Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Bożena, Jarosz"'
Autor:
Renata Duchnowska, Anna Maria Supernat, Rafał Pęksa, Marta Łukasiewicz, Tomasz Stokowy, Roy Ronen, Janusz Dutkowski, Monika Umińska, Ewa Iżycka-Świeszewska, Anna Kowalczyk, Waldemar Och, Monika Rucińska, Wojciech P. Olszewski, Tomasz Mandat, Bożena Jarosz, Michał Bieńkowski, Wojciech Biernat, Jacek Jassem
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Brain metastases (BMs) in ovarian cancer (OC) are a rare event. BMs occur most frequently in high-grade serous (HGS) OC. The molecular features of BMs in HGSOC are poorly understood. We performed a whole-exome sequencing analysis of ten matc
Externí odkaz:
https://doaj.org/article/d2d11a695913453e8ed1c77cf42a380f
Autor:
Anna Grenda, Ewelina Iwan, Izabela Chmielewska, Paweł Krawczyk, Aleksandra Giza, Arkadiusz Bomba, Małgorzata Frąk, Anna Rolska, Michał Szczyrek, Robert Kieszko, Tomasz Kucharczyk, Bożena Jarosz, Dariusz Wasyl, Janusz Milanowski
Publikováno v:
AMB Express, Vol 12, Iss 1, Pp 1-7 (2022)
Key points Composition of the microbiome can influence patients response to immunotherapy Response to immunotherapy of NSCLC patients is associated with the presence of Akkermansiaceae in the gut Akkermansia could be used as a predictor for patient t
Externí odkaz:
https://doaj.org/article/18beb8b224e645819cdd58155b18d256
Autor:
Marcin Nicoś, PhD, Luuk Harbers, MSc, Enrico Patrucco, PhD, Maximilian Kramer-Drauberg, PhD, Xiaolu Zhang, PhD, Claudia Voena, PhD, Anna Kowalczyk, MD, PhD, Aleksandra Bożyk, PhD, Rafał Pęksa, MD, PhD, Bożena Jarosz, MD, PhD, Justyna Szumiło, MD, Michele Simonetti, PhD, Monika Żuk, PhD, Bartosz Wasąg, MD, Katarzyna Reszka, PhD, Renata Duchnowska, MD, Janusz Milanowski, MD, Roberto Chiarle, MD, Magda Bienko, PhD, Paweł Krawczyk, MD, Jacek Jassem, MD, Chiara Ambrogio, PhD, Nicola Crosetto, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 12, Pp 100435- (2022)
Introduction: Brain metastases (BM) severely affect the prognosis and quality of life of patients with NSCLC. Recently, molecularly targeted agents were found to have promising activity against BM in patients with NSCLC whose primary tumors carry “
Externí odkaz:
https://doaj.org/article/93978b32039848998a35af7844ee33cf
Autor:
Paweł Krawczyk, Anna Grenda, Paulina Terlecka, Justyna Błach, Kamila Wojas-Krawczyk, Tomasz Kucharczyk, Izabela Chmielewska, Robert Kieszko, Bożena Jarosz, Michał Gil, Katarzyna Reszka, Janusz Milanowski
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract In patients with advanced non-small cell lung cancer (NSCLC), comprehensive genetic diagnostics is currently carried out in order to qualify for molecularly targeted therapies and immunotherapy. The aim of the study was to assess the usefuln
Externí odkaz:
https://doaj.org/article/0b0280e474be480fb01bad2628801426
Autor:
Paulina Kozakiewicz, Ludmiła Grzybowska-Szatkowska, Marzanna Ciesielka, Paulina Całka, Jacek Osuchowski, Paweł Szmygin, Bożena Jarosz, Marta Ostrowska-Leśko, Jarosław Dudka, Angelika Tkaczyk-Wlizło, Brygida Ślaska
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1183 (2023)
Mitochondria are organelles necessary for oxidative phosphorylation. The interest in the role of mitochondria in the process of carcinogenesis results from the fact that a respiratory deficit is found in dividing cells, especially in cells with accel
Externí odkaz:
https://doaj.org/article/6841a5ba27524d31a3a91eefb1930da0
Autor:
Paulina Kozakiewicz, Ludmiła Grzybowska-Szatkowska, Marzanna Ciesielka, Paulina Całka, Jacek Osuchowski, Paweł Szmygin, Bożena Jarosz, Brygida Ślaska
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12131 (2022)
Mitochondrial DNA changes can contribute to both an increased and decreased likelihood of cancer. This process is complex and not fully understood. Polymorphisms and mutations, especially those of the missense type, can affect mitochondrial functions
Externí odkaz:
https://doaj.org/article/4ec7a49460ba418d9145be035cfeaf5f
Autor:
Anna Grenda, Paweł Krawczyk, Justyna Błach, Izabela Chmielewska, Tomasz Kubiatowski, Stanisław Kieszko, Kamila Wojas-Krawczyk, Tomasz Kucharczyk, Bożena Jarosz, Iwona Paśnik, Małgorzata Borowiec-Bar, Małgorzata Frąk, Robert Kieszko, Michał Szczyrek, Katarzyna Reszka, Kinga Krukowska, Agnieszka Kolak, Sławomir Mańdziuk, Dariusz Kowalski, Marek Sawicki, Daria Świniuch, Elżbieta Starosławska, Rodryg Ramlau, Justyna Szumiło, Maciej Krzakowski, Janusz Milanowski
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
IntroductionExpression of PD-L1 protein on tumor cells, which is so far the only validated predictive factor for immunotherapy, is regulated by epigenetic and genetic factors. Among the most important ones that regulate gene expression are microRNAs.
Externí odkaz:
https://doaj.org/article/c993130ac66d46a888f3466869076bb7
Autor:
Dariusz Szczepanek, Justyna Szumiło, Filip Stoma, Agnieszka Szymczyk, Bożena Jarosz, Aleksandra Szczepanek, Marek Hus, Tomasz Trojanowski, Ewa Wasik-Szczepanek
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
The involvement of the central nervous system (CNS) in Hodgkin lymphoma (HL) has been rarely reported, especially in its primary isolated form. Herein, we present a case of a 33-year-old woman, who received immunosuppressive treatment due to ulcerati
Externí odkaz:
https://doaj.org/article/ff8d51c2323b4a458fb80b108d3c9755
Autor:
Adrian Odrzywolski, Bożena Jarosz, Michał Kiełbus, Ilona Telejko, Dominik Ziemianek, Sebastian Knaga, Radosław Rola
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13217 (2021)
Glioblastoma (GBM) remains the leading cause of cancer-related deaths with the lowest five-year survival rates among all of the human cancers. Multiple factors contribute to its poor outcome, including intratumor heterogeneity, along with migratory a
Externí odkaz:
https://doaj.org/article/49ac1448fc7b4ec1a8f8f105a49d838c
Autor:
Anna Grenda, Ewelina Iwan, Paweł Krawczyk, Małgorzata Frąk, Izabela Chmielewska, Arkadiusz Bomba, Aleksandra Giza, Anna Rolska-Kopińska, Michał Szczyrek, Robert Kieszko, Tomasz Kucharczyk, Bożena Jarosz, Dariusz Wasyl, Janusz Milanowski
Publikováno v:
Cancers; Volume 14; Issue 24; Pages: 6250
Introduction: Factors other than PD-L1 (Programmed Death Ligand 1) are being sought as predictors for cancer immuno- or chemoimmunotherapy in ongoing studies and long-term observations. Despite high PD-L1 expression on tumor cells, some patients do n