Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Bo Xin Zheng"'
Publikováno v:
Chemical Communications. 59:1415-1433
The recent advances in G-quadruplex-selective ligands in the fields of live cell imaging, chemical biology and therapeutic prospects against bacterial infections.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddddb9370aa4c326650e1e6a2f4852d8
https://doi.org/10.1039/d2cc05945b
https://doi.org/10.1039/d2cc05945b
Autor:
Bo‐Xin Zheng, Wei Long, Meng‐Ting She, Yakun Wang, Dong Zhao, Jie Yu, Alan Siu‐Lun Leung, Ka Hin Chan, Jinqiang Hou, Yu‐Jing Lu, Wing‐Leung Wong
Publikováno v:
Chemistry – A European Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::441b57a93a448db76337e5840d10f6fb
https://doi.org/10.1002/chem.202300705
https://doi.org/10.1002/chem.202300705
Autor:
Wei Long, Bo-Xin Zheng, Ying Li, Xuan-He Huang, Dan-Min Lin, Cui-Cui Chen, Jin-Qiang Hou, Tian-Miao Ou, Wing-Leung Wong, Kun Zhang, Yu-Jing Lu
Publikováno v:
Nucleic Acids Research. 50:1829-1848
DNA G4-structures from human c-MYC promoter and telomere are considered as important drug targets; however, the developing of small-molecule-based fluorescent binding ligands that are highly selective in targeting these G4-structures over other types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd6775f06f0cb51c1153088a65bf06d
https://doi.org/10.1093/nar/gkac090
https://doi.org/10.1093/nar/gkac090
Autor:
Ao Lu Liu, Meng Ting She, Wing-Leung Wong, Xuan He Huang, Wei Long, Yu Jing Lu, Bo Xin Zheng, Kun Zhang
Publikováno v:
Journal of Medicinal Chemistry. 64:2125-2138
A series of fluorescent ligands, which were systematically constructed from thiazole orange scaffold, was investigated for their interactions with G-quadruplex structures and antitumor activity. Among the ligands, compound 3 was identified to exhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7072bcda4281468aee57374d93123cfe
https://doi.org/10.1021/acs.jmedchem.0c01656
https://doi.org/10.1021/acs.jmedchem.0c01656
Akademický článek
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Autor:
Meng-Ting She, Jia-Wei Yang, Bo-Xin Zheng, Wei Long, Xuan-He Huang, Jun-Ren Luo, Ze-Xin Chen, Ao-Lu Liu, Dong-Peng Cai, Wing-Leung Wong, Yu-Jing Lu
Publikováno v:
Chemical Engineering Journal. 446:136947
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04985ea151276d4abdf92c045ef39c78
https://doi.org/10.1016/j.cej.2022.136947
https://doi.org/10.1016/j.cej.2022.136947
Autor:
Dong-Xiao Zhong, Meng-Ting She, Xiao-Chun Guo, Bo-Xin Zheng, Xuan-He Huang, Yi-Han Zhang, Hooi-Leng Ser, Wing-Leung Wong, Ning Sun, Yu-Jing Lu
Publikováno v:
European Journal of Medicinal Chemistry. 236:114360
The discovery of small molecular inhibitors targeting essential and conserved bacterial drug targets such as FtsZ protein is a promising approach to fight against multi-drug resistant bacteria. In the present study, two new series of FtsZ inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b010c8de982f617756ca075285d77ee
https://doi.org/10.1016/j.ejmech.2022.114360
https://doi.org/10.1016/j.ejmech.2022.114360
Autor:
Wing-Leung Wong, Meng Ting She, Xuan He Huang, Yu Jing Lu, Wenjie Liu, Yi Han Zhang, Yong Yu Xu, Bo Xin Zheng, Jinqiang Hou, Wei Long
Publikováno v:
Chemical communications (Cambridge, England). 56(95)
A small-sized c-MYC promoter G-quadruplex selective fluorescent BZT-Indolium binding ligand was demonstrated for the first time as a highly target-specific and photostable probe for in vitro staining and live cell imaging and it was found to be able
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06d09f00b7a1bf282a3bcd7555f67aa
https://pubmed.ncbi.nlm.nih.gov/33185205
https://pubmed.ncbi.nlm.nih.gov/33185205