Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Bo-Chen Zhu"'
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 39, Iss 8, Pp 769-778 (2023)
Abstract Atopic dermatitis (AD) is a chronic and recurrent inflammatory skin disease. Keratinocyte dysfunction plays a central role in AD development. MicroRNA is a novel player in many inflammatory and immune skin diseases. In this study, we investi
Externí odkaz:
https://doaj.org/article/9e95f969577944989b05d9f90abbb8ff
Publikováno v:
The Kaohsiung Journal of Medical Sciences.
Autor:
Bo-Chen Zhu, Juan He, Xiao-Yu Xia, Jingxing Jiang, Wenting Liu, Liu-Yi Liu, Bing-Bing Liang, Hua-Gang Yao, Zhuofeng Ke, Wei Xia, Zong-Wan Mao
Publikováno v:
Chemical Science. 13:8371-8379
A quasi-cross-shaped platinum(II) compound (L′2LPt) with inhibitory activity against thrombin binds the antiparallel two-G-tetrad G-quadruplex TBA. The NMR structure of the Pt–G-quadruplex was solved to reveal this unusual “wall-mounted” bind
Autor:
Xiao-Yu Xia, Juan He, Bing Liu, Liang-Nian Ji, Liu-Yi Liu, Hua-Gang Yao, Bo-Chen Zhu, Zong-Wan Mao, Wenting Liu, Bing-Bing Liang
Publikováno v:
Angewandte Chemie. 133:15468-15471
G-quadruplexes (G4s) are prevalent in oncogenes and proposed to be potential antitumor drug targets. However, binding selectivity of compounds to G4s still faces challenges. Herein, we report a platinum(II) complex ( Pt1 ), whose affinity to G4-DNA i
Publikováno v:
Nucleic acids research. 50(14)
G-quadruplex (G4) transitions play integral roles in regulating biological functions and can be modified by ligands. However, little is known about G4 transitions. Herein, we reveal distinct pathways of a platinum(II) compound Pt-phen converting para
Publikováno v:
Angewandte Chemie. 132:9806-9813
G-quadruplex DNA show structural polymorphism, leading to challenges in the use of selective recognition probes for the accurate detection of G-quadruplexes in vivo. Herein, we present a tripodal cationic fluorescent probe, NBTE, which showed disting