Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bobby Kwan"'
Autor:
Shivendra G. Tewari, Rubayet Elahi, Bobby Kwan, Krithika Rajaram, Suyash Bhatnagar, Jaques Reifman, Sean T. Prigge, Akhil B. Vaidya, Anders Wallqvist
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-17 (2023)
Abstract Background Spiroindolone and pyrazoleamide antimalarial compounds target Plasmodium falciparum P-type ATPase (PfATP4) and induce disruption of intracellular Na+ homeostasis. Recently, a PfATP4 mutation was discovered that confers resistance
Externí odkaz:
https://doaj.org/article/18aa92bdf81649a3b8d6c816f612d5e3
Autor:
Shivendra G. Tewari, Bobby Kwan, Rubayet Elahi, Krithika Rajaram, Jaques Reifman, Sean T. Prigge, Akhil B. Vaidya, Anders Wallqvist
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Due to the recurring loss of antimalarial drugs to resistance, there is a need for novel targets, drugs, and combination therapies to ensure the availability of current and future countermeasures. Pyrazoleamides belong to a novel class of an
Externí odkaz:
https://doaj.org/article/337b151f45e04a698ac56a2a2ef20345
Autor:
Shivendra G. Tewari, Krithika Rajaram, Russell P. Swift, Bobby Kwan, Jaques Reifman, Sean T. Prigge, Anders Wallqvist
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-14 (2021)
Abstract Background Cultured human red blood cells (RBCs) provide a powerful ex vivo assay platform to study blood-stage malaria infection and propagation. In recent years, high-resolution metabolomic methods have quantified hundreds of metabolites f
Externí odkaz:
https://doaj.org/article/6c007481d1644ae8802cc1a4f751d939
Autor:
Russell P Swift, Krithika Rajaram, Cyrianne Keutcha, Hans B Liu, Bobby Kwan, Amanda Dziedzic, Anne E Jedlicka, Sean T Prigge
Publikováno v:
eLife, Vol 9 (2020)
The apicoplast of Plasmodium falciparum parasites is believed to rely on the import of three-carbon phosphate compounds for use in organelle anabolic pathways, in addition to the generation of energy and reducing power within the organelle. We genera
Externí odkaz:
https://doaj.org/article/8ba230931280402babefe27f33d8cdda
Autor:
Russell P. Swift, Krithika Rajaram, Bobby Kwan, Sean T. Prigge, Jaques Reifman, Anders Wallqvist, Shivendra G. Tewari
Publikováno v:
Malaria Journal
Malaria Journal, Vol 20, Iss 1, Pp 1-14 (2021)
Malaria Journal, Vol 20, Iss 1, Pp 1-14 (2021)
Background Cultured human red blood cells (RBCs) provide a powerful ex vivo assay platform to study blood-stage malaria infection and propagation. In recent years, high-resolution metabolomic methods have quantified hundreds of metabolites from paras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5922cb29cc8ef1ee7d6d7119d466a09c
https://resolver.caltech.edu/CaltechAUTHORS:20210729-174340563
https://resolver.caltech.edu/CaltechAUTHORS:20210729-174340563
Autor:
Cyrianne Keutcha, Amanda Dziedzic, Sean T. Prigge, Hans B. Liu, Bobby Kwan, Krithika Rajaram, Russell P. Swift, Anne E. Jedlicka
Publikováno v:
eLife, Vol 9 (2020)
The apicoplast of Plasmodium falciparum parasites is believed to rely on the import of three-carbon phosphate compounds for use in organelle anabolic pathways, in addition to the generation of energy and reducing power within the organelle. We genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd371cee68d9b2186e4c599d05f31c8
https://doi.org/10.7554/elife.50807
https://doi.org/10.7554/elife.50807
Autor:
Russell P, Swift, Krithika, Rajaram, Cyrianne, Keutcha, Hans B, Liu, Bobby, Kwan, Amanda, Dziedzic, Anne E, Jedlicka, Sean T, Prigge
Publikováno v:
eLife
The apicoplast of Plasmodium falciparum parasites is believed to rely on the import of three-carbon phosphate compounds for use in organelle anabolic pathways, in addition to the generation of energy and reducing power within the organelle. We genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7350938b7ed37a3c9eeac6e6362eb2b5
https://pubmed.ncbi.nlm.nih.gov/32815516
https://pubmed.ncbi.nlm.nih.gov/32815516
Autor:
Helena Tydén, Anders A Bengtsson, Christian Lood, Bobby Kwanghoon Han, Katherine D Wysham, Kevin C Cain
Publikováno v:
Lupus Science and Medicine, Vol 7, Iss 1 (2020)
Objective Neutrophils contribute to the SLE pathogenesis. Neutrophil to lymphocyte ratio (NLR) is reported to correlate with disease activity in SLE. The aim of the study was to evaluate whether NLR reflects underlying immunopathogenic activity in SL
Externí odkaz:
https://doaj.org/article/3b284d2b50934de8ae912d7c4cb39021
Publikováno v:
Diagnostics, Vol 11, Iss 1, p 20 (2020)
Despite the importance of the early detection of glaucoma, most patients with progressive glaucoma show minimal symptoms. We aimed to evaluate biomarkers for glaucoma diagnosis in Korea. Forty-two volunteers with/without open-angle glaucoma were enro
Externí odkaz:
https://doaj.org/article/26363ee4c3404228a84a7d0ec1c3f814