Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Bo-Hwa Sohn"'
Autor:
Yun Seong Jeong, Young-Gyu Eun, Sung Hwan Lee, Sang-Hee Kang, Sun Young Yim, Eui Hyun Kim, Joo Kyung Noh, Bo Hwa Sohn, Seon Rang Woo, Moonkyoo Kong, Deok Hwa Nam, Hee-Jin Jang, Hyun-Sung Lee, Shumei Song, Sang Cheul Oh, Jeeyun Lee, Jaffer A. Ajani, Ju-Seog Lee
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-17 (2023)
Abstract Gastric adenocarcinoma (GAC) is a lethal disease characterized by genomic and clinical heterogeneity. By integrating 8 previously established genomic signatures for GAC subtypes, we identified 6 clinically and molecularly distinct genomic co
Externí odkaz:
https://doaj.org/article/ccfad52390c4482ca6467186cf9c2361
Autor:
Sung Hwan Lee, Yun Seong Jeong, Sunyoung Lee, Bo Hwa Sohn, Ho Kyoung Hwang, Gi Hong Choi, Chang Moo Kang, Jin Sub Choi, Woo Jung Lee, Jae‐Ho Cheong, Hee Jin Jang, Ahmed Kaseb, Lewis Roberts, Sun Young Yim, Yun Shin Chun, Ju‐Seog Lee
Publikováno v:
Cancer Communications, Vol 42, Iss 2, Pp 179-183 (2022)
Externí odkaz:
https://doaj.org/article/91ef7777a8c54618b418d09773ba857d
Autor:
Min‐Kyue Shin, Jungmin Kim, Dachan Kim, Sung Hwan Lee, Ji‐Hyun Shin, Yun Seong Jeong, Bo Hwa Sohn, Jimin Kim, Seong‐Ryong Kim, Jaffer A. Ajani, Ju‐Seog Lee, Jae‐Ho Cheong
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 6, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/9bfab09c645a4f4e9d6547ce82320e3e
Autor:
Sang Cheul Oh, Bo Hwa Sohn, Jae-Ho Cheong, Sang-Bae Kim, Jae Eun Lee, Ki Cheong Park, Sang Ho Lee, Jong-Lyul Park, Yun-Yong Park, Hyun-Sung Lee, Hee-Jin Jang, Eun Sung Park, Sang-Cheol Kim, Jeonghoon Heo, In-Sun Chu, You-Jin Jang, Young-Jae Mok, WonKyung Jung, Baek-Hui Kim, Aeree Kim, Jae Yong Cho, Jae Yun Lim, Yuki Hayashi, Shumei Song, Elena Elimova, Jeannelyn S. Estralla, Jeffrey H. Lee, Manoop S. Bhutani, Yiling Lu, Wenbin Liu, Jeeyun Lee, Won Ki Kang, Sung Kim, Sung Hoon Noh, Gordon B. Mills, Seon-Young Kim, Jaffer A. Ajani, Ju-Seog Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The prognosis and treatment of gastric cancer is complicated by heterogeneity. Here, the authors reveal two molecular subtypes, the mesenchymal subtype associated with poor survival and chemoresistance, and the epithelial phenotype associated with be
Externí odkaz:
https://doaj.org/article/cb4f389472124edeb3126b20dcd9ed15
Autor:
Chan-Young Ock, Jun-Eul Hwang, Bhumsuk Keam, Sang-Bae Kim, Jae-Jun Shim, Hee-Jin Jang, Sarang Park, Bo Hwa Sohn, Minse Cha, Jaffer A. Ajani, Scott Kopetz, Keun-Wook Lee, Tae Min Kim, Dae Seog Heo, Ju-Seog Lee
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
There is an urgent need to identify predictive markers for selecting responders to immunotherapy. Here, the authors describe a transcriptional predictor of immunotherapy response and assess it in genomic data from ~ 10,000 human tissues across 30 dif
Externí odkaz:
https://doaj.org/article/6a7dbe118f55479d9642734712ad0d61
Autor:
Sung Hwan Lee, Sun Young Yim, Yun Seong Jeong, Qi‐Xiang Li, Sang‐Hee Kang, Bo Hwa Sohn, Shwetha V. Kumar, Ji‐Hyun Shin, You Rhee Choi, Jae‐Jun Shim, Hayeon Kim, Ji Hoon Kim, Shin Kim, Sheng Guo, Randy L. Johnson, Ahmed Kaseb, Koo Jeong Kang, Yun Shin Chun, Hee Jin Jang, Byoung Gill Lee, Hyun Goo Woo, Min Jin Ha, Rehan Akbani, Lewis R. Roberts, David A. Wheeler, Ju‐Seog Lee
Publikováno v:
Hepatology. 76:1634-1648
Although many studies revealed transcriptomic subtypes of HCC, concordance of the subtypes are not fully examined. We aim to examine a consensus of transcriptomic subtypes and correlate them with clinical outcomes.By integrating 16 previously establi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce1378552daf75d0241bc1992496444e
https://doi.org/10.1002/hep.32490
https://doi.org/10.1002/hep.32490
Autor:
W. Kimryn Rathmell, Cheryl L. Walker, Ruhee Dere, Joel S. Parker, Brian D. Strahl, Ian J. Davis, Abid Khan, Aguirre A. de Cubas, Yihsuan S. Tsai, Ryoma Ohi, Reid T. Powell, Pratim Chowdhury, Bo-Hwa Sohn, Charles B. Shuster, Menuka Karki, Catherine C. Fahey, Frank M. Mason, Durga Nand Tripathi, Esteban A. Terzo, In-Young Park, Yun-Chen Chiang
Multiple Setd2w/f MEF clones display reduced aTubK40me3 protein (A) and relative Setd2 mRNA (B) levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68330e57b1526582bc9f5ed1c815878b
https://doi.org/10.1158/0008-5472.22419720.v1
https://doi.org/10.1158/0008-5472.22419720.v1
Autor:
Ju-Seog Lee, Sang Cheul Oh, Sung Soo Kim, Scott Kopetz, Yun-Yong Park, Hee-Jin Jang, Hyun-Sung Lee, Bo Hwa Sohn, Sang-Bae Kim, Sung Sook Lee, Keun-Wook Lee
Purpose: Activation of YAP1, a novel oncogene in the Hippo pathway, has been observed in many cancers, including colorectal cancer. We investigated whether activation of YAP1 is significantly associated with prognosis or treatment outcomes in colorec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76777c5d26639629262387df0dd05109
https://doi.org/10.1158/1078-0432.c.6524390
https://doi.org/10.1158/1078-0432.c.6524390
Autor:
Ju-Seog Lee, Sang Cheul Oh, Sung Soo Kim, Scott Kopetz, Yun-Yong Park, Hee-Jin Jang, Hyun-Sung Lee, Bo Hwa Sohn, Sang-Bae Kim, Sung Sook Lee, Keun-Wook Lee
Supplementary Figures S1-S5. Supplementary Figure S1. Expression of YAP1 in NCI-H716 CRC cells. Supplementary Figure S2. YAP1-specific gene expression signature used in our study of YAP1 activation in CRC patients. Supplementary Figure S3. Gene set e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2b7f941c7fcb1ef832f50ff91b3c61
https://doi.org/10.1158/1078-0432.22460066
https://doi.org/10.1158/1078-0432.22460066
Autor:
Ju-Seog Lee, Yun-Yong Park, Randy L. Johnson, In-Sun Chu, Minse Cha, Manal M. Hassan, Ahmed Kaseb, Sun-Hee Leem, Dae-Ghon Kim, Yoon Jun Kim, Jeonghoon Heo, Eun Sung Park, Sung Soo Kim, Woojin Jeong, Sang-Cheol Kim, Hyun-Sung Lee, Hee-Jin Jang, Jun Eul Hwang, Ji Hoon Kim, Soo Mi Kim, Kyu Yun Jang, Sang-Bae Kim, Jae-Jun Shim, Bo Hwa Sohn
Purpose: The Hippo pathway is a tumor suppressor in the liver. However, the clinical significance of Hippo pathway inactivation in HCC is not clearly defined. We analyzed genomic data from human and mouse tissues to determine clinical relevance of Hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7acad76488aad67848e1f80058140eb1
https://doi.org/10.1158/1078-0432.c.6523584.v1
https://doi.org/10.1158/1078-0432.c.6523584.v1