Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Bo O. Zhou"'
Autor:
Danting Zhang, Weimin Lin, Shuang Jiang, Peng Deng, Linfeng Liu, Qian Wang, Rui Sheng, Hui Sophie Shu, Lijun Wang, Weiguo Zou, Bo O. Zhou, Junjun Jing, Ling Ye, Bo Yu, Shiwen Zhang, Quan Yuan
Publikováno v:
Advanced Science, Vol 10, Iss 29, Pp n/a-n/a (2023)
Abstract Periodontium supports teeth in a mechanically stimulated tissue environment, where heterogenous stem/progenitor populations contribute to periodontal homeostasis. In this study, Leptin receptor+ (Lepr+) cells are identified as a distinct per
Externí odkaz:
https://doaj.org/article/6131c88eb9774848905c6fd58fd21d68
Autor:
Bo Gao, Jinhua Yin, Xiaolong Xu, Jing Fan, Di Wang, Chao Zheng, Weiguang Lu, Pengzhen Cheng, Jicheng Sun, Dong Wang, Lu Li, Bo O. Zhou, Liu Yang, Zhuojing Luo
Publikováno v:
Journal of Orthopaedic Translation, Vol 21, Iss , Pp 91-99 (2020)
Background/objective: Intervertebral disc degeneration (IDD) remains to be an intractable clinical challenge. Although IDD is characterised by loss of notochordal cells (NCs) and dysfunction of nucleus pulposus (NP) cells, little is known about the o
Externí odkaz:
https://doaj.org/article/1852c35275c5472398f829aab528e2ee
Publikováno v:
Development. 150
Several cell types have been proposed to create the required microenvironment for spermatogenesis. However, expression patterns of the key growth factors produced by these somatic cells have not been systematically studied and no such factor has been
Autor:
Jianfang Wang, Qiaoling Zhu, Dandan Cao, Qiqi Peng, Xiaoying Zhang, Chong Li, Chen Zhang, Bo O. Zhou, Rui Yue
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 120(1)
Insulin-like growth factor I (IGF-1) is a key regulator of tissue growth and development in response to growth hormone stimulation. In the skeletal system, IGF-1 derived from osteoblasts and chondrocytes are essential for normal bone development; how
Autor:
Jiaying Xie, Mengyao Sheng, Shaoqin Rong, Chao Wang, Wanling Wu, Jingru Huang, Yue Sun, Pingyue Chen, Yushuang Wu, Yuanxian Wang, Lan Wang, Bo O. Zhou, Xinxin Huang, Colum P. Walsh, Stefan K. Bohlander, Jian Huang, Xiaoqin Wang, Hai Gao, Dan Zhou, Yuheng Shi, Guo-Liang Xu
Somatic loss-of-function mutations of the dioxygenase Ten-eleven translocation-2 (TET2) occur frequently in individuals with clonal hematopoiesis (CH) and acute myeloid leukemia (AML). These common hematopoietic disorders can be recapitulated in mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33358141db9d0ac9f6929bd95408d7e4
https://doi.org/10.1101/2022.12.17.520899
https://doi.org/10.1101/2022.12.17.520899
Autor:
Bo O. Zhou, Xinyu Thomas Tang, Jia Yuan, Xiujuan Yin, Minghui Lin, Yi Jacky Peng, Zhenggang Ren, Gaoxiang Ge, Shanshan Wang, GuoGuo Shang
Publikováno v:
Hepatology. 74:1578-1594
Background and aims Studies of the identity and pathophysiology of fibrogenic HSCs have been hampered by a lack of genetic tools that permit specific and inducible fate-mapping of these cells in vivo. Here, by single-cell RNA sequencing of nonparench
Autor:
Sang-Uk Seo, Yeji Kim, Bo O. Zhou, Kwang Soon Kim, Su-Hyun Lee, Yong-Soo Lee, O. Eunju, Tae-Young Kim, Seung Il Kim, Mi-Na Kweon
Publikováno v:
Experimental & Molecular Medicine
Although functional interplay between intestinal microbiota and distant sites beyond the gut has been identified, the influence of microbiota-derived metabolites on hematopoietic stem cells (HSCs) remains unclear. This study investigated the role of
Autor:
Jin-Qiu Zhou, Fei-Long Meng, Pengfei Dai, Can Hu, Bo O. Zhou, Ming-Hong He, Qianjin Li, Jia-Cheng Liu
Publikováno v:
Nucleic Acids Research
Telomeres at the ends of eukaryotic chromosomes are essential for genome integrality and stability. In order to identify genes that sustain telomere maintenance independently of telomerase recruitment, we have exploited the phenotype of over-long tel
Autor:
Guangdun Peng, Yujie Chen, Naihe Jing, Wenjie Dong, Xiujuan Yin, Xinyu Thomas Tang, Bo O. Zhou, Di Demi He, Guizhong Cui
Publikováno v:
Stem Cell Reports
Summary Hematopoietic stem cells (HSCs) and skeletal stem cells (SSCs) cohabit in the bone marrow. KITL (C-KIT ligand) from LEPR+ adult bone marrow stromal cells is pivotal for HSC maintenance. In contrast, it remains unclear whether KITL/C-KIT signa
Autor:
Junchao Dong, Rafael Casellas, Qiu Wu, Xiaoqi Zheng, Wubing Zhang, Pengfei Dai, Tengfei Xiao, Xiaojing Liu, Dingpeng Yang, Jiazhi Hu, Shan Zha, Brian J. Lee, X. Shirley Liu, Min Huang, Leng-Siew Yeap, Tingting Liu, Bo O. Zhou, Yafang Shang, Liu Daisy Liu, Fei-Long Meng
Publikováno v:
Cell Research
Programmed DNA recombination in mammalian cells occurs predominantly in a directional manner. While random DNA breaks are typically repaired both by deletion and by inversion at approximately equal proportions, V(D)J and class switch recombination (C