Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Bożena Bruhn-Olszewska"'
Autor:
Magdalena Wójcik, Ulana Juhas, Elyas Mohammadi, Jonas Mattisson, Kinga Drężek-Chyła, Edyta Rychlicka-Buniowska, Bożena Bruhn-Olszewska, Hanna Davies, Katarzyna Chojnowska, Paweł Olszewski, Michał Bieńkowski, Michał Jankowski, Olga Rostkowska, Andrzej Hellmann, Rafał Pęksa, Jacek Kowalski, Marek Zdrenka, Jarek Kobiela, Wojciech Zegarski, Wojciech Biernat, Łukasz Szylberg, Piotr Remiszewski, Jakub Mieczkowski, Natalia Filipowicz, Jan P. Dumanski
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Male sex is a risk factor for colorectal cancer (CRC) with higher illness burden and earlier onset. Thus, we hypothesized that loss of chromosome Y (LOY) in the tumor micro-environment (TME) might be involved in oncogenesis. Previous studies
Externí odkaz:
https://doaj.org/article/7d9a04b0e6d44884bfeda7d025cf4b9a
Autor:
Jonas Mattisson, Jonatan Halvardson, Hanna Davies, Bożena Bruhn-Olszewska, Paweł Olszewski, Marcus Danielsson, Josefin Bjurling, Amanda Lindberg, Ammar Zaghlool, Edyta Rychlicka-Buniowska, Jan P. Dumanski, Lars A. Forsberg
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Mosaic loss of chromosome Y (LOY) in leukocytes is the most prevalent somatic aneuploidy in aging humans. Men with LOY have increased risks of all-cause mortality and the major causes of death, including many forms of cancer. It h
Externí odkaz:
https://doaj.org/article/3fb79618f8b24d1694b937e0dfc03697
Autor:
Bożena Bruhn-Olszewska, Hanna Davies, Daniil Sarkisyan, Ulana Juhas, Edyta Rychlicka-Buniowska, Magdalena Wójcik, Monika Horbacz, Marcin Jąkalski, Paweł Olszewski, Jakub O. Westholm, Agata Smialowska, Karol Wierzba, Åsa Torinsson Naluai, Niklas Jern, Lars-Magnus Andersson, Josef D. Järhult, Natalia Filipowicz, Eva Tiensuu Janson, Sten Rubertsson, Miklós Lipcsey, Magnus Gisslén, Michael Hultström, Robert Frithiof, Jan P. Dumanski
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-14 (2022)
Abstract Background The COVID-19 pandemic, which has a prominent social and economic impact worldwide, shows a largely unexplained male bias for the severity and mortality of the disease. Loss of chromosome Y (LOY) is a risk factor candidate in COVID
Externí odkaz:
https://doaj.org/article/47e00c830df04f0b876d13cf816381e5
Autor:
Katarzyna Potrykus, Nathan E. Thomas, Bożena Bruhn-Olszewska, Michał Sobala, Maciej Dylewski, Tamara James, Michael Cashel
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The Mesh1 class of hydrolases found in bacteria, metazoans and humans was discovered as able to cleave an intact pyrophosphate residue esterified on the 3′hydroxyl of (p)ppGpp in a Mn2+ dependent reaction. Here, thin layer chromatography (TLC) qual
Externí odkaz:
https://doaj.org/article/6ce7aa90bc7e491cb21d7576de2d686e
Autor:
Bartosz Kamil Sobocki, Charbel A. Basset, Bożena Bruhn-Olszewska, Paweł Olszewski, Olga Szot, Karolina Kaźmierczak-Siedlecka, Mateusz Guziak, Luigi Nibali, Angelo Leone
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 970 (2022)
Periodontitis is prevalent in half of the adult population and raises critical health concerns as it has been recently associated with an increased risk of cancer. While information about the topic remains somewhat scarce, a deeper understanding of t
Externí odkaz:
https://doaj.org/article/e9f841a2d21f4f55a8b692159e8d6b3a
Autor:
Bożena Bruhn-Olszewska, Anna Korzon-Burakowska, Grzegorz Węgrzyn, Joanna Jakóbkiewicz-Banecka
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Charcot arthropathy is one of the most serious complications of diabetic foot syndrome that leads to amputation of the affected limb. Since there is no cure for Charcot arthropathy, early diagnosis and implementation preventive care are the
Externí odkaz:
https://doaj.org/article/a0749f39c6fa4cefb935b5c24a69437d
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
In bacteria, the so-called stringent response is responsible for adaptation to changing environmental conditions. This response is mediated by guanosine derivatives [(p)ppGpp], synthesized by either large mono-functional RelA or bi-functional SpoT (s
Externí odkaz:
https://doaj.org/article/b966185807e043bb8d832a261b299785
Autor:
Maciej Dylewski, Llorenç Fernández-Coll, Bożena Bruhn-Olszewska, Carlos Balsalobre, Katarzyna Potrykus
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5224 (2019)
GreA is a well-characterized transcriptional factor that acts primarily by rescuing stalled RNA polymerase complexes, but has also been shown to be the major transcriptional fidelity and proofreading factor, while it inhibits DNA break repair. Regula
Externí odkaz:
https://doaj.org/article/29f9c8ac039d4e16a6da175b977bef2f
Publikováno v:
Hydrobiologia. 847:2503-2519
Rapid development of high-throughput sequencing methods and metagenomics revealed a diverse world of microbiota associated with multicellular organisms. Although recent discoveries indicate that freshwater invertebrates are hosts for specific bacteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1a38292ce6bcaba17d8b87e101c2bd9
https://doi.org/10.1007/s10750-020-04269-z
https://doi.org/10.1007/s10750-020-04269-z
Publikováno v:
Postępy Biochemii. 64:1-8
About 50 years ago, „magic spots” â mediators of the bacterial stringent response, were discovered and were later identified as guanosine tetra- and pentaphosphate (ppGpp and pppGpp, jointly referred to as (p)ppGpp). At first, it seemed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b3841d9927ce14416f3955ac8fcb211
https://doi.org/10.18388/pb.2018_93
https://doi.org/10.18388/pb.2018_93