Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Bo-Kyoung Jung"'
1
Akademický článek
The artificial amino acid change in the sialic acid-binding domain of the hemagglutinin neuraminidase of newcastle disease virus increases its specificity to HCT 116 colorectal cancer cells and tumor suppression effect
Autor: Bo-Kyoung Jung, Yong Hee An, Sung Hoon Jang, Jin-Ju Jang, Seonhee Kim, Joo Hee Jeon, Jinju Kim, Jason Jungsik Song, Hyun Jang
Publikováno v: Virology Journal, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Background Oncolytic viruses are being studied and developed as novel cancer treatments. Using directed evolution technology, structural modification of the viral surface protein increases the specificity of the oncolytic virus for a particu
Externí odkaz: https://doaj.org/article/09dcf144bf9d461ca24438b7ee828e63
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2
Akademický článek
The tumor suppressive effect and apoptotic mechanism of TRAIL gene‐containing recombinant NDV in TRAIL‐resistant colorectal cancer HT‐29 cells and TRAIL‐nonresistant HCT116 cells, with each cell bearing a mouse model
Autor: Bo‐Kyoung Jung, Yong Hee An, Sung Hoon Jang, Gyoungah Ryu, Saet‐byel Jung, Seonhee Kim, Cuk‐Seong Kim, Hyun Jang
Publikováno v: Cancer Medicine, Vol 12, Iss 20, Pp 20380-20395 (2023)
Abstract Background TRAIL is an anticancer drug that induces cancer cell apoptosis by interacting with death receptors (DRs). However, owing to low cell‐surface expression of DRs, certain colorectal cancer (CRC) cells resist TRAIL‐induced apoptos
Externí odkaz: https://doaj.org/article/28d148d00a424ef3bcbd183e7b7ec3e4
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3
Akademický článek
The phosphatase and tensin homolog gene inserted between NP and P gene of recombinant New castle disease virus oncolytic effect test to glioblastoma cell and xenograft mouse model
Autor: Sung Hoon Jang, Bo-Kyoung Jung, Yong Hee An, Hyun Jang
Publikováno v: Virology Journal, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background Glioblastoma is one of the most serious brain cancer. Previous studies have demonstrated that PTEN function disorder affects the causing and exacerbation of glioblastoma. Newcastle disease virus (NDV) has been studied as a cancer
Externí odkaz: https://doaj.org/article/4d30f130d672484da1905b13b1312e54
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4
Akademický článek
The human ACE-2 receptor binding domain of SARS-CoV-2 express on the viral surface of the Newcastle disease virus as a non-replicating viral vector vaccine candidate
Autor: Bo-Kyoung Jung, Yong Hee An, Jin-Ju Jang, Joo Hee Jeon, Sung Hoon Jang, Hyun Jang
Publikováno v: PLoS ONE, Vol 17, Iss 2 (2022)
Since the SARS-CoV-2 infection was identified in December 2019, SARS-CoV-2 infection has rapidly spread worldwide and has become a significant pandemic disease. In addition, human death and serious health problem caused by SARS-CoV-2 infection, the s
Externí odkaz: https://doaj.org/article/9600948815d64e429ba5acb0d6b5c49b
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5
Akademický článek
Inhibition of lipid accumulation by the ethyl acetate fraction of Distylium racemosum in vitro and in vivo
Autor: Hye-Ran Kim, Bo-Kyoung Jung, Min-Ho Yeo, Weon-Jong Yoon, Kyung-Soo Chang
Publikováno v: Toxicology Reports, Vol 6, Iss , Pp 215-221 (2019)
This study confirms the anti-obesity effect of the ethyl acetate fraction of Distylium racemosum (DRE), a member of Hamamelidaceae, that naturally grows on Jeju Island, on adipocyte differentiation in 3T3-L1 cells. This study further demonstrated tha
Externí odkaz: https://doaj.org/article/200938ccd4164271a748935a8adab7a8
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6
Development of a recombinant vaccine containing a spike S1-Fc fusion protein induced protection against MERS-CoV in human DPP4 knockin transgenic mice
Autor: Kyung-Soo Chang, Hyun M. Jang, YongHee An, Jung-Eun Park, Bo-Kyoung Jung
Publikováno v: Journal of Virological Methods
The Middle East respiratory syndrome coronavirus (MERS-CoV), belonging to the family Coronaviridae and genus Betacoronavirus, has been recognized as a highly pathogenic virus. Due to the lack of therapeutic or preventive agents against MERS-CoV, deve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa135d80e2979326810f3356d538ed5
http://europepmc.org/articles/PMC8556695
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7
Inhibition of lipid accumulation by the ethyl acetate fraction of Distylium racemosum in vitro and in vivo
Autor: Weon-Jong Yoon, Bo-Kyoung Jung, Min-Ho Yeo, Hye-Ran Kim, Kyung-Soo Chang
Publikováno v: Toxicology Reports, Vol 6, Iss, Pp 215-221 (2019)
Toxicology Reports
Highlights • Lipid accumulation in the 3T3-L1 cells were inhibited by treatment with DRE. • The expression levels of SREBP1c, PPARγ, C/EBPα, and FAS were decreased by DRE. • HFD induced fat mice showed lower rate of weight gain and serum TG l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c428babe5dc656bd3c109939c6d6982b
http://www.sciencedirect.com/science/article/pii/S2214750018303731
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9
Comparison of Immune Responses to the PCV2 Replicase-Capsid and Capsid Virus-Like Particle Vaccines in Mice
Autor: Hyun M. Jang, Kyung-Soo Chang, Bo-Kyoung Jung, Young-Hyeon Lee, Hye-Ran Kim
Publikováno v: Journal of microbiology and biotechnology. 29(3)
Porcine circovirus type 2 (PCV2) is the causative agent of postweaning multisystemic wasting syndrome (PMWS) in pigs. Replicase (Rep) proteins are considered essential for viral replication. Capsid (Cap) protein is the primary immunogenic protein tha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8678cafb8618e9dc26c41e9ea3b9fd6
https://pubmed.ncbi.nlm.nih.gov/30609882
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