Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bo K, Sun"'
Autor:
Bo K. Sun, Jae J. Song, Jina Kim, Hyo R. Yoon, Joo Hang Kim, So Y. Kim, Dongxu Kang, Sujin Kang
Publikováno v:
Cellular Signalling. 24:1444-1452
The combination of curcumin and TRAIL and their role in enhancing apoptotic cell death has been reported by many studies. However, the exact molecular mechanism of apoptosis mediated by curcumin and tumor necrosis factor-related apoptosis-inducing li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3fe465672ea78c8af6f3babfd4e86f7
https://doi.org/10.1016/j.cellsig.2012.03.009
https://doi.org/10.1016/j.cellsig.2012.03.009
Publikováno v:
Cellular signalling. 25(1)
Previously, we showed that mitogen-activated protein kinase/extracellular signal-related kinase 4 (MEKK4) is responsible for p38 activation and that its activation during tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) treatment also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f836233be6407926a85aa7036c66f1
https://pubmed.ncbi.nlm.nih.gov/23085457
https://pubmed.ncbi.nlm.nih.gov/23085457
Autor:
So Y. Kim, Bo K. Sun, Sujin Choi, Jae J. Song, Hoan N. Nguyen, Hye Jin Choi, Seeun Oh, Yong J. Lee, Joo Hang Kim
The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been shown to activate mitogen-activated protein kinases (MAPKs) depending on caspase and mammalian sterile 20-like kinase 1 activations. However, the upstream molecule of MAPKs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c65566c90effa191f4b761bc0419ee
https://europepmc.org/articles/PMC3041593/
https://europepmc.org/articles/PMC3041593/
Publikováno v:
International journal of oncology. 38(1)
We previously observed that TRAIL induces acquired TRAIL resistance coinciding with increased Akt phosphorylation brought about by the Src-PI3K-Akt signaling pathways and mediated by c-Cbl. c-Cbl, a ubiquitously expressed cytoplasmic adaptor protein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e5acb7a9bf085f105933dd3e97ae87b
https://pubmed.ncbi.nlm.nih.gov/21109947
https://pubmed.ncbi.nlm.nih.gov/21109947
We have previously observed that TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) induces acquired TRAIL resistance by increasing Akt phosphorylation and Bcl-xL expression. In this study, we report that Src, c-Cbl, and PI3K are involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a051ad1b1f43151b19b67b005d5126
https://europepmc.org/articles/PMC2965849/
https://europepmc.org/articles/PMC2965849/
Autor:
Bo K. Sun, Hyo R. Yoon, Joo Hang Kim, Jae J. Song, Jina Kim, Sujin Kang, Dongxu Kang, So Y. Kim
Publikováno v:
Cellular Signalling. 24:2407
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae6034acd7107e8f8f3d266a4c6536d7
https://doi.org/10.1016/j.cellsig.2012.08.013
https://doi.org/10.1016/j.cellsig.2012.08.013
Publikováno v:
Cancer Research. 71:4104-4104
Previously, we demonstrated that TRAIL-induced p38 activation was responsible for the increases of Akt catalytic and invasive activity. Interestingly, TRAIL induced dramatically Akt catalytic activation in TRAIL-sensitive cells, whereas TRAIL did not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::052ecdc71cc8fdd8eed85701a1feec0c
https://doi.org/10.1158/1538-7445.am2011-4104
https://doi.org/10.1158/1538-7445.am2011-4104
Autor:
Jae J. Song, Joo Hang Kim, So Y. Kim, Hoan N. Nguyen, Hyo R. Yoon, Seeun Oh, Bo K. Sun, Hye Jin Choi
Publikováno v:
Cancer Research. 71:4107-4107
The effect of combination of TRAIL and curcumin enhanced apoptotic cell death in many other studies. However, the exact molecular mechanism of enhanced apoptotic cell death by TRAIL plus curcumin was not yet completely understood. In this study, we c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e490c2c998fa4100b5bce2ab839ed26d
https://doi.org/10.1158/1538-7445.am2011-4107
https://doi.org/10.1158/1538-7445.am2011-4107
Autor:
Yong J. Lee, Joo Hang Kim, Hye Jin Choi, Bo K. Sun, So Y. Kim, Joohyuk Sohn, Seeun Oh, Jae J. Song
Publikováno v:
Cancer Research. 70:1276-1276
In this paper, we demonstrate that TRAIL-induced p38 activation is responsible for the increases of Akt catalytic activity and invasive activity. For the confirmation of increases of Akt catalytic and invasive activity induced by TRAIL-induced p38 ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1109f14619efdbf2936dfd46bf396a1
https://doi.org/10.1158/1538-7445.am10-1276
https://doi.org/10.1158/1538-7445.am10-1276
Publikováno v:
Cancer Research. 70:1277-1277
In this paper, we demonstrate that TRAIL death receptors (DR4, DR5) have their own distinctive function during TRAIL treatment. For the examination of each receptor's role, FACS analysis, biotin labeling to plasma membrane and siRNA technique were us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::080fd327cdcff06bd8b05eacf3d64561
https://doi.org/10.1158/1538-7445.am10-1277
https://doi.org/10.1158/1538-7445.am10-1277