I; Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK., Tong L; Center for Cancer Epidemiology and Prevention, University of Chicago, Chicago, Illinois, USA., Torres D; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Human Genetics, Pontificia Universidad Javeriana, Bogotá, Colombia., Tranchant M; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada., Truong T; Cancer and Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France., Tucker K; Hereditary Cancer Clinic, Department of Medical Oncology, Prince of Wales Hospital, Randwick, New South Wales, Australia., Tung N; Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Tyrer J; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Ulmer HU; Frauenklinik der Stadtklinik Baden Baden, Baden Baden, Germany., Vachon C; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., van Asperen CJ; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands., Van Den Berg D; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., van den Ouweland AMW; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands., van Rensburg EJ; Cancer Genetics Laboratory, Department of Genetics, University of Pretoria, Arcadia, South Africa., Varesco L; Unit of Hereditary Cancer, Department of Epidemiology, Prevention and Special Functions, IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) AOU San Martino, IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy., Varon-Mateeva R; Institute of Human Genetics, Campus Virchov Klinikum, Charite Berlin, Berlin, Germany., Vega A; Fundación Pública Galega de Medicina Xenómica, Servizo Galego de Saúde SERGAS, Instituto de Investigaciones Sanitarias (IDIS), Santiago de Compostela, Spain.; Grupo de Medicina Xenómica, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Viel A; Unit of Functional Onco-genomics and Genetics, CRO Aviano, National Cancer Institute, Aviano, Italy., Vijai J; Clinical Genetics Research Laboratory, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Vincent D; McGill University and Génome Québec Innovation Centre, Montréal, Québec, Canada., Vollenweider J; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Walker L; Oxford Regional Genetics Service, Churchill Hospital, Oxford, UK., Wang Z; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Wang-Gohrke S; Department of Gynaecology and Obstetrics, University of Ulm, Ulm, Germany., Wappenschmidt B; Center for Familial Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Weinberg CR; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA., Weitzel JN; Clinical Cancer Genetics, City of Hope, Duarte, California, USA., Wendt C; Department of Oncology, Pathology, Karolinska Institutet, Stockholm, Sweden., Wesseling J; Division of Molecular Pathology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.; Department of Pathology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Whittemore AS; Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California, USA.; Department of Biomedical Data Sciences, Stanford University School of Medicine, Stanford, California, USA., Wijnen JT; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands., Willett W; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Winqvist R; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland., Wolk A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Wu AH; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Xia L; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Yang XR; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA., Yannoukakos D; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece., Zaffaroni D; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Istituto Nazionale dei Tumori (INT), Milan, Italy., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Zhu B; Cancer Genomics Research Laboratory (CGR), Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Ziogas A; Department of Epidemiology, University of California, Irvine, Irvine, California, USA., Ziv E; Department of Medicine, Institute for Human Genetics, UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California, USA., Zorn KK; Ospedale di Circolo ASST Settelaghi, Varese, Italy., Gago-Dominguez M; Genomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, Servizo Galego de Saúde SERGAS, Santiago de Compostela, Spain.; Moores Cancer Center, University of California, San Diego, La Jolla, California, USA., Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland., Olsson H; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden., Teixeira MR; Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.; Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal., Stone J; Curtin UWA Centre for Genetic Origins of Health and Disease, Curtin University and University of Western Australia, Perth, Western Australia, Australia.; Department of Obstetrics and Gynaecology, University of Melbourne and the Royal Women's Hospital, Melbourne, Victoria, Australia., Offit K; Clinical Genetics Research Laboratory, Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Ottini L; Department of Molecular Medicine, University La Sapienza, Rome, Italy., Park SK; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea., Thomassen M; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, South General Hospital, Stockholm, Sweden., Meindl A; Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany., Schmutzler RK; Center for Familial Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Droit A; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada., Bader GD; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada., Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Kraft P; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. 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Publikováno v: Nature genetics [Nat Genet] 2017 Dec; Vol. 49 (12), pp. 1767-1778. Date of Electronic Publication: 2017 Oct 23.