Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Bo van Deurs"'
Autor:
Bodil Vistisen, Kirstine Roepstorff, Carsten Roepstorff, Arend Bonen, Bo van Deurs, Bente Kiens
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 4, Pp 603-609 (2004)
FAT/CD36 is a transmembrane protein that is thought to facilitate cellular long-chain fatty acid uptake. However, surprisingly little is known about the localization of FAT/CD36 in human skeletal muscle. By confocal immunofluorescence microscopy, we
Externí odkaz:
https://doaj.org/article/1974f0ed27d64435a79cfbc4e6df6060
Autor:
Lasse Henriksen, Michael Vibo Grandal, Stine Louise Jeppe Knudsen, Bo van Deurs, Lene Melsæther Grøvdal
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58148 (2013)
The epidermal growth factor receptor (EGFR) regulates normal growth and differentiation, but dysregulation of the receptor or one of the EGFR ligands is involved in the pathogenesis of many cancers. There are eight ligands for EGFR, however most of t
Externí odkaz:
https://doaj.org/article/01abcb519a2d448e9003a052150ee79a
Autor:
Audrun Utskarpen, Ramiro Massol, Bo van Deurs, Silje Ugland Lauvrak, Tomas Kirchhausen, Kirsten Sandvig
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e10944 (2010)
Clathrin-dependent endocytosis is a main entry mechanism for the glycolipid-binding Shiga toxin (Stx), although clathrin-independent pathways are also involved. Binding of Stx to its receptor Gb3 not only is essential for Stx retrograde transport to
Externí odkaz:
https://doaj.org/article/55f11ac3b5fb41bf94dc9cf0ef2b096c
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8844 (2010)
The flotillin proteins are localized in lipid domains at the plasma membrane as well as in intracellular compartments. In the present study, we examined the importance of flotillin-1 and flotillin-2 for the uptake and transport of the bacterial Shiga
Externí odkaz:
https://doaj.org/article/3d511d659c5445b1a82700d2d10facd7
Publikováno v:
Experimental cell research. 357(1)
Benzyl alcohol (BnOH) is widely used as a component of foods, cosmetics, household products and medical products. It is generally considered to be safe for human use, however, it has been connected to a number of adverse effects, including hypersensi
Autor:
Reidar Albrechtsen, Michael Vibo Grandal, Marie Kveiborg, Dorte Stautz, Ulla M. Wewer, Anthony Leyme, Bo van Deurs
Publikováno v:
Traffic. 13:1532-1546
ADAM12 (A Disintegrin And Metalloprotease 12), a member of the ADAMs family of transmembrane proteins, is involved in ectodomain shedding, cell-adhesion and signaling, with important implications in cancer. Therefore, mechanisms that regulate the lev
Autor:
Patrick Ejlerskov, Dan Ploug Christensen, Frederik Vilhardt, David Beyaie, Agnes Görlach, James B. Burritt, Marie-Hélène Paclet, Bo van Deurs
Publikováno v:
Journal of Biological Chemistry. 287:4835-4852
Here, we report that activation of different types of tissue macrophages, including microglia, by lipopolysaccharide (LPS) or GM-CSF stimulation correlates with the quantitative redistribution of NADPH oxidase (cyt b(558)) from the plasma membrane to
Autor:
Mette H. Andersen, Inger H. Madshus, Lene Melsæther Grøvdal, Michael Vibo Grandal, Mikkel R. Holst, Bo van Deurs, Lasse Henriksen
Publikováno v:
Traffic. 13:576-585
The epidermal growth factor receptor (EGFR) is an important regulator of normal growth and differentiation, and it is involved in the pathogenesis of many cancers. Endocytic downregulation is central in terminatingEGFRsignaling after ligand stimulati
Publikováno v:
Current Opinion in Cell Biology. 23:413-420
It is now about 20 years since we first wrote reviews about clathrin-independent endocytosis. The challenge at the time was to convince the reader about its existence. Then the suggestion came up that caveolae might be responsible for the uptake. How
Autor:
Maria Torp Larsen, Martin Iversen, Marianne H. Jørgensen, Bjarke Askaa, Niels Borregaard, Ole Østergaard, Niels H. H. Heegaard, Sara Rørvig, Lars C. Jacobsen, Bo van Deurs, Stine N. Clemmensen, Karin Christenson, Jack B. Cowland
Publikováno v:
European Journal of Haematology. 86:517-530
Alpha-1-antitrypsin (A1AT) is an important inhibitor of neutrophil proteases including elastase, cathepsin G, and proteinase 3. Transcription profiling data suggest that A1AT is expressed by human neutrophil granulocytes during all developmental stag