Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Bob Jiang"'
Autor:
Wanchi Fung, Kobayashi Tetsuya, Anita Niedziela-Majka, Bob Jiang, Kim Jordan, Saritha Kusam, David G. Breckenridge, Hai Yang, Britton Kenneth Corkey, Kristyna Elbel, Chin Tay, Elaine Kan, Sammy Metobo, David Sperandio, Du Jinfa, Richard M. Neve, Sophia L. Shevick, Eric B. Lansdon, Kerim Babaoglu, Gregory Chin, Heather Webb, Debi Jin, Annapurna Sapre, Vangelis Aktoudianakis, Latesh Lad, Jamie Bates, Xiaowu Chen, Jeff Zablocki, Gene Eisenberg, Nate Larson, Richard L. Mackman, Martinez Ruben, Magdeleine Hung, Zachary Newby, Mish Michael R
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:457-469
The bromodomain and extra-terminal (BET) family of proteins, consisting of the bromodomains containing protein 2 (BRD2), BRD3, BRD4, and the testis-specific BRDT, are key epigenetic regulators of gene transcription and has emerged as an attractive ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32393d33e86182931fa91168f5389d3c
https://doi.org/10.1016/j.bmc.2018.11.020
https://doi.org/10.1016/j.bmc.2018.11.020
Autor:
Kwan Leung, Ken Rehder, Xiaofen Li, Bob Jiang, Marie Nguyen, Timothy A. Marquart, Nancy Chu, Victoria Y. Maydanik, David Lustig, Kevin D. Shenk, Yuan Li, Elfatih Elzein, Reina Natero, Daniel Soohoo, Prabha Ibrahim, Jeff Zablocki, Suresh S. Kerwar, Dmitry Koltun, Jia Hao, Dewan Zeng
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:6017-6021
New inhibitors of palmitoyl-CoA oxidation are based on the introduction of nitrogen heterocycles in the ‘Western Portion’ of the molecule. SAR studies led to the discovery of CVT-4325 (shown), a potent FOXi (IC50 = 380 nM rat mitochondria) with f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80324da80b70144f2e62fa211bc8e33
https://doi.org/10.1016/j.bmcl.2004.09.077
https://doi.org/10.1016/j.bmcl.2004.09.077
Autor:
Irving Fong, Elfatih Elzein, Prabha Ibrahim, Lin Wu, Jeff Zablocki, Timothy A. Marquart, Yuzhi Wu, David Lustig, Dewan Zeng, Christopher Morrison, Tenning Maa, Bob Jiang, Kevin D. Shenk, Kwan Leung, Venkata Palle, Vaibhav Varkhedkar
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:3793-3797
Atrial fibrillation (AF) is the most commonly encountered sustained clinical arrhythmia with an estimated 2.3 million cases in the US (2001). A(1) adenosine receptor agonists can slow the electrical impulse propagation through the atrioventricular (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd5013dbbffd866cc6467c1064d1f04
https://doi.org/10.1016/j.bmcl.2004.04.096
https://doi.org/10.1016/j.bmcl.2004.04.096