Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Bo Olsson"'
Autor:
Ross L. Walenga, Clare Butler, Brent A. Craven, P. Worth Longest, Raja Mohamed, Bryan Newman, Bo Olsson, Günther Hochhaus, Bing V. Li, Markham C. Luke, Liang Zhao, Andrzej Przekwas, Robert Lionberger
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 5, Pp 560-574 (2023)
Abstract In silico mechanistic modeling approaches have been designed by various stakeholders with the goal of supporting development and approval of generic orally inhaled drug products in the United States. This review summarizes the presentations
Externí odkaz:
https://doaj.org/article/5c0bae85a62f4563a75d8c48d83d86ce
Autor:
Ross L. Walenga, Clare Butler, Brent A. Craven, P. Worth Longest, Raja Mohamed, Bryan Newman, Bo Olsson, Günther Hochhaus, Bing V. Li, Markham C. Luke, Liang Zhao, Andrzej Przekwas, Robert Lionberger
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. 12:560-574
In silico mechanistic modeling approaches have been designed by various stakeholders with the goal of supporting development and approval of generic orally inhaled drug products in the United States. This review summarizes the presentations and panel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e424b5c22c189ca33b6ad5f4220ebe03
https://doi.org/10.1002/psp4.12889
https://doi.org/10.1002/psp4.12889
Autor:
Sandra Anderson, Paul Atkins, Per Bäckman, David Cipolla, Andrew Clark, Evangelia Daviskas, Bernd Disse, Plamena Entcheva-Dimitrov, Rick Fuller, Igor Gonda, Hans Lundbäck, Bo Olsson, Jeffry Weers
Publikováno v:
Pharmacological Reviews. 74:48-118
The purpose of this review is to summarize essential pharmacological, pharmaceutical, and clinical aspects in the field of orally inhaled therapies that may help scientists seeking to develop new products. After general comments on the rationale for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbde82f7cedbd8214632aa4a27cd4580
https://doi.org/10.1124/pharmrev.120.000108
https://doi.org/10.1124/pharmrev.120.000108
Autor:
Stavros C. Kassinos, Bo Olsson
Publikováno v:
Journal of Aerosol Medicine and Pulmonary Drug Delivery. 34:115-123
Background: Mechanistic computer models for calculation of total and regional deposition of aerosols in the lungs are important tools for predicting or understanding clinical studies and for facili...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5735de7d646534a1912b880c8492e4
https://doi.org/10.1089/jamp.2020.1620
https://doi.org/10.1089/jamp.2020.1620
Autor:
Elham Amini, Per Bäckman, Erica Bäckström, Martyn Biddiscombe, Britta Bonn, Jens Markus Borghardt, Joy Conway, Anne Haaije de Boer, Martin Donnelley, Zachary Enlo-Scott, Ben Forbes, Markus Fridén, Mark Gardner, Anthony J. Hickey, Anneke Himstedt, Guenther Hochhaus, Eric A. Hoffman, Stavros Kassinos, Pantelis Koullapis, Ching-Long Lin, Hans Lundbäck, Kaye Morgan, Bo Olsson, David Parsons, Matthew Perry, Fotos Stylianou, Mårten Svensson, Magda Swedrowska, Josué Sznitman, Kyrre Thalberg, Omar Usmani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3f38ff3881f729112d0edfae6949002
https://doi.org/10.1016/b978-0-12-814974-4.00023-7
https://doi.org/10.1016/b978-0-12-814974-4.00023-7
In vitro methods to study dose deposition of inhaled medication can provide clinically relevant information about inhaler and nebulizer performance if conducted under patient realistic conditions, i.e., using realistic flow profiles, mouth-throat mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67b73ab9ef91369ae72871080b5c1402
https://doi.org/10.1016/b978-0-12-814974-4.00010-9
https://doi.org/10.1016/b978-0-12-814974-4.00010-9
Publikováno v:
Journal of Aerosol Medicine and Pulmonary Drug Delivery. 30:108-117
Exposure following oral inhalation depends on the deposition pattern of the inhaled aerosol, the extent and rate of oral and pulmonary absorption, as well as systemic distribution and clearance. For lipophilic inhaled compounds with low water solubil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2adbb7bc188bf9a971e5bdf84c0491
https://doi.org/10.1089/jamp.2016.1306
https://doi.org/10.1089/jamp.2016.1306
Autor:
Johanna Melin, Adriaan Cleton, Susanne Prothon, Ulrika Wählby Hamrén, Per Bäckman, Carl Amilon, Bo Olsson, Charlotte Kloft, Carin Jorup
Publikováno v:
The AAPS Journal. 19:865-874
AZD5423 is a non-steroidal glucocorticoid receptor modulator, with low aqueous solubility, developed for treatment of asthma and COPD. In this work, we aim to evaluate and compare the absorption pharmacokinetics (PK) of AZD5423 after inhalation via f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bef2a673b15ab55bbe7e9df92558fe65
https://doi.org/10.1208/s12248-016-0042-8
https://doi.org/10.1208/s12248-016-0042-8
Autor:
Bo Olsson, Sylvia Kirchengast
Publikováno v:
Anthropologischer Anzeiger. 73:323-333
SUMMARY The aim of this pilot study is to test a new approach to handedness assessment based on the concept of the leading hand. A well-established graphomotor performance test of handedness (H-D-T) and a new test according on the concept of the lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563e9e13aebcc63ef618055d9d327533
https://doi.org/10.1127/anthranz/2016/0650
https://doi.org/10.1127/anthranz/2016/0650
Publikováno v:
Journal of Aerosol Science. 144:105541
In silico methods can be used to estimate regional deposition of inhaled aerosols in regions of the lung that are inaccessible by direct measurements. Knowledge of deposited dose is important for assessing the efficacy of inhaled pharmaceutical aeros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50c3c4a28cf54acf59e7cadbf8e871da
https://doi.org/10.1016/j.jaerosci.2020.105541
https://doi.org/10.1016/j.jaerosci.2020.105541