Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Bo Ruem Yoon"'
Autor:
Yeon Jun Kang, Woorim Song, Su Jeong Lee, Seung Ah Choi, Sihyun Chae, Bo Ruem Yoon, Hee Young Kim, Jung Ho Lee, Chulwoo Kim, Joo-Youn Cho, Hyun Je Kim, Won-Woo Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 8, Pp 1776-1790 (2024)
Abstract Branched-chain amino acids (BCAAs), particularly leucine, are indispensable AAs for immune regulation through metabolic rewiring. However, the molecular mechanism underlying this phenomenon remains unclear. Our investigation revealed that T-
Externí odkaz:
https://doaj.org/article/b4e53a082b53482fac20f35f352142b7
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Monocytes are important cellular effectors of innate immune defense. Human monocytes are heterogeneous and can be classified into three distinct subsets based on CD14 and CD16 expression. The expansion of intermediate CD14+CD16+ monocytes has been re
Externí odkaz:
https://doaj.org/article/5701bbf7289146ba942007fd26c363bc
Autor:
Donghyun Kim, Ho Lee, Jaemoon Koh, Jae Sung Ko, Bo Ruem Yoon, Yoon Kyung Jeon, Young Min Cho, Tae Han Kim, Yun-Suhk Suh, Hyuk-Joon Lee, Han-Kwang Yang, Kyong Soo Park, Hye Young Kim, Chang Woo Lee, Won-Woo Lee, Doo Hyun Chung
Publikováno v:
Cell Reports, Vol 20, Iss 4, Pp 832-845 (2017)
IRF5 is a signature transcription factor that induces M1 macrophage polarization. However, little is known regarding cytosolic proteins that induce IRF5 activation for M1 polarization. Here, we report the interaction between ubiquitin E3 ligase Pelli
Externí odkaz:
https://doaj.org/article/1abcf8ef5aa6425fa64ea93f45c08b41
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Amino acids (AAs) are necessary nutrients which act not only as building blocks in protein synthesis but also in crucial anabolic cellular signaling pathways. It has been demonstrated that SLC7A5 is a critical transporter that mediates uptake of seve
Externí odkaz:
https://doaj.org/article/fb2d72364f45432589bf243035c612e9
Autor:
Bo Ruem Yoon, Su-Jin Yoo, Yeon ho Choi, Yeon-Ho Chung, Jinhyun Kim, In Seol Yoo, Seong Wook Kang, Won-Woo Lee
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109775 (2014)
Monocytes function as crucial innate effectors in the pathogenesis of chronic inflammatory diseases, including autoimmunity, as well as in the inflammatory response against infectious pathogens. Human monocytes are heterogeneous and can be classified
Externí odkaz:
https://doaj.org/article/66d43d9b49d141d097cf19d86e4e40be
Autor:
Bonah Kim, Hee Young Kim, Bo Ruem Yoon, Jina Yeo, Ji In Jung, Kyung-Sang Yu, Hyeon Chang Kim, Su-Jin Yoo, Jin Kyun Park, Seong Wook Kang, Won-Woo Lee
Publikováno v:
Science signaling. 15(716)
The essential micronutrient zinc regulates immune responses by affecting signaling pathways. In activated monocytes and macrophages, signaling networks mediate the metabolic reprogramming that meets the demands of participation in immune responses. H
Publikováno v:
Journal of Molecular Medicine. 97:369-383
Monosodium urate (MSU) crystals are an endogenous sterile particulate that has been identified as a potent damage-associated molecular pattern (DAMP). In humans, the induction of IL-1β production through MSU-induced NLRP3 inflammasome activation in
Autor:
Boyun Kim, S.W. Kang, Hojae Kim, Won Woo Lee, Hyae Young Kim, Jin Kyun Park, Yeo J, Kyung Sang Yu, Bo Ruem Yoon
The essential micronutrient zinc plays regulatory roles in immune responses through its ability to affect signaling pathways. In activated monocytes/macrophages, signaling networks mediate metabolic reprogramming in order to meet the demands of parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7ea983baed52a11409ef19bbb033461
https://doi.org/10.1101/2021.04.16.437150
https://doi.org/10.1101/2021.04.16.437150
Autor:
Ho Lee, Yun Suhk Suh, Han-Kwang Yang, Yoon Kyung Jeon, Hyuk Joon Lee, Hyeyoung Kim, Won Woo Lee, Donghyun Kim, Jae Sung Ko, Jaemoon Koh, Bo Ruem Yoon, Kyong Soo Park, Young Min Cho, Chang-Woo Lee, Doo Hyun Chung, Tae Han Kim
Publikováno v:
Cell Reports, Vol 20, Iss 4, Pp 832-845 (2017)
CELL REPORTS(20): 4
CELL REPORTS(20): 4
Summary IRF5 is a signature transcription factor that induces M1 macrophage polarization. However, little is known regarding cytosolic proteins that induce IRF5 activation for M1 polarization. Here, we report the interaction between ubiquitin E3 liga
Autor:
Sang Kyu Ye, Won Woo Lee, Seong Wook Kang, Eun Kyoung Kim, Sun Ho Kwon, Eun Hee Yi, Kum Hee Noh, Bo Ruem Yoon, Hyun Gyu Lee, Jung Sook Choi, In Chul Park, Byung Hak Kim
Publikováno v:
Biochemical Pharmacology. :47-57
Autoimmune rheumatoid arthritis is characterized by chronic inflammation and hyperplasia in the synovial joints. Although the cause of rheumatoid arthritis is largely unknown, substantial evidence has supported the importance of immune cells and infl