Zobrazeno 1 - 10
of 289
pro vyhledávání: '"Bob Olsson"'
Autor:
Nicholas C. Cullen, Henrik Zetterberg, Philip S. Insel, Bob Olsson, Ulf Andreasson, the Alzheimer’s Disease Neuroimaging Initiative, Kaj Blennow, Oskar Hansson, Niklas Mattsson‐Carlgren
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 9, Pp 1661-1673 (2020)
Abstract Objective To investigate the statistical power of plasma, imaging, and cognition biomarkers as Alzheimer’s disease (AD) clinical trial outcome measures. Methods Plasma neurofilament light, structural magnetic resonance imaging, and cogniti
Externí odkaz:
https://doaj.org/article/6aac7c2958e143a484d74e78928e9158
Autor:
Ronald Lautner, Philip S. Insel, Tobias Skillbäck, Bob Olsson, Mikael Landén, Giovanni B. Frisoni, Sanna-Kaisa Herukka, Harald Hampel, Anders Wallin, Lennart Minthon, Oskar Hansson, Kaj Blennow, Niklas Mattsson, Henrik Zetterberg
Publikováno v:
Alzheimer’s Research & Therapy, Vol 9, Iss 1, Pp 1-7 (2017)
Abstract Background From earlier studies it is known that the APOE ε2/ε3/ε4 polymorphism modulates the concentrations of cerebrospinal fluid (CSF) beta-amyloid1–42 (Aβ42) in patients with cognitive decline due to Alzheimer’s disease (AD), as
Externí odkaz:
https://doaj.org/article/67b4911748414c20b9b1a7a2bd0dd04e
Autor:
Clara Hjalmarsson, Maria Bjerke, Björn Andersson, Kaj Blennow, Henrik Zetterberg, N. David Åberg, Bob Olsson, Carl Eckerström, Lena Bokemark, Anders Wallin
Publikováno v:
Journal of Central Nervous System Disease, Vol 2014, Iss 6, Pp 51-58 (2014)
Externí odkaz:
https://doaj.org/article/d84f72f8bcea4659a0108f4120d37c15
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72204 (2013)
Obesity is associated with a low-grade inflammation including moderately increased serum levels of the acute phase protein serum amyloid A (SAA). In obesity, SAA is mainly produced from adipose tissue and serum levels of SAA are associated with insul
Externí odkaz:
https://doaj.org/article/502beed852c643249f5c725d63cbee8a
Autor:
Johan Mellergård, Anders Tisell, Olof Dahlqvist Leinhard, Ida Blystad, Anne-Marie Landtblom, Kaj Blennow, Bob Olsson, Charlotte Dahle, Jan Ernerudh, Peter Lundberg, Magnus Vrethem
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44739 (2012)
BACKGROUND: Multiple sclerosis (MS) is associated not only with focal inflammatory lesions but also diffuse pathology in the central nervous system (CNS). Since there is no firm association between the amount of focal inflammatory lesions and disease
Externí odkaz:
https://doaj.org/article/3acc4a5d946f4448855ce449ba8c344e
Autor:
Ronald Lautner, Niklas Mattsson, Michael Schöll, Kristin Augutis, Kaj Blennow, Bob Olsson, Henrik Zetterberg
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2011 (2011)
Intensive research over the last decades has provided increasing evidence for neuroinflammation as an integral part in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease (AD). Inflammatory responses in the central nervous syst
Externí odkaz:
https://doaj.org/article/524d767e3a7046799bd523e727f53920
Autor:
Maja Olsson, Sofie Ahlin, Bob Olsson, Per-Arne Svensson, Marcus Ståhlman, Jan Borén, Lena M S Carlsson, Kajsa Sjöholm
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19609 (2011)
Obesity and obesity co-morbidities are associated with a low grade inflammation and elevated serum levels of acute phase proteins, including serum amyloid A (SAA). In the non-acute phase in humans, adipocytes are major producers of SAA but the functi
Externí odkaz:
https://doaj.org/article/4f33d19e0839411a998cea07742f04e3
Autor:
Maria Eldh, Karin Ekström, Hadi Valadi, Margareta Sjöstrand, Bob Olsson, Margareta Jernås, Jan Lötvall
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15353 (2010)
BackgroundExosomes are small extracellular nanovesicles of endocytic origin that mediate different signals between cells, by surface interactions and by shuttling functional RNA from one cell to another. Exosomes are released by many cells including
Externí odkaz:
https://doaj.org/article/7026957562f54fe8a09d3a8778d8a62c
Publikováno v:
Haematologica, Vol 93, Iss 7 (2008)
Externí odkaz:
https://doaj.org/article/798f60efc12f41669184992670e41cef
Autor:
Kevin Rostasy, Eva Michael, Mar Tulinius, Kaj Blennow, Bob Olsson, Lars Alberg, Anna-Karin Kroksmark, Nicholas C. Cullen, Lisa Wahlgren, Henrik Zetterberg
Publikováno v:
Journal of Neurology
Background Recently, the anti-sense oligonucleotide drug nusinersen was approved for spinal muscular atrophy (SMA) and our aim was to find a response marker for this treatment. Methods Twelve children with SMA type 1 and two copies of the SMN2 gene w