Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Bo‐Syong Pan"'
Autor:
Meng-Chieh Lin, Guan-Yu Chen, Hsin-Hsien Yu, Pei-Ling Hsu, Chu-Wan Lee, Chih-Cheng Cheng, Shih-Ying Wu, Bo-Syong Pan, Bor-Chyuan Su
Publikováno v:
Bone & Joint Research, Vol 13, Iss 4, Pp 157-168 (2024)
Aims: Osteosarcoma is the most common primary bone malignancy among children and adolescents. We investigated whether benzamil, an amiloride analogue and sodium-calcium exchange blocker, may exhibit therapeutic potential for osteosarcoma in vitro. Me
Externí odkaz:
https://doaj.org/article/022c4816a2b247feaab0c91e6568f1fe
Autor:
Bor-Chyuan Su, Guan-Yu Chen, Chun-Ming Yang, Wei-Ting Chuang, Meng-Chieh Lin, Pei-Ling Hsu, Chu-Wan Lee, Chih-Cheng Cheng, Shih-Ying Wu, Bo-Syong Pan, Hsin-Hsien Yu
Publikováno v:
International Journal of Hyperthermia, Vol 41, Iss 1 (2024)
AbstractObjective: Gastric cancer with peritoneal metastasis is considered to be final stage gastric cancer. One current treatment approach for this condition is combined cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC). H
Externí odkaz:
https://doaj.org/article/7e11e6d856f549419c5afef5b0e23846
Autor:
Chuan Xu, Guoxiang Jin, Hong Wu, Wei Cui, Yu-Hui Wang, Rajesh Kumar Manne, Guihua Wang, Weina Zhang, Xian Zhang, Fei Han, Zhen Cai, Bo-Syong Pan, Che-Chia Hsu, Yiqiang Liu, Anmei Zhang, Jie Long, Hongbo Zou, Shuang Wang, Xiaodan Ma, Jinling Duan, Bin Wang, Weihui Liu, Haitao Lan, Qing Xiong, Gang Xue, Zhongzhu Chen, Zhigang Xu, Mark E. Furth, Sarah Haigh Molina, Yong Lu, Dan Xie, Xiu-Wu Bian, Hui-Kuan Lin
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 5 (2022)
Cancer stem-like cells (CSLCs) acquire enhanced immune checkpoint responses to evade immune cell killing and promote tumor progression. Here we showed that signal regulatory protein γ (SIRPγ) determined CSLC properties and immune evasiveness in a s
Externí odkaz:
https://doaj.org/article/ed9d232ee19b4520b69e25795aaa76fb
Autor:
Shih-Ying Wu, Bo-Syong Pan, Sheng-Feng Tsai, Yi-Ting Chiang, Bu-Miin Huang, Fan-E Mo, Yu-Min Kuo
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Abstract Background Excessive microglial activation is implicated in the pathogenesis of various age-related neurodegenerative diseases. In addition to neurons, brain-derived neurotrophic factor (BDNF) and its receptor TrkB are also expressed in micr
Externí odkaz:
https://doaj.org/article/19cb44ff6cf84bbdac8a2ae7dd1a5b28
Publikováno v:
Cancer Medicine, Vol 8, Iss 8, Pp 3949-3964 (2019)
Abstract Testicular cancer is the most commonly diagnosed cancer in men at 15‐44 years of age, and radical orchidectomy combined with chemotherapy is currently considered as the standard treatment. However, drugs resistance and side effects that im
Externí odkaz:
https://doaj.org/article/baf126ff6c4146d58e8832f9c14c87a7
Publikováno v:
Cells, Vol 11, Iss 3, p 481 (2022)
Parkinson’s disease (PD) is an age-related neurodegenerative disease caused by a selective loss of dopaminergic (DA) neurons in the substantia nigra (SN). Microglial activation is implicated in the pathogenesis of PD. This study aimed to characteri
Externí odkaz:
https://doaj.org/article/9c2c14d70c0548fdaea88cd2c6ae9360
Autor:
Xian Zhang, Binkui Li, Abdol Hossein Rezaeian, Xiaohong Xu, Ping-Chieh Chou, Guoxiang Jin, Fei Han, Bo-Syong Pan, Chi-Yun Wang, Jie Long, Anmei Zhang, Chih-Yang Huang, Fuu-Jen Tsai, Chang-Hai Tsai, Christopher Logothetis, Hui-Kuan Lin
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Histone modifications play important roles in gene transcription and cancer. Here the authors establish a role for the E3 ubiquitin ligase NEDD4 in modifying in a glucose-dependent manner the histone H3, thus regulating the expression of genes involv
Externí odkaz:
https://doaj.org/article/08472bddebdd4affaebf25d8c71e5057
Autor:
Bo-Syong Pan, 潘博雄
95
Cordycepin (3’ deoxyadenosine), the analogue of adenosine, is a pure component extracted from the mycelia of Cordyceps sinensis. It has been suggested that cordycepin can improve lung function and increase energy levels and sex drive. Our l
Cordycepin (3’ deoxyadenosine), the analogue of adenosine, is a pure component extracted from the mycelia of Cordyceps sinensis. It has been suggested that cordycepin can improve lung function and increase energy levels and sex drive. Our l
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/96714669448184169098
Publikováno v:
ACS Omega. 7:26015-26021
PROTACs represent a promising modality that has gained significant attention for the treatment of cancer, Alzheimer's disease, and so forth. Due to limited structural information of the POI-PROTAC-E3 ligase ternary complex, the discovery of active PR
Autor:
Rajni Kant, Rajesh Kumar Manne, Mohammad Anas, Vasudevarao Penugurti, Tingjin Chen, Bo-Syong Pan, Che-Chia Hsu, Hui-Kuan Lin
Publikováno v:
Seminars in cancer biology. 86(Pt 3)
Metabolic reprogramming is an important cancer hallmark that plays a key role in cancer malignancies and therapy resistance. Cancer cells reprogram the metabolic pathways to generate not only energy and building blocks but also produce numerous key s