Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bob Th.R. Wentges"'
Autor:
Bob Th.R. Wentges, A. B. M. Klaassen, Cees A.M. van Ginneken, Yvonne J.B. Van Megen, Jaap F. Rodrigues de Miranda
Publikováno v:
Journal of Allergy and Clinical Immunology. 87:530-540
Nasal hyperreactivity in nasal allergy may be due to changes of the characteristics in adrenergic receptors. Radioligand receptor-binding studies with the antagonists, 3H-prazosin (alpha 1-adrenoceptor), 3H-rauwolscine (alpha 2-adrenoceptor), and 125
Autor:
J. F. Rodrigues De Miranda, C. A. M. Van Ginneken, Bob Th.R. Wentges, A. B. M. Klaassen, Y.J.B. van Megen
Publikováno v:
Journal of Allergy and Clinical Immunology. 87:521-529
Cholinergic nasal hyperresponsiveness in nasal allergy may be due to changes of the characteristics in muscarinic cholinergic receptors. Radioligand receptor binding and in vitro autoradiographic studies of nasal mucosa in nonallergic (NA) and allerg
Autor:
Cees A.M. van Ginneken, Yvonne J.B. Van Megen, Jaap F. Rodrigues de Miranda, Bob Th.R. Wentges, André B. M. Klaassen
Publikováno v:
European Journal of Pharmacology. 182:561-567
The specific binding of [3H]rauwolscine to rat nasal mucosa membranes was saturable, stereoselective and of high affinity. The Scatchard plot pointed to a homogeneous population of binding sites (Kd = 3.6 +/- 0.6 nM; Bmax = 5.1 +/- 0.7 pmol/g). The n
Autor:
Jaap F. Rodrigues de Miranda, Cees A.M. van Ginneken, Yvonne J.B. Van Megen, Bob Th.R. Wentges, Corke J.B.M. Van Ratingen, A. B. M. Klaassen
Publikováno v:
European Journal of Pharmacology. 182:515-525
The specific binding of 125I-(-)-cyanopindolol (125I-(-)-CYP) to homogenates and cryostat sections of rat nasal mucosa was saturable, stereoselective and of high affinity (Kd = 5.0 +/- 0.4 pM. Bmax = 204 +/- 12 fmol/mg protein and Kd = 7.2 +/- 0.7 pM