Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Bo-hyun Choi"'
Autor:
Yun Pyo Kang, Aimee Falzone, Min Liu, Paloma González-Sánchez, Bo-Hyun Choi, Jonathan L. Coloff, James J. Saller, Florian A. Karreth, Gina M. DeNicola
Publikováno v:
Cancer & Metabolism, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Background d-3-phosphoglycerate dehydrogenase (PHGDH), which encodes the first enzyme in serine biosynthesis, is overexpressed in human cancers and has been proposed as a drug target. However, whether PHGDH is critical for the proliferation
Externí odkaz:
https://doaj.org/article/10e50bc8495c4a54bb2a375c109217bd
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Cancer stem cells (CSCs) exhibit intrinsic therapy/stress resistance, which often cause cancer recurrence after therapy. In this study, we investigated the potential relationship between the cluster of differentiation (CD)-133, a CSC marker of colon
Externí odkaz:
https://doaj.org/article/1f0b1ac739704af0a6d2816c4bb15700
Publikováno v:
Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography. 41:93-98
Publikováno v:
Microorganisms, Vol 10, Iss 3, p 650 (2022)
Isoprenoids, which are natural compounds with diverse structures, possess several biological activities that are beneficial to humans. A major consideration in isoprenoid production in microbial hosts is that the accumulation of biosynthesized isopre
Externí odkaz:
https://doaj.org/article/e2f7f93952b24531bc12f83e81176f91
Publikováno v:
Redox Biology, Vol 17, Iss , Pp 246-258 (2018)
Cluster of differentiation 44 (CD44) is the most common cancer stem cell (CSC) marker and high CD44 expression has been associated with anticancer drug resistance, tumor recurrence, and metastasis. In this study, we aimed to investigate the molecular
Externí odkaz:
https://doaj.org/article/aea511e8902f44c3b302955ddd9ab6cc
High Levels of Hyaluronic Acid Synthase-2 Mediate NRF2-Driven Chemoresistance in Breast Cancer Cells
Publikováno v:
Biomolecules & Therapeutics. 30:368-379
Hyaluronic acid (HA), a ligand of CD44, accumulates in some types of tumors and is responsible for tumor progression. The nuclear factor erythroid 2-like 2 (NRF2) regulates cytoprotective genes and drug transporters, which promotes therapy resistance
Autor:
Bo Hyun Choi, Hee Jin Hwang, Ji Eun Lee, Soon Hwan Oh, Jae Sung Hwang, Bun Yeoul Lee, Pyung Cheon Lee
Publikováno v:
Antioxidants, Vol 9, Iss 11, p 1130 (2020)
Chemically synthesized retinyl palmitate has been widely used in the cosmetic and biotechnology industry. In this study, we aimed to demonstrate the microbial production of retinyl palmitate and the benefits of microbial retinyl palmitate in skin phy
Externí odkaz:
https://doaj.org/article/1e29ac9bb1dd4e04b435afdc3d5fefe4
Publikováno v:
Biotechnology and Bioprocess Engineering. 26:776-785
Publikováno v:
Molecules, Vol 19, Iss 8, Pp 12727-12759 (2014)
Chronic kidney disease (CKD) is featured by a progressive decline of kidney function and is mainly caused by chronic diseases such as diabetes mellitus and hypertension. CKD is a complex disease due to cardiovascular complications and high morbidity;
Externí odkaz:
https://doaj.org/article/680c4bef0b354b3e8de32b0797eccf22
Publikováno v:
Archives of Pharmacal Research. 44:263-280
The transcription factor nuclear factor erythroid 2-like 2 (NEF2L2; NRF2) plays crucial roles in the defense system against electrophilic or oxidative stress by upregulating an array of genes encoding antioxidant proteins, electrophile/reactive oxyge