Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Bo Akerström"'
Autor:
Amanda Kristiansson, Oskar Vilhelmsson Timmermand, Mohamed Altai, Sven-Erik Strand, Bo Åkerström, Anders Örbom
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Radioligand therapy with [177Lu]Lu-PSMA-617 can be used to prolong life and reduce tumor burden in terminally ill castration resistant prostate cancer patients. Still, accumulation in healthy tissue limits the activity that can be administer
Externí odkaz:
https://doaj.org/article/743ee4805dbe487dab38904bb8673f13
Autor:
Nishte Rassol, Charlotte Andersson, Daniella Pettersson, Amin Al-Awar, Emman Shubbar, Anikó Kovács, Bo Åkerström, Magnus Gram, Khalil Helou, Eva Forssell-Aronsson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Recombinant α1-microglobulin (A1M) is a proposed radioprotector during 177Lu-octreotate therapy of neuroendocrine tumors (NETs). To ensure a maintained therapeutic effect, we previously demonstrated that A1M does not affect the 177Lu-octreo
Externí odkaz:
https://doaj.org/article/d08f21ecdcde4e42a86b298d4798120c
Autor:
Abdul Ghani Alattar, Amanda Kristiansson, Helena Karlsson, Suvi Vallius, Jonas Ahlstedt, Eva Forssell-Aronsson, Bo Åkerström, Sven-Erik Strand, Johan Flygare, Magnus Gram
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 928 (2023)
177Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) is used clinically to treat metastasized or unresectable neuroendocrine tumors (NETs). Although 177Lu-DOTATATE is mostly well tolerated in patients, bone marrow suppression and long-term ren
Externí odkaz:
https://doaj.org/article/75f059fe93d84de5ae531b78fc83fa73
Autor:
Amanda Kristiansson, Oskar Vilhelmsson Timmermand, Mohamed Altai, Joanna Strand, Sven-Erik Strand, Bo Åkerström, Anders Örbom
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 731 (2022)
Prostate cancer (PC) is one of the most common malignancies affecting men, with poor prognosis after progression to metastatic castration-resistant prostate cancer (mCRPC). Radioligand therapy (RLT) targeting the overexpressed PSMA on PC cells, with,
Externí odkaz:
https://doaj.org/article/d95b91a77fca44f88b04e2e19afd0d10
Autor:
Lina Youssef, Lena Erlandsson, Bo Åkerström, Jezid Miranda, Cristina Paules, Francesca Crovetto, Fatima Crispi, Eduard Gratacos, Stefan R. Hansson, Frank T. Spradley
Publikováno v:
PLoS ONE, Vol 15, Iss 9 (2020)
Hemopexin and α1-microglobulin act as scavengers to eliminate free heme-groups responsible for hemoglobin-induced oxidative stress. The present study evaluated maternal and fetal plasma concentrations of these scavengers in the different phenotypes
Externí odkaz:
https://doaj.org/article/812ed5d0e33141289e92785a211cff7b
Autor:
Lena Wester-Rosenlöf, Vera Casslén, Josefin Axelsson, Anneli Edström-Hägerwall, Magnus Gram, Madlene Holmqvist, Martin E Johansson, Iréne Larsson, David Ley, Karel Marsal, Matthias Mörgelin, Bengt Rippe, Sigurbjörg Rutardottir, Behnaz Shohani, Bo Akerström, Stefan R Hansson
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86353 (2014)
Preeclampsia (PE) is a serious pregnancy complication that manifests as hypertension and proteinuria after the 20(th) gestation week. Previously, fetal hemoglobin (HbF) has been identified as a plausible causative factor. Cell-free Hb and its degrada
Externí odkaz:
https://doaj.org/article/575d93588e484fe7853e0852d1f5ae27
Autor:
Magnus G Olsson, Maria Allhorn, Jörgen Larsson, Martin Cederlund, Katarina Lundqvist, Artur Schmidtchen, Ole E Sørensen, Matthias Mörgelin, Bo Akerström
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27505 (2011)
During bleeding the skin is subjected to oxidative insults from free heme and radicals, generated from extracellular hemoglobin. The lipocalin α(1)-microglobulin (A1M) was recently shown to have reductase properties, reducing heme-proteins and other
Externí odkaz:
https://doaj.org/article/4fa763a68e954f34a5685ec78faa7971
Publikováno v:
Lakartidningen. 108(43)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad78ff841f90eb6065ee1992e49f597d
https://pubmed.ncbi.nlm.nih.gov/22167977
https://pubmed.ncbi.nlm.nih.gov/22167977
Autor:
Kaija H. Valkonen, Bo Akerström, Esko Oksanen, Vesa Virtanen, Veli Pekka Jaakola, Adrian Goldman, Tiina Tolonen, Nisse Kalkkinen
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. 62(Pt 11)
Reindeer beta-lactoglobulin (betaLG) belongs to the lipocalin superfamily. Its DNA and protein sequences have been determined and showed that it had nine residue changes from bovine betaLG. Reindeer betaLG, the structure of which was finally determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e5272e35029544a95c12dcffcf3b60
https://pubmed.ncbi.nlm.nih.gov/17057340
https://pubmed.ncbi.nlm.nih.gov/17057340
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/eeae17bc62f64d6498512354b6b33570