Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Bo Eun Heo"'
Autor:
Thanh Quang Nguyen, Bo Eun Heo, Seunghyeon Jeon, Anwesha Ash, Heehyun Lee, Cheol Moon, Jichan Jang
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Mycobacterium abscessus, a leading cause of severe lung infections in immunocompromised individuals, poses significant challenges for current therapeutic strategies due to resistance mechanisms. Therefore, understanding the intrinsic and acquired ant
Externí odkaz:
https://doaj.org/article/93886ba5dc984e319b4d587bdff95edd
Autor:
Thanh Quang Nguyen, Bo Eun Heo, Yujin Park, Seunghyeon Jeon, Arunima Choudhary, Cheol Moon, Jichan Jang
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT There is an unmet medical need for effective treatments against Mycobacterium abscessus infections. Although advanced molecular genetic tools to validate drug targets and resistance of M. abscessus exist, the practical design and constructio
Externí odkaz:
https://doaj.org/article/f71c57ac71f948f7993a270537292da2
Autor:
Thanh-Hau Huynh, Eun Seo Bae, Bo Eun Heo, Jayho Lee, Joon Soo An, Yun Kwon, Sang-Jip Nam, Ki-Bong Oh, Jichan Jang, Sang Kook Lee, Dong-Chan Oh
Publikováno v:
Marine Drugs, Vol 21, Iss 9, p 500 (2023)
Two new proton-deficient metabolites, tandocyclinones A and B (1 and 2), were discovered via the chemical profiling of the Streptomyces sp. strain TDH03, which was isolated from a marine sediment sample collected from the intertidal mudflat in Tando
Externí odkaz:
https://doaj.org/article/d26beefa22e44ad6bbff47f897353ea8
Autor:
Bui Thi Bich Hanh, Nguyen Thanh Quang, Yujin Park, Bo Eun Heo, Seunghyeon Jeon, June-Woo Park, Jichan Jang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Mycobacterium abscessus is a difficult respiratory pathogen to treat, when compared to other nontuberculus mycobacteria (NTM), due to its drug resistance. In this study, we aimed to find a new clarithromycin partner that potentiated strong, positive,
Externí odkaz:
https://doaj.org/article/7979a880a4a3424fbf25a7a472cb79ff
Autor:
Thanh Quang Nguyen, Bo Eun Heo, Bui Thi Bich Hanh, Seunghyeon Jeon, Yujin Park, Arunima Choudhary, Sujin Lee, Tae Ho Kim, Cheol Moon, Sun-Joon Min, Jichan Jang
Publikováno v:
Antimicrobial Agents and Chemotherapy.
Benzoxaboroles are a new class of leucyl-tRNA synthetase inhibitors. Epetraborole, a benzoxaborole, is a clinical candidate developed for Gram-negative infections and has been confirmed to exhibit favorable activity against a well known pulmonary pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79c686765735e240ec444b74efce9a82
https://doi.org/10.1128/aac.01567-22
https://doi.org/10.1128/aac.01567-22
Autor:
Thanh Quang Nguyen, Bui Thi Bich Hanh, Seunghyeon Jeon, Bo Eun Heo, Yujin Park, Arunima Choudhary, Cheol Moon, Jichan Jang
Publikováno v:
Antimicrob Agents Chemother
Q203 is a first-in-class drug candidate against Mycobacterium tuberculosis. In its recently completed phase 2 clinical trial, Q203 reduced the number of live M. tuberculosis cells in a dose-dependent manner. This orally active small molecule blocks M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75580b67136a8f4dab980e5bdd8b0c9f
https://pubmed.ncbi.nlm.nih.gov/36321819
https://pubmed.ncbi.nlm.nih.gov/36321819