Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Boaz Sat"'
Publikováno v:
PLoS Biology, Vol 6, Iss 12, p e319 (2008)
It was recently reported that the production of Reactive Oxygen Species (ROS) is a common mechanism of cell death induced by bactericidal antibiotics. Here we show that triggering the Escherichia coli chromosomal toxin-antitoxin system mazEF is an ad
Externí odkaz:
https://doaj.org/article/32235f56692046e48fef0f8af5da62f5
Publikováno v:
PLoS Biology
PLoS Biology, Vol 6, Iss 12, p e319 (2008)
PLoS Biology, Vol 6, Iss 12, p e319 (2008)
It was recently reported that the production of Reactive Oxygen Species (ROS) is a common mechanism of cell death induced by bactericidal antibiotics. Here we show that triggering the Escherichia coli chromosomal toxin–antitoxin system mazEF is an
Publikováno v:
Journal of Bacteriology. 185:1803-1807
As early as 1954, Cohen and Barner discovered that a thymine auxotrophic (thyA) mutant of Escherichia coli undergoes cell death in response to thymine starvation (10). This phenomenon, called thymineless death (TLD) (7), has also been found in many o
Publikováno v:
Journal of bacteriology. 186(11)
mazEF is an Escherichia coli suicide module specific for a stable toxin and a labile antitoxin. Inhibiting mazEF expression appeared to activate the module to cause cell death. Here we show that several stressful conditions, including high temperatur
Publikováno v:
Trends in microbiology. 12(2)
Growing experimental evidence has revealed the existence of programmed cell death (PCD) systems in bacteria. Among these is the mazEF system, which is a regulable suicide module located on the chromosome of E. coli and of some other bacteria, includi
“Addiction modules” consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. The extrachromosomal addiction module phd-doc , located on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21984dc3359acb085b71470ae8bf917e
https://europepmc.org/articles/PMC95101/
https://europepmc.org/articles/PMC95101/
Publikováno v:
Journal of bacteriology. 183(6)
The discovery of toxin-antitoxin gene pairs (also called addiction modules) on extrachromosomal elements of Escherichia coli , and particularly the discovery of homologous modules on the bacterial chromosome, suggest that a potential for programmed c