Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Bobby J Cherayil"'
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0279372 (2022)
Salmonella enterica serovars Typhimurium and Typhi are enteropathogens that differ in host range and the diseases that they cause. We found that exposure to a combination of hypotonicity and the detergent Triton X-100 significantly reduced the viabil
Externí odkaz:
https://doaj.org/article/fe4925f7f25e4d1cac9f8819ccaab5fe
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160937 (2016)
Gut commensal bacteria contribute to the pathogenesis of inflammatory bowel disease, in part by activating the inflammasome and inducing secretion of interleukin-1ß (IL-1ß). Although much has been learned about inflammasome activation by bacterial
Externí odkaz:
https://doaj.org/article/d8bc426ce8d841cdaf4ddc361b345123
Autor:
Nanda Kumar N Shanmugam, Shiri Ellenbogen, Estela Trebicka, Lijian Wang, Subhankar Mukhopadhyay, Adam Lacy-Hulbert, Carey Ann Gallini, Wendy S Garrett, Bobby J Cherayil
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38136 (2012)
Abnormal expression of the liver peptide hormone hepcidin, a key regulator of iron homeostasis, contributes to the pathogenesis of anemia in conditions such as inflammatory bowel disease (IBD). Since little is known about the mechanisms that control
Externí odkaz:
https://doaj.org/article/9defec2c10fa44c791073893257377ba
Autor:
Jordan Philpott, Simon Kazimierczyk, Parimal Korgaonkar, Evan Bordt, Jaclyn Zois, Chithirachelvi Vasudevan, Di Meng, Ishan Bhatia, Naifang Lu, Brittany Jimena, Caryn Porter, Bobby J. Cherayil, Nitya Jain
Publikováno v:
ImmunoHorizons. 6:366-372
Resident tissue macrophages (RTMs) develop from distinct waves of embryonic progenitor cells that seed tissues before birth. Tissue-specific signals drive a differentiation program that leads to the functional specialization of RTM subsets. Genetic p
Autor:
Bobby J. Cherayil, Chithirachelvi Vasudevan, Vladimir Yeliseyev, Nitya Jain, Stefan Halvorsen, Samira Ibrahim, Shaniah Prosper, Slim Sassi, Smriti Verma, Maria Ennamorati, Kara Clerkin, Joseph A. Gardecki, Brian Seed, Lynn Bry, Caryn Porter, Margot Kim, Guillermo J. Tearney
Publikováno v:
Proc Natl Acad Sci U S A
The thymus generates cells of the T cell lineage that seed the lymphatic and blood systems. Transcription factor regulatory networks control the lineage programming and maturation of thymic precursor cells. Whether extrathymic antigenic events, such
Autor:
Chien-wen Su, Catherine Stanton, Bobby J. Cherayil, Shane O’Donnell, Chih-Yu Chen, Tangyou Mao, Shao Rong Long, Lefei Jiao, Hai Ning Shi, Qiaorong Ji, W. Allan Walker, Shasha Zheng
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 4, Pp 763-778 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Epidemiological and animal studies have indicated an inverse correlation between the rising prevalence of obesity and metabolic syndrome and exposure to helminths. Whether helminth-induced immune response contributes to microbiota r
Autor:
Bobby J. Cherayil, Smriti Verma, Rachel A Prescott, Alessio Fasano, Christina S. Faherty, Laura A. MacKenzie Ingano, Emily Hill, Kourtney P. Nickerson, Stefania Senger
Publikováno v:
Gut Microbes
Gut Microbes, Vol 11, Iss 3, Pp 526-538 (2020)
Gut Microbes, Vol 11, Iss 3, Pp 526-538 (2020)
Salmonella enterica serovar Typhi is the etiologic agent of typhoid fever, a major public health problem in the developing world. Moving toward and adhering to the intestinal epithelium represents key initial steps of infection by S. Typhi. We examin
Publikováno v:
Microorganisms
Microorganisms, Vol 8, Iss 504, p 504 (2020)
Microorganisms, Vol 8, Iss 504, p 504 (2020)
The molecular complexity of host-pathogen interactions remains poorly understood in many infectious diseases, particularly in humans due to the limited availability of reliable and specific experimental models. To bridge the gap between classical two
Autor:
George M. Varghese, Bobby J. Cherayil, Kavitha M Lakshmi, Jeshina Janardhanan, Vijayakumar T. S, Sadhana Yadav, Vijay Prakash Turaka
Publikováno v:
International Journal of Infectious Diseases, Vol 85, Iss, Pp 132-134 (2019)
Objectives: Mycobacterium tuberculosis produces high-affinity siderophores that play essential roles in iron acquisition and tuberculosis (TB) pathogenesis. In response, host cells secrete a siderophore-binding protein, siderocalin, to limit the bact
Autor:
Bobby J. Cherayil, Hai Ning Shi, Chien-wen Su, Shao Rong Long, Yali Li, Libo Su, W Zhang, Jeffrey Chang, W A Walker, Ramnik J. Xavier
Publikováno v:
Mucosal immunology
Infection with the intestinal helminth parasite Heligmosomoides polygyrus exacerbates the colitis caused by the bacterial enteropathogen Citrobacter rodentium. To clarify the underlying mechanism, we analyzed fecal microbiota composition of control a