Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Bo‐Ying Bao"'
Publikováno v:
BMC Urology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background In recent years, Genome-Wide Association Studies (GWAS) has identified risk variants related to complex diseases, but most genetic variants have less impact on phenotypes. To solve the above problems, methods that can use variants
Externí odkaz:
https://doaj.org/article/8f7dfd50408648ea8c11d2b32defdec1
Autor:
Jun-Yan Chen, Chi-Fen Chang, Shu-Pin Huang, Chao-Yuan Huang, Chia-Cheng Yu, Victor C. Lin, Jiun-Hung Geng, Chia-Yang Li, Te-Ling Lu, Bo-Ying Bao
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-10 (2024)
Abstract Background Treatment failure following androgen deprivation therapy (ADT) presents a significant challenge in the management of advanced prostate cancer. Thus, understanding the genetic factors influencing this process could facilitate the d
Externí odkaz:
https://doaj.org/article/9f5253fa597a4c12908c3aed13fda827
Autor:
Chi-Fen Chang, Bo-Ying Bao, Yu-Mei Hsueh, Pei-Ling Chen, Li-Hsin Chang, Chia-Yang Li, Jiun-Hung Geng, Te-Ling Lu, Chao-Yuan Huang, Shu-Pin Huang
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1694 (2024)
Renal cell carcinoma (RCC) is characterized by high mortality and morbidity rates. Vav guanine nucleotide exchange factors (VAVs), crucial for signal transduction between cell membrane receptors and intracellular mediators, have been implicated in ca
Externí odkaz:
https://doaj.org/article/ccd5edfcf7b24b11a240a8f48de4e077
Autor:
Chia-Yang Li, Shu-Pin Huang, Yei-Tsung Chen, Hsin-En Wu, Wei-Chung Cheng, Chao-Yuan Huang, Chia-Cheng Yu, Victor C. Lin, Jiun-Hung Geng, Te-Ling Lu, Bo-Ying Bao
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Immunodeficiencies are genetic diseases known to predispose an individual to cancer owing to defective immunity towards malignant cells. However, the link between immunodeficiency and prostate cancer progression remains unclear. T
Externí odkaz:
https://doaj.org/article/080068cd54a84ba59a98eb5f40e9c63f
Autor:
Nishi Karunasinghe, Tsion Zewdu Minas, Bo-Ying Bao, Arier Lee, Alice Wang, Shuotun Zhu, Jonathan Masters, Megan Goudie, Shu-Pin Huang, Frank J. Jenkins, Lynnette R. Ferguson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract It is being debated whether prostate-specific antigen (PSA)-based screening effectively reduces prostate cancer mortality. Some of the uncertainty could be related to deficiencies in the age-based PSA cut-off thresholds used in screening. Cu
Externí odkaz:
https://doaj.org/article/ac887caa3c184007ba8d3136083267a8
Autor:
Yuan-Ru Chen, Shu-Chi Wang, Shu-Pin Huang, Chia-Cheng Su, Po-Len Liu, Wei-Chung Cheng, Chih-Pin Chuu, Jen-Kun Chen, Bo-Ying Bao, Cheng Hsueh Lee, Chien-Chih Ke, Hsin-En Wu, Hao-Han Chang, Hsin-Chih Yeh, Chia-Yang Li
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113929- (2022)
Bladder cancer is one of the most common malignancies of the male genitourinary urinary system. Protodioscin is a steroidal saponin with anti-cancer effects on several types of cancers; however, the anti-cancer activities of protodioscin on bladder c
Externí odkaz:
https://doaj.org/article/c641437be54b47ca8ec66a6f8a73e383
Autor:
Chia‐Cheng Yu, Lih‐Chyang Chen, Chao‐Yuan Huang, Victor C. Lin, Te‐Ling Lu, Cheng‐Hsueh Lee, Shu‐Pin Huang, Bo‐Ying Bao
Publikováno v:
Cancer Medicine, Vol 9, Iss 7, Pp 2372-2378 (2020)
Abstract Anoctamins were originally identified as a family of calcium‐activated chloride channels, but recently their roles in the development of different types of malignancies were suggested. Here, we evaluated the associations between 211 common
Externí odkaz:
https://doaj.org/article/2b6034e12f4b4a8383676b2dafdb0fe7
Autor:
Chia‐Cheng Yu, Lih‐Chyang Chen, Victor C. Lin, Chao‐Yuan Huang, Wei‐Chung Cheng, Ai‐Ru Hsieh, Ta‐Yuan Chang, Te‐Ling Lu, Cheng‐Hsueh Lee, Shu‐Pin Huang, Bo‐Ying Bao
Publikováno v:
Cancer Medicine, Vol 8, Iss 6, Pp 2777-2783 (2019)
Abstract The aberrant expression of cell adhesion molecules is a hallmark of epithelial‐to‐mesenchymal transition, resulting in the transformation of cancer cells to a more aggressive phenotype. This study investigated the association between gen
Externí odkaz:
https://doaj.org/article/816ef331204a4ba89cdc1e3ca9ed16e8
Autor:
Chia-Cheng Yu, Lih-Chyang Chen, Chih-Yung Chiou, Yu-Jia Chang, Victor C. Lin, Chao-Yuan Huang, I-Ling Lin, Ta-Yuan Chang, Te-Ling Lu, Cheng-Hsueh Lee, Shu-Pin Huang, Bo-Ying Bao
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background To determine the association between circadian pathway genetic variants and the risk of prostate cancer progression. Methods We systematically evaluated 79 germline variants in nine circadian pathway genes in a cohort of 458 patie
Externí odkaz:
https://doaj.org/article/c74ff266e82c4e078c57e3dd84528f6a
Autor:
Shu-Pin Huang, Yei-Tsung Chen, Lih-Chyang Chen, Cheng-Hsueh Lee, Chao-Yuan Huang, Chia-Cheng Yu, Victor C. Lin, Te-Ling Lu, Bo-Ying Bao
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 528 (2021)
Neuregulins (NRGs) activate receptor tyrosine kinases of the ErbB family, and play essential roles in the proliferation, survival, and differentiation of normal and malignant tissue cells. We hypothesized that genetic variants of NRG signalling pathw
Externí odkaz:
https://doaj.org/article/6b573b34869f4722938b1d01cbf4b183