Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Bo Nordenskjöld"'
Autor:
Helena Fohlin, Anna Nordenskjöld, Johan Rosell, Mårten Fernö, Tommy Fornander, Lisa Rydén, Lambert Skoog, Bo Nordenskjöld, Olle Stål
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background: Hormone receptor positivity predicts benefit from endocrine therapy but the knowledge about the long-term survival of patients with different tumor receptor levels is limited. In this study, we describe the 25 years outcome of tamoxifen (
Externí odkaz:
https://doaj.org/article/70fb0a9414d446158f65dbae4436b48e
Autor:
Terese Engström, Maria Ekholm, Mårten Fernö, Christine Lundgren, Bo Nordenskjöld, Olle Stål, Pär-Ola Bendahl, Julia Tutzauer, Lisa Rydén
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
ABSTRACT Background and purpose: Tamoxifen remains an important adjuvant treatment in premenopausal patients with hormone receptor-positive breast cancer. Thus, determination of hormone receptors is important. Here, we compare cytosol-based methods,
Externí odkaz:
https://doaj.org/article/3af36158a1dc4d0f99ce91c65e6aa575
Autor:
Anna Nordenskjöld, Helena Fohlin, Johan Rosell, Nils-Olof Bengtsson, Tommy Fornander, Thomas Hatschek, Henrik Lindman, Per Malmström, Lisa Rydén, Arne Wallgren, Olle Stål, Bo Nordenskjöld
Publikováno v:
Breast, Vol 71, Iss , Pp 63-68 (2023)
Background: Tamoxifen is an established treatment for breast cancer, but its long-term effects on survival and on secondary cancers are not fully evaluated. Material and methods: We studied 30 years outcome of 4124 postmenopausal patients who were ra
Externí odkaz:
https://doaj.org/article/487528a90ae34cc4bee6e74d37bc5e34
Autor:
Christine Lundgren, Julia Tutzauer, Sarah E. Church, Olle Stål, Maria Ekholm, Carina Forsare, Bo Nordenskjöld, Mårten Fernö, Pär-Ola Bendahl, Lisa Rydén
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-20 (2023)
Abstract Background Gene expression (GEX) signatures in breast cancer provide prognostic information, but little is known about their predictive value for tamoxifen treatment. We examined the tamoxifen-predictive value and prognostic effects of diffe
Externí odkaz:
https://doaj.org/article/f09fa8d43985469ab9231f4bffcde4a9
Autor:
Christine Lundgren, Pär-Ola Bendahl, Sarah E. Church, Maria Ekholm, Mårten Fernö, Carina Forsare, Ute Krüger, Bo Nordenskjöld, Olle Stål, Lisa Rydén
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract PAM50 intrinsic subtyping and risk of recurrence (ROR) score are approved for risk profiling in postmenopausal women. We aimed to examine their long-term prognostic value in terms of breast cancer-free interval (BCFi) and overall survival (O
Externí odkaz:
https://doaj.org/article/6ac42a655e1c44b8aaf372ca6538233d
Autor:
Sanne Løkkegaard, Daniel Elias, Carla L. Alves, Martin V. Bennetzen, Anne-Vibeke Lænkholm, Martin Bak, Morten F. Gjerstorff, Lene E. Johansen, Henriette Vever, Christina Bjerre, Tove Kirkegaard, Bo Nordenskjöld, Tommy Fornander, Olle Stål, Linda S. Lindström, Laura J. Esserman, Anne E. Lykkesfeldt, Jens S. Andersen, Rikke Leth-Larsen, Henrik J. Ditzel
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-15 (2021)
Abstract Resistance to endocrine therapy in estrogen receptor-positive (ER+) breast cancer is a major clinical problem with poorly understood mechanisms. There is an unmet need for prognostic and predictive biomarkers to allow appropriate therapeutic
Externí odkaz:
https://doaj.org/article/c7b5ad6a5a674cfcb8ece9f12b5c68d6
Autor:
Christine Lundgren, Pär-Ola Bendahl, Maria Ekholm, Mårten Fernö, Carina Forsare, Ute Krüger, Bo Nordenskjöld, Olle Stål, Lisa Rydén
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-14 (2020)
Abstract Background Tumour-infiltrating lymphocytes (TILs) are of important prognostic and predictive value in human epidermal growth factor receptor 2-positive (HER2+) breast cancer (BC) and triple-negative breast cancer (TNBC), but their clinical r
Externí odkaz:
https://doaj.org/article/197a7ddeb1714ec8aafbbb51dc62b994
Autor:
Tove Sivik, Cecilia Gunnarsson, Tommy Fornander, Bo Nordenskjöld, Lambert Skoog, Olle Stål, Agneta Jansson
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40568 (2012)
INTRODUCTION: 17β-Hydroxysteroid dehydrogenases (17βHSDs) are important enzymes regulating the pool of bioactive steroids in the breast. The current study was undertaken in order to evaluate implications of 17βHSD14 in breast cancer, measuring 17
Externí odkaz:
https://doaj.org/article/a0a13b67e2044dd9b23c720ee7600f66
Autor:
Annelie, Johansson, Huma, Dar, Laura J, van 't Veer, Nicholas P, Tobin, Gizeh, Perez-Tenorio, Anna, Nordenskjöld, Ulla, Johansson, Johan, Hartman, Lambert, Skoog, Christina, Yau, Christopher C, Benz, Laura J, Esserman, Olle, Stål, Bo, Nordenskjöld, Tommy, Fornander, Linda S, Lindström
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40(35)
To assess the long-term (20-year) endocrine therapy benefit in premenopausal patients with breast cancer.Secondary analysis of the Stockholm trial (STO-5, 1990-1997) randomly assigning 924 premenopausal patients to 2 years of goserelin (3.6 mg subcut
Autor:
Oscar Danielsson, Huma Dar, Gizeh Perez-Tenorio, Anna Nordenskjöld, Christina Yau, Christopher C. Benz, Laura J. Esserman, Bo Nordenskjöld, Olle Stål, Tommy Fornander, Annelie Johansson, Linda S. Lindström
Publikováno v:
Cancer Research. 83:P3-05
Background: Women with estrogen receptor (ER)-positive disease have a long-term risk of distant recurrence. The poor survival of premenopausal women diagnosed with breast cancer combined with the otherwise long life expectancy makes it especially imp