Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bobby Brillantes"'
Autor:
Weiru Wang, Kristi Elkins, Angela Oh, Yen-Ching Ho, Jiansheng Wu, Hong Li, Yang Xiao, Mandy Kwong, Mary Coons, Bobby Brillantes, Eric Cheng, Lisa Crocker, Peter S Dragovich, Deepak Sampath, Xiaozhang Zheng, Kenneth W Bair, Thomas O'Brien, Lisa D Belmont
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109366 (2014)
Inhibiting NAD biosynthesis by blocking the function of nicotinamide phosphoribosyl transferase (NAMPT) is an attractive therapeutic strategy for targeting tumor metabolism. However, the development of drug resistance commonly limits the efficacy of
Externí odkaz:
https://doaj.org/article/bb7aac885fbb499794f3ed2668eeafc5
Autor:
Jun Chen, Justin Elstrott, Lan Wang, Simon S. Gao, Richard A.D. Carano, Jose E. Heredia, Elisia Villemure, Daniel G. Shore, Wyne P. Lee, Bobby Brillantes, Joseph H. Lin, Liling Liu, David H. Hackos, Jens Kortmann, Matthew Volgraf, Daniel D. Bravo, Christine Tam, Lorena Riol-Blanco, Steven Magnuson, Lionel Rouge, Chris Bjornson, Baihua Hu, Tania Chernov-Rogan, Rebecca M. Reese, Christopher P. Arthur, Min Jung, Michelle Dourado, Xiumin Wu, Victory Joseph, Alberto Estevez, John Liu, Alvin Gogineni, Juan Zhang, Laurie Leong, Jian Payandeh, Vishal Verma, Shannon D. Shields, Han Ting Ding, Brian Safina, Alessia Balestrini, Yong Chen, Vineela D. Gandham, Eric Suto, Jianyong Wang, Justin Ly, Rebecca N. Bauer, Jonas Doerr, Alexis Rohou, Cary D. Austin, Jason A. Vander Heiden, Xiaoying Yang, Ryan L. Wong, Lucinda Tam, Liuxi Chen, Kathy Hötzel, Kai H. Barck, Merone Roose-Girma, Claudio Ciferri, Huifen Chen, Bianca M. Liederer
Publikováno v:
Journal of Experimental Medicine. 218
Despite the development of effective therapies, a substantial proportion of asthmatics continue to have uncontrolled symptoms, airflow limitation, and exacerbations. Transient receptor potential cation channel member A1 (TRPA1) agonists are elevated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7586a7b163f0274f73ff2d6634f422f1
https://doi.org/10.1084/jem.20201637
https://doi.org/10.1084/jem.20201637
Autor:
Bobby Brillantes, David H. Hackos, Chang Liu, Demi Maria Zabala Greiner, Lionel Rouge, Jie Zheng, Jian Payandeh, Tianbo Li, Shannon D. Shields, Jun Chen, Matthew Volgraf, Satoko Kakiuchi-Kiyota, Steve Magnuson, Simon Vu, Brian Safina, Rebecca M. Reese, Yu Patrick Shi, Huifen Chen, Tania Chernov-Rogan, Pawan Bir Kohli, Alexis Rohou, Jianyong Wang, Christine Tam, Kevin M. Johnson
Publikováno v:
Neuron, vol 109, iss 2
The TRPA1 ion channel is activated by electrophilic compounds through the covalent modification of intracellular cysteine residues. How non-covalent agonists activate the channel and whether covalent and non-covalent agonists elicit the same physiolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6daefc23efa2033713d1bd3205032a40
https://pubmed.ncbi.nlm.nih.gov/33476560
https://pubmed.ncbi.nlm.nih.gov/33476560
Autor:
Edward, Kraft, Yvonne, Franke, Katharine, Heeringa, Stephanie, Shriver, Inna, Zilberleyb, Christine, Kugel, Trisha, Dela Vega, Athena, Wong, Bobby, Brillantes, Claudio, Ciferri, George, Dutina, Grace, Lee, Isabelle, Lehoux, Zhong Rong, Li, Lee, Lior-Hoffmann, Jiyoung, Hwang, Chris, Lonergan, Lynn, Martin, Kyle, Mortara, Lananh, Nguyen, Jian, Payandeh, Andrew, Perez, Jun, Sampang, Lovejit, Singh, Kurt, Schroeder, Christine, Tam, Shu, Ti, Ye Naing, Win, Krista, Bowman
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2025
The expression analysis of recombinant proteins is a challenging step in any high-throughput protein production pipeline. Often multiple expression systems and a variety of expression construct designs are considered for the production of a protein o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ab1eb146afa09a087594f656116686d
https://pubmed.ncbi.nlm.nih.gov/31267448
https://pubmed.ncbi.nlm.nih.gov/31267448
Autor:
Lananh Nguyen, George Dutina, Chris Lonergan, Yvonne Franke, Shu Ti, Katharine Heeringa, Lovejit Singh, Christine Tam, Kyle Mortara, Kurt Schroeder, Andrew Perez, Claudio Ciferri, Bobby Brillantes, Athena W. Wong, Jiyoung Hwang, Edward Kraft, Isabelle Lehoux, Trisha Dela Vega, Krista K. Bowman, Christine Kugel, Jian Payandeh, Lee Lior-Hoffmann, L. Martin, Zhong Rong Li, Stephanie Shriver, Ye Naing Win, Inna Zilberleyb, Jun Sampang, Grace Lee
Publikováno v:
Methods in Molecular Biology ISBN: 9781493996230
The expression analysis of recombinant proteins is a challenging step in any high-throughput protein production pipeline. Often multiple expression systems and a variety of expression construct designs are considered for the production of a protein o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6daa6c3871329e62d4e07adbfca39b9f
https://doi.org/10.1007/978-1-4939-9624-7_3
https://doi.org/10.1007/978-1-4939-9624-7_3
Autor:
Brian Safina, Honorio Sampang, Bobby Brillantes, Christopher M. Koth, Hoangdung Ho, Shivani Ahuja, Sophia Lin, Christoph Martin Dehnhardt, Krista K. Bowman, Michael Edward Grimwood, Ping Wu, Melissa A. Starovasnik, David H. Hackos, Christine Tam, J. P. Johnson, Charles J. Cohen, Zhiwei Xie, Jian Payandeh, Yvonne Franke, Kuldip Khakh, Mary Coons, Kevin R Clark, Jun Li, Susmith Mukund, Elaine Chang, Jean-Christophe Andrez, Stephanie Shriver, Daniel F. Ortwine, Kyle Mortara, Clint Young, Alberto Estevez, Henry Verschoof, Thilo Focken, Daniel P. Sutherlin, Lunbin Deng
Publikováno v:
Science. 350
Voltage-gated sodium (Nav) channels propagate action potentials in excitable cells. Accordingly, Nav channels are therapeutic targets for many cardiovascular and neurological disorders. Selective inhibitors have been challenging to design because the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ca24c2468f257b0ad883c68b2e4c30
https://doi.org/10.1126/science.aac5464
https://doi.org/10.1126/science.aac5464
Autor:
Angela Oh, Mandy Kwong, Bobby Brillantes, Eric Cheng, Thomas O'Brien, Lisa D. Belmont, Hong Li, Kristi Elkins, Deepak Sampath, Mary Coons, Peter S. Dragovich, Xiaozhang Zheng, Yang Xiao, Jiansheng Wu, Yen-Ching Ho, Weiru Wang, Kenneth W. Bair, Lisa Crocker
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109366 (2014)
PLoS ONE
PLoS ONE
Inhibiting NAD biosynthesis by blocking the function of nicotinamide phosphoribosyl transferase (NAMPT) is an attractive therapeutic strategy for targeting tumor metabolism. However, the development of drug resistance commonly limits the efficacy of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d47e6ba4debfe081f3327e11455806f
http://europepmc.org/articles/PMC4186856?pdf=render
http://europepmc.org/articles/PMC4186856?pdf=render