Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Bobby, Kwan"'
Autor:
Shivendra G. Tewari, Rubayet Elahi, Bobby Kwan, Krithika Rajaram, Suyash Bhatnagar, Jaques Reifman, Sean T. Prigge, Akhil B. Vaidya, Anders Wallqvist
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-17 (2023)
Abstract Background Spiroindolone and pyrazoleamide antimalarial compounds target Plasmodium falciparum P-type ATPase (PfATP4) and induce disruption of intracellular Na+ homeostasis. Recently, a PfATP4 mutation was discovered that confers resistance
Externí odkaz:
https://doaj.org/article/18aa92bdf81649a3b8d6c816f612d5e3
Autor:
Shivendra G. Tewari, Bobby Kwan, Rubayet Elahi, Krithika Rajaram, Jaques Reifman, Sean T. Prigge, Akhil B. Vaidya, Anders Wallqvist
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Due to the recurring loss of antimalarial drugs to resistance, there is a need for novel targets, drugs, and combination therapies to ensure the availability of current and future countermeasures. Pyrazoleamides belong to a novel class of an
Externí odkaz:
https://doaj.org/article/337b151f45e04a698ac56a2a2ef20345
Autor:
Shivendra G. Tewari, Krithika Rajaram, Russell P. Swift, Bobby Kwan, Jaques Reifman, Sean T. Prigge, Anders Wallqvist
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-14 (2021)
Abstract Background Cultured human red blood cells (RBCs) provide a powerful ex vivo assay platform to study blood-stage malaria infection and propagation. In recent years, high-resolution metabolomic methods have quantified hundreds of metabolites f
Externí odkaz:
https://doaj.org/article/6c007481d1644ae8802cc1a4f751d939
Autor:
Russell P Swift, Krithika Rajaram, Cyrianne Keutcha, Hans B Liu, Bobby Kwan, Amanda Dziedzic, Anne E Jedlicka, Sean T Prigge
Publikováno v:
eLife, Vol 9 (2020)
The apicoplast of Plasmodium falciparum parasites is believed to rely on the import of three-carbon phosphate compounds for use in organelle anabolic pathways, in addition to the generation of energy and reducing power within the organelle. We genera
Externí odkaz:
https://doaj.org/article/8ba230931280402babefe27f33d8cdda
Autor:
Russell P. Swift, Krithika Rajaram, Bobby Kwan, Sean T. Prigge, Jaques Reifman, Anders Wallqvist, Shivendra G. Tewari
Publikováno v:
Malaria Journal
Malaria Journal, Vol 20, Iss 1, Pp 1-14 (2021)
Malaria Journal, Vol 20, Iss 1, Pp 1-14 (2021)
Background Cultured human red blood cells (RBCs) provide a powerful ex vivo assay platform to study blood-stage malaria infection and propagation. In recent years, high-resolution metabolomic methods have quantified hundreds of metabolites from paras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5922cb29cc8ef1ee7d6d7119d466a09c
https://resolver.caltech.edu/CaltechAUTHORS:20210729-174340563
https://resolver.caltech.edu/CaltechAUTHORS:20210729-174340563
Autor:
Cyrianne Keutcha, Amanda Dziedzic, Sean T. Prigge, Hans B. Liu, Bobby Kwan, Krithika Rajaram, Russell P. Swift, Anne E. Jedlicka
Publikováno v:
eLife, Vol 9 (2020)
The apicoplast of Plasmodium falciparum parasites is believed to rely on the import of three-carbon phosphate compounds for use in organelle anabolic pathways, in addition to the generation of energy and reducing power within the organelle. We genera
Autor:
Russell P, Swift, Krithika, Rajaram, Cyrianne, Keutcha, Hans B, Liu, Bobby, Kwan, Amanda, Dziedzic, Anne E, Jedlicka, Sean T, Prigge
Publikováno v:
eLife
The apicoplast of Plasmodium falciparum parasites is believed to rely on the import of three-carbon phosphate compounds for use in organelle anabolic pathways, in addition to the generation of energy and reducing power within the organelle. We genera