Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Bo L. Chawes"'
Autor:
Nicole Prince, Rachel S. Kelly, Su H. Chu, Priyadarshini Kachroo, Yulu Chen, Kevin M. Mendez, Sofina Begum, Hans Bisgaard, Klaus Bønnelykke, Min Kim, Ofer Levy, Augusto A. Litonjua, Craig E. Wheelock, Scott T. Weiss, Bo L. Chawes, Jessica A. Lasky-Su
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Respiratory infections are a leading cause of morbidity and mortality in early life, and recurrent infections increase the risk of developing chronic diseases. The maternal environment during pregnancy can impact offspring health, but the fa
Externí odkaz:
https://doaj.org/article/ad6dafe46ea84769bc12cbb3f2c1820a
Autor:
Mie Sylow Liljendahl, Astrid Sevelsted, Bo L. Chawes, Jakob Stokholm, Klaus Bønnelykke, Zorana Jovanovic Andersen, Hans Bisgaard
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Asthma and autoimmune disorders might be affected by opposing immune mechanisms, T helper cells type 2 (Th2) and T helper cells type 1 (Th1) immunity, respectively. Knowledge on comorbidity can increase understanding of the underlying etiolo
Externí odkaz:
https://doaj.org/article/d938fcc9b208498c9a57e1a4e4ee3a7b
Autor:
Emil Dalgaard Christensen, Mathis Hjort Hjelmsø, Jonathan Thorsen, Shiraz Shah, Tamsin Redgwell, Christina Egeø Poulsen, Urvish Trivedi, Jakob Russel, Shashank Gupta, Bo L. Chawes, Klaus Bønnelykke, Søren Johannes Sørensen, Morten Arendt Rasmussen, Hans Bisgaard, Jakob Stokholm
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Background Growing up with siblings has been linked to numerous health outcomes and is also an important determinant for the developing microbiota. Nonetheless, research into the role of having siblings on the developing microbiota has mainl
Externí odkaz:
https://doaj.org/article/347ae95770244240bc9cdf8161f74756
Autor:
Daniel P. Henriksen, Uffe Bodtger, Kirsten Sidenius, Niels Maltbaek, Lars Pedersen, Hanne Madsen, Ehm A. Andersson, Ole Norgaard, Louise K. Madsen, Bo L. Chawes
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 16, Iss 1, Pp 1-12 (2020)
Abstract Background Omalizumab is approved for treating severe allergic asthma from age 6, but the definition of severe asthma including a systematic assessment to rule out difficult-to-treat asthma has changed since the drug was approved in 2003. Me
Externí odkaz:
https://doaj.org/article/dad67435d1f64bf09391deb0f44ce995
Autor:
Nicklas Brustad, Bo L. Chawes, Jonathan Thorsen, Martin Krakauer, Jessica Lasky-Su, Scott T. Weiss, Jakob Stokholm, Klaus Bønnelykke, Hans Bisgaard
Publikováno v:
EClinicalMedicine, Vol 43, Iss , Pp 101254- (2022)
Summary: Background: Exposure to vitamin D in early life has been associated with improved bone mineralization, but no studies have investigated the combined effect of pregnancy supplementation and childhood 25(OH)D concentrations on bone health. Met
Externí odkaz:
https://doaj.org/article/9aaf939264514977baa5a870c30c944b
Autor:
Jonathan Thorsen, Morten A. Rasmussen, Johannes Waage, Martin Mortensen, Asker Brejnrod, Klaus Bønnelykke, Bo L. Chawes, Susanne Brix, Søren J. Sørensen, Jakob Stokholm, Hans Bisgaard
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Here, Thorsen et al. examine the microbiota during the first three months of life in a cohort of 700 children and find that microbial diversity and the relative abundances of Veillonella and Prevotella in the airways at one month of age are associate
Externí odkaz:
https://doaj.org/article/f2c87a49cb2d4d4da4089fc5b45bcc64
Autor:
Nicole Prince, Min Kim, Rachel S. Kelly, Joann Diray-Arce, Klaus Bønnelykke, Bo L. Chawes, Mengna Huang, Ofer Levy, Augusto A. Litonjua, Jakob Stokholm, Craig E. Wheelock, Hans Bisgaard, Scott T. Weiss, Jessica A. Lasky-Su
Publikováno v:
Metabolites, Vol 12, Iss 11, p 1108 (2022)
Recurrent respiratory infections are a leading cause of morbidity and mortality in early life, but there is no broadly accepted means to identify infection-prone children during this highly vulnerable period. In this study, we investigated associatio
Externí odkaz:
https://doaj.org/article/b0a58c3b89014f059bf82f4b27a21c7d
Autor:
Katrine Prætorius, Daniel P. Henriksen, Johannes M. Schmid, Pernille Printzlau, Lars Pedersen, Hanne Madsen, Ehm A. Andersson, Louise Klokker Madsen, Bo L. Chawes
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Externí odkaz:
https://doaj.org/article/8d795614a6424e4c8398094aead239e9
Autor:
Daniela Rago, Morten A. Rasmussen, Kathleen A. Lee-Sarwar, Scott T. Weiss, Jessica Lasky-Su, Jakob Stokholm, Klaus Bønnelykke, Bo L. Chawes, Hans Bisgaard
Publikováno v:
EBioMedicine, Vol 46, Iss , Pp 399-410 (2019)
Background: We recently demonstrated that maternal dietary supplementation with fish oil-derived n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFAs) during pregnancy reduces the risk of asthma in the offspring but the mechanisms involved are unk
Externí odkaz:
https://doaj.org/article/90fca1de542d41698bf60e2aceca2cf8
Autor:
Ni Wang, Ann-Marie M. Schoos, Jeppe M. Larsen, Susanne Brix, Anna H. Thysen, Morten A. Rasmussen, Jakob Stokholm, Klaus Bønnelykke, Hans Bisgaard, Bo L. Chawes
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 587-593 (2019)
Background: Autoimmunity and allergy have been associated with decreased number and function of regulatory T-cells (Tregs) and low interleukin-2 (IL-2) levels. We aimed to investigate if the release of IL-2 from peripheral blood mononuclear cells (PB
Externí odkaz:
https://doaj.org/article/4442bf7918124418b450dd59463b80da