Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bobby Joe Payne"'
Publikováno v:
Veterinary Pathology. 46:313-324
UDP-GlcNAc: lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (GlcNAc-1-phosphotransferase) is an α2β2γ2 hexameric enzyme that catalyzes the first step in the synthesis of the mannose 6-phosphate targeting signal on lysosomal hydrolases. I
Publikováno v:
Journal of Biological Chemistry. 282:27198-27203
UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (GlcNAc-1-phosphotransferase) mediates the first step in the synthesis of the mannose 6-phosphate recognition marker on acid hydrolases. The transferase exists as an alpha(2)beta(2)
Autor:
C. Jones, T. Issa, C. M. Gelfman, David R. Powell, Peter Vogel, Gwenn M. Hansen, Bobby Joe Payne, Meagan R. Pitcher, Christopher M. DaCosta, R. B. Vance, Zhi-Ming Ding, Melanie K. Shadoan, R. Read
Publikováno v:
Veterinary pathology. 52(3)
Mice deficient in TMEM218 ( Tmem218–/–) were generated as part of an effort to identify and validate pharmaceutically tractable targets for drug development through large-scale phenotypic screening of knockout mice. Routine diagnostics, expressio
Autor:
Bobby Joe Payne, Anusyah Rathkrishnan, Yin Quan Tang, Kien Chai Ong, Rishya Manikam, Shamala Devi Sekaran, Seok Mui Wang, Indu Bala Jaganath, Sau Har Lee
Publikováno v:
BMC Complementary and Alternative Medicine
Background The absence of commercialized vaccines and antiviral agents against dengue has made the disease a major health concern around the world. With the current dengue virus transmission rate and incidences, the development of antiviral drugs is
Autor:
Bobby Joe Payne, Arthur T. Sands, Daniel L. Small, Peter Vogel, Gwenn M. Hansen, Brian Zambrowicz, R. Read
Publikováno v:
Veterinary pathology. 49(1)
There is evidence that genetic factors play a role in the complex multifactorial pathogenesis of hydrocephalus. Identification of the genes involved in the development of this neurologic disorder in animal models may elucidate factors responsible for
Autor:
Xuemei Liu, Jeffrey A. Kramer, William Heydorn, Bobby Joe Payne, Xiang-Qing Yu, Megan E. Phillips, Emily O’Neill, Amr Nouraldeen, Debra Bruce, Sairam Bellum, Peter Vogel, Suma Gopinathan, Alan Wilson, Melinda M. Albright, R. Read, Traci Smith
Publikováno v:
Toxicologic pathology. 38(3)
The rat has been the preferred rodent toxicology species since before regulatory requirements have been in place, and there exists in the pharmaceutical industry and the regulatory agencies a significant amount of historical data for the rat. The res
Publikováno v:
Archives of toxicology. 67(1)
The effects of equimolar doses of the triphenylethylene antiestrogens tamoxifen and toremifene on female Sprague-Dawley rat liver were studied in a 52-week toxicity study which included a 13-week recovery period. Liver tumors were found in four out o
Autor:
Tibor Balazs, Bobby Joe Payne
Publikováno v:
Toxicology and Applied Pharmacology. 20:442-445
Two antihypertensive agents, SK&F 24260 and hydralazine, given to dogs for 2 and 5 consecutive days, respectively, caused focal necrosis in the papillary muscles of the left ventricles. Longer administration of SK&F 24260 in lower doses produced an a
Publikováno v:
Toxicology Letters. 18:21
Autor:
Bobby Joe Payne, F. G. J. Hayhoe
Publikováno v:
Pathologia veterinaria. 7:87-87