Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Bo, Lundgren"'
Publikováno v:
Environment International, Vol 192, Iss , Pp 108991- (2024)
Chemical risk assessments typically focus on single substances, often overlooking real-world co-exposures to chemical mixtures. Mixture toxicology studies using representative mixtures can reveal potential chemical interactions, but these do not acco
Externí odkaz:
https://doaj.org/article/9f1c1a334bd94434bff5bcbfb1251bc2
Autor:
Helena Montanuy, Cristina Camps-Fajol, Jordi Carreras-Puigvert, Maria Häggblad, Bo Lundgren, Miriam Aza-Carmona, Thomas Helleday, Jordi Minguillón, Jordi Surrallés
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-9 (2020)
Abstract Background Fanconi anemia is a rare disease clinically characterized by malformations, bone marrow failure and an increased risk of solid tumors and hematologic malignancies. The only therapies available are hematopoietic stem cell transplan
Externí odkaz:
https://doaj.org/article/64abf667360445cfaf72bee11ee1388b
Autor:
Patrik Johansson, Cecilia Krona, Soumi Kundu, Milena Doroszko, Sathishkumar Baskaran, Linnéa Schmidt, Claire Vinel, Elin Almstedt, Ramy Elgendy, Ludmila Elfineh, Caroline Gallant, Sara Lundsten, Fernando J. Ferrer Gago, Aleksi Hakkarainen, Petra Sipilä, Maria Häggblad, Ulf Martens, Bo Lundgren, Melanie M. Frigault, David P. Lane, Fredrik J. Swartling, Lene Uhrbom, Marika Nestor, Silvia Marino, Sven Nelander
Publikováno v:
Cell Reports, Vol 32, Iss 2, Pp 107897- (2020)
Summary: Glioblastoma (GBM) is a malignant brain tumor with few therapeutic options. The disease presents with a complex spectrum of genomic aberrations, but the pharmacological consequences of these aberrations are partly unknown. Here, we report an
Externí odkaz:
https://doaj.org/article/cc573e6ed9f44191ba0a80782a5d717e
Autor:
Amir Ata Saei, Hjalmar Gullberg, Pierre Sabatier, Christian M. Beusch, Katarina Johansson, Bo Lundgren, Per I. Arvidsson, Elias S.J. Arnér, Roman A. Zubarev
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
Chemical proteomics encompasses novel drug target deconvolution methods in which compound modification is not required. Herein we use Thermal Proteome Profiling, Functional Identification of Target by Expression Proteomics and multiplexed redox prote
Externí odkaz:
https://doaj.org/article/66852d1ff08741ec855db8d5f4ff457f
A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family
Autor:
Jordi Carreras-Puigvert, Marinka Zitnik, Ann-Sofie Jemth, Megan Carter, Judith E. Unterlass, Björn Hallström, Olga Loseva, Zhir Karem, José Manuel Calderón-Montaño, Cecilia Lindskog, Per-Henrik Edqvist, Damian J. Matuszewski, Hammou Ait Blal, Ronnie P. A. Berntsson, Maria Häggblad, Ulf Martens, Matthew Studham, Bo Lundgren, Carolina Wählby, Erik L. L. Sonnhammer, Emma Lundberg, Pål Stenmark, Blaz Zupan, Thomas Helleday
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
The NUDIX hydrolases are known to be involved in several cellular processes and diseases, such as cancer, but remain poorly characterized as a family. Here, the authors provide a comprehensive analysis of the structural, biochemical, and expression p
Externí odkaz:
https://doaj.org/article/6564fe588369406e87c0d1e279e7b8c4
Publikováno v:
Endocrine Abstracts.
Autor:
Andreas Luttens, Hjalmar Gullberg, Eldar Abdurakhmanov, Duy Duc Vo, Dario Akaberi, Vladimir O. Talibov, Natalia Nekhotiaeva, Laura Vangeel, Steven De Jonghe, Dirk Jochmans, Janina Krambrich, Ali Tas, Bo Lundgren, Ylva Gravenfors, Alexander J. Craig, Yoseph Atilaw, Anja Sandström, Lindon W. K. Moodie, Åke Lundkvist, Martijn J. van Hemert, Johan Neyts, Johan Lennerstrand, Jan Kihlberg, Kristian Sandberg, U. Helena Danielson, Jens Carlsson
Publikováno v:
Journal of the American Chemical Society, 144(7), 2905-2920. AMER CHEMICAL SOC
Drugs targeting SARS-CoV-2 could have saved millions of lives during the COVID-19 pandemic, and it is now crucial to develop inhibitors of coronavirus replication in preparation for future outbreaks. We explored two virtual screening strategies to fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946c3c3e10aa0c690988b970c049d161
http://hdl.handle.net/1887/3479854
http://hdl.handle.net/1887/3479854
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148721 (2016)
Externí odkaz:
https://doaj.org/article/1178b77bda4a4da18276aa6be1934a0f
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70668 (2013)
Knowledge of the spatial distribution of juvenile cod is essential for obtaining precise recruitment data to conduct sustainable management of the eastern and western Baltic cod stocks. In this study, the horizontal and vertical distribution and dens
Externí odkaz:
https://doaj.org/article/a0ef5d6004cf48b8b588433f6e684e10
Autor:
Christian M. Beusch, Hjalmar Gullberg, Katarina Johansson, Bo Lundgren, Amir Ata Saei, Pierre Sabatier, Per I. Arvidsson, Elias S.J. Arnér, Roman A. Zubarev
Publikováno v:
Redox Biology, Vol 32, Iss, Pp-(2020)
Redox Biology
Redox Biology
Chemical proteomics encompasses novel drug target deconvolution methods in which compound modification is not required. Herein we use Thermal Proteome Profiling, Functional Identification of Target by Expression Proteomics and multiplexed redox prote