Zobrazeno 1 - 10
of 66
pro vyhledávání: '"BmrA"'
Autor:
Nupur Mukherjee, Alacoque Browne, Laura Ivers, Tapesh Santra, Mattia Cremona, Bryan T. Hennessy, Norma O’Donovan, John Crown, Walter Kolch, Dirk Fey, Alex J. Eustace
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 8; Pages: 1277
Triple negative breast cancer (TNBC) remains a therapeutic challenge due to the lack of targetable genetic alterations and the frequent development of resistance to the standard cisplatin-based chemotherapies. Here, we have taken a systems biology ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f1c2bb8eb1882d93b78a0dfdf5f4e4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5239
The folding and stability of proteins are often studied via unfolding (and refolding) a protein with urea. Yet, in the case of membrane integral protein domains, which are shielded by a membrane or a membrane mimetic, urea generally does not induce u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373289e45f3c46b4fdf969f00521e2bb
https://doi.org/10.3390/ijms24065239
https://doi.org/10.3390/ijms24065239
Autor:
Kristin Oepen, Hüseyin Özbek, Anja Schüffler, Johannes C. Liermann, Eckhard Thines, Dirk Schneider
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13565
International Journal of Molecular Sciences, Vol 22, Iss 13565, p 13565 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13565
International Journal of Molecular Sciences, Vol 22, Iss 13565, p 13565 (2021)
ATP-binding cassette (ABC) transporters are conserved in all kingdoms of life, where they transport substrates against a concentration gradient across membranes. Some ABC transporters are known to cause multidrug resistances in humans and are able to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e99f3e6190e7879d06d0f0b6fc40c0d
http://europepmc.org/articles/PMC8707315
http://europepmc.org/articles/PMC8707315
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Britta eKunert, Carole eGardiennet, Denis eLacabanne, Daniel eCalles-Garcia, Pierre eFalson, Jean-Michel eJault, Beat H Meier, Penin eFrancois, Anja eBöckmann
Publikováno v:
Frontiers in Molecular Biosciences, Vol 1 (2014)
We present solid-state NMR sample preparation and first 2D spectra of the Bacillus subtilis ATP-binding cassette transporter BmrA, a membrane protein involved in multidrug resistance. The homodimeric 130-kDa protein is a challenge for structural char
Externí odkaz:
https://doaj.org/article/af001a35af1f44a498e9b09af67f9f0c
Autor:
Duygu Senturk, Berna Sariyar Akbulut, Jean-Michel Jault, Fatma Ece Altinisik Kaya, Pemra Ozbek, Tihomir Tomašič, Rok Frlan, Onur Serçinoğlu, Fatma Gizem Avci, Cédric Orelle
Publikováno v:
Bioorganic Chemistry
Bioorganic Chemistry, Elsevier, 2020, 105, pp.104452. ⟨10.1016/j.bioorg.2020.104452⟩
Bioorganic Chemistry, Elsevier, 2020, 105, pp.104452. ⟨10.1016/j.bioorg.2020.104452⟩
International audience; The resistance of microbes to commonly used antibiotics has become a worldwide health problem. A major underlying mechanism of microbial antibiotic resistance is the export of drugs from bacterial cells. Drug efflux is mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0d518ad17d435904cf27cc601b9e5a
https://hal.archives-ouvertes.fr/hal-03200521
https://hal.archives-ouvertes.fr/hal-03200521
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Javed, Waqas
Publikováno v:
Structural Biology [q-bio.BM]. Université Grenoble Alpes [2020-..], 2020. English. ⟨NNT : 2020GRALV046⟩
Antibiotic resistance is not the story of the future but a reality today. Bacterial resistance to antibiotics can be conferred by several mechanisms, including the overexpression of dedicated efflux pumps, some of them belonging to the ABC (“ATP-bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8038853552de624bc725962a6afc3d0d
https://theses.hal.science/tel-03362700
https://theses.hal.science/tel-03362700
Autor:
Zampieri, Veronica
The antibiotic resistance is classified as a major human health threat by the World Health Organization (WHO) mainly due to a misuse of these compounds. Bacteria can adopt the different molecular mechanisms and one of them is the efflux of the compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______166::250c31d8d1810191729a38e15d204af1
https://theses.hal.science/tel-03538210
https://theses.hal.science/tel-03538210