Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bobby W.K. Lee"'
Autor:
Manal A. Swairjo, Adriana Bon Ramos, Bobby W.K. Lee, Adeba Mohammad, Dirk Iwata-Reuyl, Maryam Kiani, Spencer William Cohen, Boguslaw Stec
Publikováno v:
Biomolecules
Biomolecules; Volume 7; Issue 1; Pages: 30
Biomolecules, Vol 7, Iss 1, p 30 (2017)
Biomolecules; Volume 7; Issue 1; Pages: 30
Biomolecules, Vol 7, Iss 1, p 30 (2017)
QueF enzymes catalyze the nicotinamide adenine dinucleotide phosphate (NADPH)-dependent reduction of the nitrile group of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in the biosynthetic pathway to the tRNA modified nucleosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e11a88bd8d9b9589740f593c4de2fa
https://pubmed.ncbi.nlm.nih.gov/28300774
https://pubmed.ncbi.nlm.nih.gov/28300774
Autor:
Bobby W.K. Lee, Dirk Iwata-Reuyl, Boguslaw Stec, Vimbai M. Chikwana, Manal A. Swairjo, Valérie de Crécy-Lagard
Publikováno v:
Journal of Biological Chemistry. 287:30560-30570
The enzyme QueF catalyzes the reduction of the nitrile group of 7-cyano-7-deazaguanine (preQ(0)) to 7-aminomethyl-7-deazaguanine (preQ(1)), the only nitrile reduction reaction known in biology. We describe here two crystal structures of Bacillus subt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ce18d8656b96e602c8ea6dd3cffda5
https://doi.org/10.1074/jbc.m112.388538
https://doi.org/10.1074/jbc.m112.388538
Autor:
Zhaohui Sunny Zhou, Tianzhu Zang, Bobby W.K. Lee, Shujia Dai, Kathryn A. Ritter, Thomas K. Wood, Lisa M. Cannon, Dacheng Ren
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:6200-6204
Halogenated furanones, a group of natural products initially isolated from marine red algae, are known to inhibit bacterial biofilm formation, swarming, and quorum sensing. However, their molecular targets and the precise mode of action remain elusiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d887eccfb25fcb06293c74ef78e33ed
https://doi.org/10.1016/j.bmcl.2009.08.095
https://doi.org/10.1016/j.bmcl.2009.08.095
Autor:
Shujia Dai, Barry L. Karger, Bobby W.K. Lee, Suli Liu, Zhaohui Sunny Zhou, Tianzhu Zang, Dajun Chen
Publikováno v:
Analytical Chemistry. 81:9065-9071
Elevated blood levels of homocysteine (Hcy), hyperhomocysteinemia or homocystinuria, have been associated with various diseases and conditions. Homocysteine thiolactone (Hcy TL) is a metabolite of Hcy and reacts with amine groups in proteins to form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760bb33f847bb735d7c5488c10a83f79
https://doi.org/10.1021/ac9017132
https://doi.org/10.1021/ac9017132
Autor:
Inbal Jona, Jinsoo Lim, Ankita Ritwik, Ronald R. Breaker, Wade C. Winkler, Rüdiger Welz, Elizabeth E. Regulski, Bobby W.K. Lee, Adam Roth, Dirk Iwata-Reuyl, Jeffrey E. Barrick, Jane N. Kim
Publikováno v:
Nature Structural & Molecular Biology. 14:308-317
A previous bioinformatics-based search for riboswitches yielded several candidate motifs in eubacteria. One of these motifs commonly resides in the 5' untranslated regions of genes involved in the biosynthesis of queuosine (Q), a hypermodified nucleo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7af67592db338a7995c7e432998de84
https://doi.org/10.1038/nsmb1224
https://doi.org/10.1038/nsmb1224
Autor:
Paul Schimmel, Bobby W.K. Lee, Manal A. Swairjo, Shannon Brown, Steven G. Van Lanen, Valérie de Crécy-Lagard, Dirk Iwata-Reuyl, Robert Reddy
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 61:945-948
QueF (MW = 19.4 kDa) is a recently characterized nitrile oxidoreductase which catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine, a late step in the biosynthesis of the modified tRNA nucleoside q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2348f122a48059e5db6c924a40e0259a
https://doi.org/10.1107/s1744309105029246
https://doi.org/10.1107/s1744309105029246
Publikováno v:
The FASEB Journal. 28
The enzyme QueF catalyzes the NADPH-dependent reduction of the nitrile group of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in the biosynthesis pathway to the tRNA modified nucleoside Queuosine. The only nitrile reductase k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28d187488e61b629cc94a079fde589b6
https://doi.org/10.1096/fasebj.28.1_supplement.lb136
https://doi.org/10.1096/fasebj.28.1_supplement.lb136
Autor:
Bobby W.K. Lee, Patricia A. Richardson, Brett M. Tyler, Chuanxue Hong, Zhaohui Sunny Zhou, Ping Kong
Publikováno v:
BMC Microbiology, Vol 10, Iss 1, p 313 (2010)
BMC Microbiology
BMC Microbiology
Background Oomycetes attack a huge variety of economically and ecologically important plants. These pathogens release, detect and respond to signal molecules to coordinate their communal behaviors including the infection process. When signal molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e603470eea1b242bd7fc5e0e7d0d2ea6
http://www.biomedcentral.com/1471-2180/10/313
http://www.biomedcentral.com/1471-2180/10/313
Publikováno v:
Journal of the American Chemical Society. 132(11)
S-adenosylmethionine (AdoMet or SAM)-dependent methyltransferases belong to a large and diverse family of group-transfer enzymes that perform vital biological functions on a host of substrates. Despite the progress in genomics, structural proteomics,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcda1b64210742aa2c2a8459c1c414f7
https://pubmed.ncbi.nlm.nih.gov/20196537
https://pubmed.ncbi.nlm.nih.gov/20196537
Zoosporic plant pathogens produce bacterial autoinducer-2 that affects Vibrio harveyi quorum sensing
Publikováno v:
FEMS microbiology letters. 303(1)
The frequent coisolation of bacteria with Phytophthora and Pythium species suggests possible interspecies communication. Zoospore-free fluids (ZFF) from bacteria-free and nutrient-depleted zoospore suspensions were examined to investigate the product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31fd554f75c2027cb83523cf07082a2
https://pubmed.ncbi.nlm.nih.gov/20002192
https://pubmed.ncbi.nlm.nih.gov/20002192