Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Bo-Hyun Choi"'
Autor:
Yun Pyo Kang, Aimee Falzone, Min Liu, Paloma González-Sánchez, Bo-Hyun Choi, Jonathan L. Coloff, James J. Saller, Florian A. Karreth, Gina M. DeNicola
Publikováno v:
Cancer & Metabolism, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Background d-3-phosphoglycerate dehydrogenase (PHGDH), which encodes the first enzyme in serine biosynthesis, is overexpressed in human cancers and has been proposed as a drug target. However, whether PHGDH is critical for the proliferation
Externí odkaz:
https://doaj.org/article/10e50bc8495c4a54bb2a375c109217bd
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Cancer stem cells (CSCs) exhibit intrinsic therapy/stress resistance, which often cause cancer recurrence after therapy. In this study, we investigated the potential relationship between the cluster of differentiation (CD)-133, a CSC marker of colon
Externí odkaz:
https://doaj.org/article/1f0b1ac739704af0a6d2816c4bb15700
Publikováno v:
Redox Biology, Vol 17, Iss , Pp 246-258 (2018)
Cluster of differentiation 44 (CD44) is the most common cancer stem cell (CSC) marker and high CD44 expression has been associated with anticancer drug resistance, tumor recurrence, and metastasis. In this study, we aimed to investigate the molecular
Externí odkaz:
https://doaj.org/article/aea511e8902f44c3b302955ddd9ab6cc
Publikováno v:
Molecules, Vol 19, Iss 8, Pp 12727-12759 (2014)
Chronic kidney disease (CKD) is featured by a progressive decline of kidney function and is mainly caused by chronic diseases such as diabetes mellitus and hypertension. CKD is a complex disease due to cardiovascular complications and high morbidity;
Externí odkaz:
https://doaj.org/article/680c4bef0b354b3e8de32b0797eccf22
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153965 (2016)
Chronic kidney disease (CKD) is a major complication of metabolic disorders such as diabetes mellitus, obesity, and hypertension. Comorbidity of these diseases is the factor exacerbating CKD progression. Statins are commonly used in patients with met
Externí odkaz:
https://doaj.org/article/f5da78a36861413da1ef9efe9fd3771f
Autor:
Min-Gu Song, In-Geun Ryoo, Hye-Young Choi, Bo-Hyun Choi, Sang-Tae Kim, Tae-Hwe Heo, Joo Young Lee, Pil-Hoon Park, Mi-Kyoung Kwak
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134235 (2015)
Blood monocytes are recruited to injured tissue sites and differentiate into macrophages, which protect against pathogens and repair damaged tissues. Reactive oxygen species (ROS) are known to be an important contributor to monocytes' differentiation
Externí odkaz:
https://doaj.org/article/73da25c6aa3c4b4d8f8e50dc02c343a6
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107158 (2014)
Photodynamic therapy (PDT) has emerged as an effective treatment for various solid tumors. The transcription factor NRF2 is known to protect against oxidative and electrophilic stress; however, its constitutive activity in cancer confers resistance t
Externí odkaz:
https://doaj.org/article/a993afdfec4745d980dcae49bc9e9363
Publikováno v:
Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography. 41:93-98
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6161fe37307f38a0d7910416b6065b99
https://doi.org/10.7848/ksgpc.2023.41.2.93
https://doi.org/10.7848/ksgpc.2023.41.2.93
Publikováno v:
Catalysts, Vol 11, Iss 10, p 1248 (2021)
Phytoene desaturase (CrtI, E.C. 1.3.99.31) shows variable desaturation activity, thereby introducing different numbers of conjugated double bonds (CDB) into the substrate phytoene. In particular, Rhodobacter sphaeroides CrtI is known to introduce add
Externí odkaz:
https://doaj.org/article/2751ec53216d489f9e05b7e66a9a4abc
High Levels of Hyaluronic Acid Synthase-2 Mediate NRF2-Driven Chemoresistance in Breast Cancer Cells
Publikováno v:
Biomolecules & Therapeutics. 30:368-379
Hyaluronic acid (HA), a ligand of CD44, accumulates in some types of tumors and is responsible for tumor progression. The nuclear factor erythroid 2-like 2 (NRF2) regulates cytoprotective genes and drug transporters, which promotes therapy resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4253c3f8a0c5ad529bb0bb4fdaf8907d
https://doi.org/10.4062/biomolther.2022.074
https://doi.org/10.4062/biomolther.2022.074