Serum phthalate levels and time to pregnancy in couples from Greenland, Poland and Ukraine.

Autor: Ina Olmer Specht, Jens Peter Bonde, Gunnar Toft, Christian H Lindh, Bo A G Jönsson, Kristian T Jørgensen

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0120070 (2015)

Phthalates are ubiquitous industrial chemicals that have been associated with altered reproductive function in rodents. Several human studies have reported an inverse association between male testosterone and phthalate levels. Our aim was to investig

Externí odkaz: https://doaj.org/article/124ea804944e431a834cd025391d3d61

Monoacylglycerols activate TRPV1--a link between phospholipase C and TRPV1.

Autor: Peter M Zygmunt, Anna Ermund, Pouya Movahed, David A Andersson, Charlotte Simonsen, Bo A G Jönsson, Anders Blomgren, Bryndis Birnir, Stuart Bevan, Alain Eschalier, Christophe Mallet, Ana Gomis, Edward D Högestätt

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e81618 (2013)

Phospholipase C-mediated hydrolysis of phosphatidylinositol 4,5-bisphosphate generates diacylglycerol, inositol 1,4,5-trisphosphate and protons, all of which can regulate TRPV1 activity via different mechanisms. Here we explored the possibility that

Externí odkaz: https://doaj.org/article/8dc9fcd4de7e4961b0b78813742bb4f0

TRPV1 in brain is involved in acetaminophen-induced antinociception.

Autor: Christophe Mallet, David A Barrière, Anna Ermund, Bo A G Jönsson, Alain Eschalier, Peter M Zygmunt, Edward D Högestätt

Publikováno v: PLoS ONE, Vol 5, Iss 9, p e12748 (2010)

Acetaminophen, the major active metabolite of acetanilide in man, has become one of the most popular over-the-counter analgesic and antipyretic agents, consumed by millions of people daily. However, its mechanism of action is still a matter of debate

Externí odkaz: https://doaj.org/article/0d3a139e7083454482747a8944cb98df

Occupational exposure to asphalt mixture during road paving is related to increased mitochondria DNA copy number: a cross-sectional study

Autor: Yiyi Xu, Christian H. Lindh, Bo A. G. Jönsson, Karin Broberg, Maria Albin

Publikováno v: Environmental Health, Vol 17, Iss 1, Pp 1-10 (2018)

Abstract Background Asphalt workers are exposed to polyaromatic hydrocarbons (PAHs) from hot mix asphalt via both inhalation and dermal absorption. The use of crumb rubber modified (CRM) asphalt may result in higher exposure to PAHs and more adverse

Externí odkaz: https://doaj.org/article/2e8ffa0085c04e869c00e9a27b5afc4d

Amniotic Fluid INSL3 Measured During the Critical Time Window in Human Pregnancy Relates to Cryptorchidism, Hypospadias, and Phthalate Load: A Large Case–Control Study

Autor: Ravinder Anand-Ivell, Arieh Cohen, Bent Nørgaard-Pedersen, Bo A. G. Jönsson, Jens-Peter Bonde, David M. Hougaard, Christian H. Lindh, Gunnar Toft, Morten S. Lindhard, Richard Ivell

Publikováno v: Frontiers in Physiology, Vol 9 (2018)
Anand-Ivell, R, Cohen, A, Nørgaard-Pedersen, B, Jönsson, B A G, Bonde, J-P, Hougaard, D M, Lindh, C H, Toft, G, Lindhard, M S & Ivell, R 2018, ' Amniotic Fluid INSL3 Measured During the Critical Time Window in Human Pregnancy Relates to Cryptorchidism, Hypospadias, and Phthalate Load : A Large Case-Control Study ', Frontiers in Physiology, vol. 9, 406 . https://doi.org/10.3389/fphys.2018.00406
Frontiers in Physiology

The period of the first to second trimester transition in human pregnancy represents a sensitive window for fetal organogenesis, particularly in regard to the development of the male reproductive system. This is a time of relative analytical inaccess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be7d46476e2d9578b7bee9dc3e4f067f
http://journal.frontiersin.org/article/10.3389/fphys.2018.00406/full