Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Boštjan Rituper"'
Autor:
Maja Žugec, Borut Furlani, Maria J. Castañon, Boštjan Rituper, Irmgard Fischer, Giuseppe Broggi, Rosario Caltabiano, Giuseppe M. V. Barbagallo, Michelino Di Rosa, Daniele Tibullo, Rosalba Parenti, Nunzio Vicario, Saša Simčič, Victorio Martin Pozo Devoto, Gorazd B. Stokin, Gerhard Wiche, Jernej Jorgačevski, Robert Zorec, Maja Potokar
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-22 (2024)
Abstract Background The expression of aquaporin 4 (AQP4) and intermediate filament (IF) proteins is altered in malignant glioblastoma (GBM), yet the expression of the major IF-based cytolinker, plectin (PLEC), and its contribution to GBM migration an
Externí odkaz:
https://doaj.org/article/32ce5b5e6d344a77a4c23f8a8c7dcde0
Autor:
Julij Šelb, Barbara Bitežnik, Urška Bidovec Stojković, Boštjan Rituper, Katarina Osolnik, Peter Kopač, Petra Svetina, Kristina Cerk Porenta, Franc Šifrer, Petra Lorber, Darinka Trinkaus Leiler, Tomaž Hafner, Tina Jerič, Robert Marčun, Nika Lalek, Nina Frelih, Mojca Bizjak, Rok Lombar, Vesna Nikolić, Katja Adamič, Katja Mohorčič, Sanja Grm Zupan, Irena Šarc, Jerneja Debeljak, Ana Koren, Ajda Demšar Luzar, Matija Rijavec, Izidor Kern, Matjaž Fležar, Aleš Rozman, Peter Korošec
Publikováno v:
ERJ Open Research, Vol 8, Iss 4 (2022)
Background The relationship between anti-SARS-CoV-2 humoral immune response, pathogenic inflammation, lymphocytes and fatal COVID-19 is poorly understood. Methods A longitudinal prospective cohort of hospitalised patients with COVID-19 (n=254) was fo
Externí odkaz:
https://doaj.org/article/14f64924f672446c9df02f3f83544b15
Autor:
Eva Lasič, Prabhodh S. Abbineni, Alenka Guček, Gregor Anderluh, Bojan Božič, Marjeta Lisjak, Boštjan Rituper, Frances M. Platt, Aleksandra Šakanović, Jernej Jorgačevski, Saša Trkov Bobnar, Marko Kreft, Matjaž Stenovec, Urszula Górska, Alexei Verkhratsky, Mićo Božić, Robert Zorec, Jens R. Coorssen
Publikováno v:
Cell calcium, vol. 101, 102503, 2022.
In some lysosomal storage diseases (LSD) cholesterol accumulates in vesicles. Whether increased vesicle cholesterol affects vesicle fusion with the plasmalemma, where the fusion pore, a channel between the vesicle lumen and the extracellular space, i
Autor:
Prabhodh S. Abbineni, Coorssen, Boštjan Rituper, Frances M. Platt, Eva Lasič, Marjeta Lisjak, Alex Verkhratsky, Borut Božič, Urszula Górska, Matjaž Stenovec, Mateja Erdani Kreft, Jernej Jorgačevski, Aleksandra Šakanović, Alenka Guček, Gregor Anderluh, Saša Trkov Bobnar, Mićo Božić, Robert Zorec
Eukaryotic vesicles fuse with the plasmalemma to form the fusion pore, previously considered to be unstable with widening of the pore diameter. Recent studies established that the pore diameter is stable, reflecting balanced forces of widening and cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68542cfef03523ea4dad4c8cabde1848
https://doi.org/10.1101/2020.04.06.027169
https://doi.org/10.1101/2020.04.06.027169
Subanesthetic doses of ketamine stabilize the fusion pore in a narrow flickering state in astrocytes
Publikováno v:
Journal of Neurochemistry. 138:909-917
Ketamine is an anesthetic that exhibits analgesic, psychotomimetic, and rapid antidepressant effects that are of particular neuropharmacological interest. Recent studies revealed astrocytic Ca(2+) signaling and regulated exocytosis as ketamine-target
Publikováno v:
Channels. 9:96-101
In regulated exocytosis vesicular and plasma membranes merge to form a fusion pore in response to stimulation. The nonselective cation HCN channels are involved in the regulation of unitary exocytotic events by at least 2 mechanisms. They can affect
Autor:
Jernej Jorgačevski, Robert Zorec, Helena H. Chowdhury, Boštjan Rituper, Marko Kreft, Jens R. Coorssen
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1831:1228-1238
How cholesterol, a key membrane constituent, affects membrane surface area dynamics in secretory cells is unclear. Using methyl-beta-cyclodextrin (MbetaCD) to deplete cholesterol, we imaged melanotrophs from male Wistar rats in real-time and monitore
Publikováno v:
Nature Protocols. 8:1169-1183
In order to understand exocytosis and endocytosis, it is necessary to study these processes directly. An elegant way to do this is by measuring plasma membrane capacitance (C(m)), a parameter proportional to cell surface area, the fluctuations of whi
Publikováno v:
Cell Calcium. 52:250-258
Since the 1970s, much effort was been expended researching mechanisms of regulated exocytosis. Early work focused mainly on the role of proteins. Most notably the discovery of SNARE proteins in the 1980s and the zippering hypothesis brought us much c
Publikováno v:
Clinical Lipidology. 5:747-761
Exocytosis is a highly conserved and ubiquitous process of eukaryotic cells responsible for the release of signaling molecules into extracellular space. Exocytosis involves trafficking, docking and eventually fusion of vesicles, carrying various carg