Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Bo-Chin Chiu"'
Publikováno v:
The Journal of Immunology. 191:5793-5796
The number of memory phenotype CD8 T cells increases dramatically with aging in both humans and mice. However, the mechanism for this is unknown. The prevailing hypothesis is that memory T cells accumulate with aging as a result of lifelong antigenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc31dbf9527ffadadd7867aa249a65f0
https://doi.org/10.4049/jimmunol.1302509
https://doi.org/10.4049/jimmunol.1302509
Autor:
Matyas Sandor, Steven L. Kunkel, Brian M. Schmidt, Bo Chin Chiu, Stephen W. Chensue, Valerie R. Stolberg
Publikováno v:
The American Journal of Pathology. 178:233-244
Cysteine-cysteinyl chemokine receptor 4 (CCR4) is expressed by a variety of T-cell subsets and leukocytes. This study examined the participation of CCR4 in response to pulmonary infection with Mycobacterium bovis Bacille-Calmette-Guerin (BCG). Consti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd17875bd2a5cb923309fbbe373018d
https://doi.org/10.1016/j.ajpath.2010.11.036
https://doi.org/10.1016/j.ajpath.2010.11.036
Publikováno v:
Open Longevity Science (Formerly 'The Open Aging Journal'). 1:1-7
Impaired pulmonary immunity in the aged is poorly understood. Lymph node recirculation of CD4+ T cells is important for adaptive immunity and depends on CD62L and CCR7. We compared circulatory capacity of CD4+ T cells from young and aged mice in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29960b82a14c09ffbb856a26ba16ff9
https://doi.org/10.2174/1876326x00701010001
https://doi.org/10.2174/1876326x00701010001
Publikováno v:
Mechanisms of Ageing and Development. 128:618-627
As potent suppressors of immune responses to self- and foreign-antigens, Foxp3+ Treg cells are suspected to be involved in immunosuppression leading to cancer, neurodegeneration and infection. Since ageing is associated with increased incidence of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e640ebc5c0846face9a227f0321272f8
https://doi.org/10.1016/j.mad.2007.09.002
https://doi.org/10.1016/j.mad.2007.09.002
Autor:
Steven L. Kunkel, Valerie R. Stolberg, Christine M. Freeman, Bo Chin Chiu, Stephen W. Chensue, Nicholas W. Lukacs
Publikováno v:
The Journal of Immunology. 177:4149-4158
CCR4 is purported to be a Th type 2 (Th2) cell-biased receptor but its functional role is unclear. Recent studies suggest that chemokine receptor expression and function are more complex in vivo and raise doubts regarding restricted CCR4 expression b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229eb0724921d1796366ebcc8b3bad12
https://doi.org/10.4049/jimmunol.177.6.4149
https://doi.org/10.4049/jimmunol.177.6.4149
Publikováno v:
Cellular Immunology. 237:45-54
The contribution of inducible costimulatory molecule (ICOS) to Th1 and Th2 cell-mediated immune responses was examined in well-defined pathogen antigen-elicited models of cell-mediated granuloma formation. Th1 and Th2 granulomas were respectively ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d72df05f53f29c55203492c098032de0
https://doi.org/10.1016/j.cellimm.2005.09.005
https://doi.org/10.1016/j.cellimm.2005.09.005
Autor:
Stephen W. Chensue, Kyriaki Zeibecoglou, Israel F. Charo, Craig Gerard, Sergio A. Lira, Jerry S. Hu, Bao Lu, Christine M. Freeman, Bo Chin Chiu, Valerie R. Stolberg
Publikováno v:
The American Journal of Pathology. 165:1199-1209
Dendritic cell (DC) recruitment is a hallmark event in antigen (Ag)-challenged lungs. We previously reported models for analyzing DC migration and activation in the lung after Th1- or Th2-eliciting pathogen Ag-bead challenge. To determine the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb85df2367f0f7d0b037740d7a1cce20
https://doi.org/10.1016/s0002-9440(10)63380-9
https://doi.org/10.1016/s0002-9440(10)63380-9
Autor:
Valerie R. Stolberg, Eric Komuniecki, Stephen W. Chensue, Bo Chin Chiu, Jerry S. Hu, Christine M. Freeman
Publikováno v:
The American Journal of Pathology. 164:1021-1030
Granulomas are innate sequestration responses that can be modified by superimposed acquired immune mechanisms. The present study examined the innate stage of pulmonary granuloma responses to bead-immobilized Th1- and Th2-inducing pathogen antigens (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02c014f446c062c8336705259b1e1ac8
https://doi.org/10.1016/s0002-9440(10)63189-6
https://doi.org/10.1016/s0002-9440(10)63189-6
Publikováno v:
Journal of Leukocyte Biology. 72:363-372
Chemokine receptor transcripts were de- fined among CD4 T cells in lymph nodes of mice with type-1 and type-2 inflammation, respectively, elicited by mycobacterial and schistosomal Ag. CXCR3 and CCR6 transcripts were biased to type-1, and CCR4 transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98887fb1d5db3e2d7854081ab8491a8e
https://doi.org/10.1189/jlb.72.2.363
https://doi.org/10.1189/jlb.72.2.363
Autor:
Bo Chin Chiu, Steven L. Kunkel, Valerie R. Stolberg, Xiao Zhou Shang, Nicholas W. Lukacs, Stephen W. Chensue, Hedwig S. Murphy
Publikováno v:
The American Journal of Pathology. 161:257-266
Monocyte chemotactic protein-3 (MCP-3/CCL7) has potent eosinophil chemoattractant properties. The present study determined its relative contribution to the formation of Th2 cytokine-mediated (type-2) eosinophil-rich interstitial lung granulomas induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af3bd8f17e7e3ec1bf25d1a5c23712ca
https://doi.org/10.1016/s0002-9440(10)64177-6
https://doi.org/10.1016/s0002-9440(10)64177-6