Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Bo Shiun Chen"'
Autor:
Reta Birhanu Kitata, Wai-Kok Choong, Chia-Feng Tsai, Pei-Yi Lin, Bo-Shiun Chen, Yun-Chien Chang, Alexey I. Nesvizhskii, Ting-Yi Sung, Yu-Ju Chen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Phosphoproteomics can provide systematic insights into disease-associated cell signaling changes. Here, the authors present a sensitive workflow integrating library-based and direct data-independent acquisition approaches, and a hybrid spectral libra
Externí odkaz:
https://doaj.org/article/86260f2d4cfc4d5badf02ec996ec67af
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/0fd6226a404d496fb1eba8650dbe15a7
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Enterovirus-induced infection of the central nervous system (CNS) results in acute inflammation of the brain (encephalitis) and constitutes a significant global burden to human health. These viruses are thought to be highly cytolytic, therefore norma
Externí odkaz:
https://doaj.org/article/354089ece8b64623b0805538392e8792
Autor:
Mei-Ling Li, Jing-Yi Lin, Bo-Shiun Chen, Kuo-Feng Weng, Shin-Ru Shih, Jesse Davila Calderon, Blanton S Tolbert, Gary Brewer
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221048 (2019)
Enterovirus 71 (EV71) induces apoptosis to promote viral particle release. Earlier work showed that EV71 utilizes its 3C protease to induce apoptosis in a caspase-3-dependent pathway, though the mechanism is unknown. However, work from Vagner, Holcik
Externí odkaz:
https://doaj.org/article/28d0401486314236bb1ca9c517ed92a7
Autor:
Bo Shiun Chen, Reta Birhanu Kitata, Chia-Feng Tsai, Wai-Kok Choong, Alexey I. Nesvizhskii, Yun Chien Chang, Ting-Yi Sung, Yu-Ju Chen, Pei-Yi Lin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
Phosphoproteomics can provide insights into cellular signaling dynamics. To achieve deep and robust quantitative phosphoproteomics profiling for minute amounts of sample, we here develop a global phosphoproteomics strategy based on data-independent a
Autor:
Avijit K. Adak, Kuan‐Ting Huang, Chien‐Yu Liao, Yuan‐Jung Lee, Wen‐Hua Kuo, Yi‐Ren Huo, Pei‐Jhen Li, Yi‐Ju Chen, Bo‐Shiun Chen, Yu‐Ju Chen, Kuo Chu Hwang, Wun‐Shang Wayne Chang, Chun‐Cheng Lin
Publikováno v:
Chemistry – A European Journal. 28
Autor:
Avijit K. Adak, Kuan‐Ting Huang, Chien‐Yu Liao, Yuan‐Jung Lee, Wen‐Hua Kuo, Yi‐Ren Huo, Pei‐Jhen Li, Yi‐Ju Chen, Bo‐Shiun Chen, Yu‐Ju Chen, Kuo Chu Hwang, Wun‐Shang Wayne Chang, Chun‐Cheng Lin
Publikováno v:
Chemistry – A European Journal. 28
The excellent molecular recognition capabilities of monoclonal antibodies (mAbs) have opened up exciting opportunities for biotherapeutic discovery. Taking advantage of the full potential of this tool necessitates affinity ligands capable of conjugat
Autor:
Bo-Shiun Chen, John A. Gray, Antonio Sanz-Clemente, Zhe Wei, Eleanor V. Thomas, Roger A. Nicoll, Katherine W. Roche
Publikováno v:
Cell Reports, Vol 2, Iss 5, Pp 1120-1128 (2012)
Membrane-associated guanylate kinases (MAGUKs) are the major family of scaffolding proteins at the postsynaptic density. The PSD-MAGUK subfamily, which includes PSD-95, PSD-93, SAP97, and SAP102, is well accepted to be primarily involved in the synap
Externí odkaz:
https://doaj.org/article/fb714d238a724fab8a66524b370c6ebe
Publikováno v:
Biochem Biophys Res Commun
The yeast ATP-dependent chromatin remodeling enzyme Fun30 has been shown to regulate heterochromatin silencing, DNA repair, transcription, and chromatin organization. Although chromatin structure has been proposed to influence splice site recognition
Publikováno v:
Molecular Neurobiology. 55:6215-6226
Synapse-associated protein 102 (SAP102) is a scaffolding protein highly expressed early in development and plays a critical role in mediating glutamate receptor trafficking during synaptogenesis. Mutations in human SAP102 have been reported to cause