Zobrazeno 1 - 10
of 2 035
pro vyhledávání: '"Bo Qin"'
Autor:
Chris Chun-Yiu Chan, Qian Guo, Jasper Fuk-Woo Chan, Kaiming Tang, Jian-Piao Cai, Kenn Ka-Heng Chik, Yixin Huang, Mei Dai, Bo Qin, Chon Phin Ong, Allen Wing-Ho Chu, Wan-Mui Chan, Jonathan Daniel Ip, Lei Wen, Jessica Oi-Ling Tsang, Tong-Yun Wang, Yubin Xie, Zhenzhi Qin, Jianli Cao, Zi-Wei Ye, Hin Chu, Kelvin Kai-Wang To, Xing-Yi Ge, Tao Ni, Dong-Yan Jin, Sheng Cui, Kwok-Yung Yuen, Shuofeng Yuan
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4028-4044 (2024)
There are only eight approved small molecule antiviral drugs for treating COVID-19. Among them, four are nucleotide analogues (remdesivir, JT001, molnupiravir, and azvudine), while the other four are protease inhibitors (nirmatrelvir, ensitrelvir, le
Externí odkaz:
https://doaj.org/article/e580066405f243c6820a3a4400b16bcf
Autor:
Kaixiang Zhu, Lili Song, Linyue Wang, Lei Hua, Ziyu Luo, Tongyun Wang, Bo Qin, Shuofeng Yuan, Xiaopan Gao, Wenyi Mi, Sheng Cui
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4164-4173 (2024)
Viruses often manipulate ubiquitination pathways to facilitate their replication and pathogenesis. CUL2ZYG11B known as the substrate receptor of cullin-2 RING E3 ligase, is bound by SARS-CoV-2 ORF10 to increase its E3 ligase activity, leading to degr
Externí odkaz:
https://doaj.org/article/aff45cef243f48ada74712a089d7e713
Publikováno v:
npj Climate and Atmospheric Science, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract While deep learning models have shown promising capabilities in ENSO prediction, their inherent black-box nature often leads to a lack of physical consistency and interpretability. Here, we introduce ENSO-PhyNet, a Transformer-based model fo
Externí odkaz:
https://doaj.org/article/ae925d85997649dcaa8f4e8d0904dab9
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 9, Pp 1723-1730 (2024)
AIM: To assess the causal link between 211 gut microbiota (GM) taxa and dry age-related macular degeneration (dAMD) risk. METHODS: Mendelian randomization using instrumental factors taken from a genome-wide association study (GWAS) were used. Inverse
Externí odkaz:
https://doaj.org/article/a5a882661126428dbdbb67d0d87b490f
Autor:
Xiaopan Gao, Kaixiang Zhu, Lin Wang, Kun Shang, Lei Hua, Bo Qin, Hongtao Zhu, Wei Ding, Sheng Cui
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/bd31296a15ba4405b9ff9bc0a9de0520
Publikováno v:
Meitan xuebao, Vol 49, Iss S1, Pp 208-219 (2024)
Abrasive water jet is a highly efficient cutting technology. Through some sandstone cutting tests, the research on the optimal impact angle and inclined cutting mechanism of rock-like materials is carried out. Based on the macroscopic and microscopic
Externí odkaz:
https://doaj.org/article/bf640c08c34045678dbedf1b3caeed68
Autor:
Ekaterina Borisova, Andrew G. Newman, Marta Couce Iglesias, Rike Dannenberg, Theres Schaub, Bo Qin, Alexandra Rusanova, Marisa Brockmann, Janina Koch, Marieatou Daniels, Paul Turko, Olaf Jahn, David R. Kaplan, Marta Rosário, Takao Iwawaki, Christian M. T. Spahn, Christian Rosenmund, David Meierhofer, Matthew L. Kraushar, Victor Tarabykin, Mateusz C. Ambrozkiewicz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract The mammalian neocortex comprises an enormous diversity regarding cell types, morphology, and connectivity. In this work, we discover a post-transcriptional mechanism of gene expression regulation, protein translation, as a determinant of co
Externí odkaz:
https://doaj.org/article/66af00ce766642a5b9c7bd2aa0b9eb91
Autor:
Xiaopan Gao, Bei Wang, Kaixiang Zhu, Linyue Wang, Bo Qin, Kun Shang, Wei Ding, Jianwei Wang, Sheng Cui
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract SETD3 is an essential host factor for the replication of a variety of enteroviruses that specifically interacts with viral protease 2A. However, the interaction between SETD3 and the 2A protease has not been fully characterized. Here, we use
Externí odkaz:
https://doaj.org/article/89368cd55fec45e983e4b3040f4b46b3
Autor:
Angela R. Omilian, Rikki Cannioto, Lucas Mendicino, Leighton Stein, Wiam Bshara, Bo Qin, Elisa V. Bandera, Nur Zeinomar, Scott I. Abrams, Chi-Chen Hong, Song Yao, Thaer Khoury, Christine B. Ambrosone
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-12 (2024)
Abstract Background Tumor-associated macrophages (TAMs) are a prominent immune subpopulation in the tumor microenvironment that could potentially serve as therapeutic targets for breast cancer. Thus, it is important to characterize this cell populati
Externí odkaz:
https://doaj.org/article/6f527a7fa43b4abe837920ef9add5330
Autor:
Bo Qin, Shi-jie Fu, Xiong-fei Xu, Jiu-jie Yang, Yuping Wang, Lin-na Wang, Bai-xiong Huang, Jing Zhong, Wan-yu Wu, Heng-ao Lu, Betty Yuen Kwan Law, Nick Wang, Io Nam Wong, Vincent Kam Wai Wong
Publikováno v:
Pharmacological Research, Vol 208, Iss , Pp 107349- (2024)
In future regenerative medicine, far-infrared radiation (FIR) may be an essential component of optical therapy. Many studies have confirmed or validated the efficacy and safety of FIR in various diseases, benefiting from new insights into FIR mechani
Externí odkaz:
https://doaj.org/article/4eebceedf7174b5c9e20ffe6b7742dbc