Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Bo-Chul Shin"'
Autor:
Xin Ye, Shubhamoy Ghosh, Bo-Chul Shin, Amit Ganguly, Liesbeth Maggiotto, Jonathan P. Jacobs, Sherin U. Devaskar
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionSerotonin (5-HT) is critical for neurodevelopment and the serotonin transporter (SERT) modulates serotonin levels. Perturbed prenatal and postnatal dietary exposures affect the developing offspring predisposing to neurobehavioral disorder
Externí odkaz:
https://doaj.org/article/719f5033147341eca5139c60f310502c
Publikováno v:
Nutrients, Vol 16, Iss 14, p 2363 (2024)
Glucose is the primary energy source for most mammalian cells and its transport is affected by a family of facilitative glucose transporters (GLUTs) encoded by the SLC2 gene. GLUT1 and GLUT3, highly expressed isoforms in the blood–brain barrier and
Externí odkaz:
https://doaj.org/article/0c504b643e3845eda76895721f5e54ba
Autor:
Liesbeth V. Maggiotto, Shubhamoy Ghosh, Bo-Chul Shin, Amit Ganguly, Venu Lagishetty, Jonathan P. Jacobs, Sherin U. Devaskar
Publikováno v:
Nutrients, Vol 15, Iss 1, p 217 (2023)
Intra-Uterine Growth Restriction (IUGR) is a risk factor for many adult-onset chronic diseases, such as diabetes and obesity. These diseases are associated with intestinal microbiome perturbations (dysbiosis). The establishment of an intestinal micro
Externí odkaz:
https://doaj.org/article/adaabdfe1ff64e088a47bc793e2c812a
Autor:
Carla Janzen, Margarida Y Y Lei, Il Seok D Jeong, Amit Ganguly, Peggy Sullivan, Vladislava Paharkova, Gina Capodanno, Hiromi Nakamura, Alix Perry, Bo-Chul Shin, Kuk-Wha Lee, Sherin U Devaskar
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193583 (2018)
Intrauterine growth restriction (IUGR) results from a lack of nutrients transferred to the developing fetus, particularly oxygen and glucose. Increased expression of the cytoprotective mitochondrial peptide, humanin (HN), and the glucose transporter
Externí odkaz:
https://doaj.org/article/4d7a940141884c81a716a9c8f0eff9d4
Publikováno v:
Developmental neuroscience, vol 43, iss 1
Dev Neurosci
Dev Neurosci
Perturbed maternal diet and prenatal exposure to air pollution (AP) affect the fetal brain, predisposing to postnatal neurobehavioral disorders. Glucose transporters (GLUTs) are key in fueling neurotransmission; deficiency of the neuronal isoform GLU
Publikováno v:
Nutr Res
Diet during pregnancy has long lasting consequences on the offspring, warranting a study on the impact of early exposure to a high fat diet on the adult offspring. We hypothesized that a prenatal n-6 enriched diet will have adverse metabolic outcomes
Autor:
Shanthie Thamotharan, Sherin U. Devaskar, Satish C. Kalhan, Kara L. Calkins, Bo-Chul Shin, Yun Dai
Publikováno v:
Nutrition Research. 54:93-104
Intrauterine growth restriction is linked to decreased lean body mass and insulin resistance. The mammalian target of rapamycin (mTOR) regulates muscle mass and glucose metabolism; however, little is known about maternal dietary restriction and skele
Autor:
Andrew Frew, Shanthie Thamotharan, Jingjing Zhang, Bo-Chul Shin, Carlos Cepeda, Jeffry R. Alger, Yun Dai, Sudatip Kositamongkol, Michael S. Levine, Yuanzi Zhao, Monica Sondhi, Raman Sankar, Andrey Mazarati, Sherin U. Devaskar, Peter M. Clark, Masatoshi Tomi, Elizabeth A. Wang, Leah Leibovitch
Publikováno v:
Endocrinology. 158:936-949
We tested the hypothesis that exposure of glut3+/− mice to a ketogenic diet ameliorates autism-like features, which include aberrant behavior and electrographic seizures. We first investigated the life course sex-specific changes in basal plasma–
Publikováno v:
Molecular genetics and metabolism, vol 127, iss 2
Mol Genet Metab
Mol Genet Metab
OBJECTIVE: We examined Red Blood Cell (RBC) Glucose Transporter isoform 1 (GLUT1) and White Blood Cell (WBC) Glucose Transporter isoform 3 (GLUT3) protein concentrations to assess their potential as surrogate biomarkers for the presence of hypoxic-is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbfc52c822c8b34392f7ec9b6dc6f33
https://escholarship.org/uc/item/7330528b
https://escholarship.org/uc/item/7330528b
Autor:
Michael Levine, Shin Yun Byun, Carlos Cepeda, Mason Eghbali, Bo-Chul Shin, Sherin U. Devaskar
Publikováno v:
Exp Neurol
Since GLUT3 is vital for fueling neurotransmission, we examined in-vivo the adult phenotype carrying the conditional homozygous glut3 gene mutation (KO) in glutamate-excitatory neurons. These KO mice demonstrated sex-specific differences in brain and