Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Blythe H Devlin"'
Autor:
Adriana S Albuquerque, José G Marques, Susana L Silva, Dario Ligeiro, Blythe H Devlin, Jacques Dutrieux, Rémi Cheynier, Claudio Pignata, Rui M M Victorino, M Louise Markert, Ana E Sousa
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37042 (2012)
Forkhead box N1 (FOXN1) is a transcription factor crucial for thymic epithelium development and prevention of its involution. Investigation of a patient with a rare homozygous FOXN1 mutation (R255X), leading to alopecia universalis and thymus aplasia
Externí odkaz:
https://doaj.org/article/9f3b322d36ec49c49ade3fd6d5172c7d
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 6, p e1000396 (2009)
T cell populations are regulated both by signals specific to the T-cell receptor (TCR) and by signals and resources, such as cytokines and space, that act independently of TCR specificity. Although it has been demonstrated that disruption of either o
Externí odkaz:
https://doaj.org/article/bb0e51bf6af4459cb9307e3de6dac77e
Autor:
Jeffrey M. Gimble, Yuan Di C. Halvorsen, Farshid Guilak, Laura Aust, William O. Wilkison, Amy Kloster, Blythe H. Devlin, Sandra J. Foster, Tracey V. Du Laney, Kevin C. Hicok, Robert W. Storms, Anindita Sen, Lyndon F. Cooper, Henry E. Rice
Publikováno v:
Stem Cell Therapy for Autoimmune Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f1dfca6ed006ecc992e8cfa65d83916
https://doi.org/10.1201/9780367813895-5
https://doi.org/10.1201/9780367813895-5
Publikováno v:
American Journal of Transplantation. 8:1729-1736
Thymus transplantation shows promise for the treatment of athymia in complete DiGeorge anomaly. This report reviews the effects of dose of thymus tissue, ABO compatibility, HLA matching, culture conditions, age of donor and immunosuppression of recip
Autor:
Henry E. Rice, Yi-Ju Li, M. Louise Markert, Jeffrey C. Hoehner, Michael A. Skinner, Laura P. Hale, Jie Li, Blythe H. Devlin
Publikováno v:
The Journal of Immunology. 180:6354-6364
Thymus allograft biopsies were performed in athymic infants with complete DiGeorge anomaly after thymus transplantation to assess whether the thymus allograft tissue was able to support thymopoiesis. Forty-four consecutive infants were treated with p
Publikováno v:
Clinical Immunology. 126:277-281
Thymus transplantation in subjects with complete DiGeorge anomaly using postnatal allogeneic HLA-nonmatched cultured thymus tissue provides immunoreconstitution. Tolerance of the newly developed T cells toward the donor thymus has not previously been
Publikováno v:
Seminars in Immunology. 19:297-309
The thymus is essential for proper development and maintenance of a broad T cell repertoire capable of recognizing a wide-range of foreign antigens. Recent advances in multicolor flow cytometry, non-invasive imaging techniques, and molecular assessme
Autor:
Michael A. Skinner, Thomas B. Kepler, Ivan K. Chinn, Elizabeth A. McCarthy, Marilyn J. Alexieff, Min He, Laura P. Hale, M. Louise Markert, Jie Li, Marcella Sarzotti, Blythe H. Devlin, Stephanie E. Gupton, Jeffrey C. Hoehner, Henry E. Rice
Publikováno v:
Blood. 109:4539-4547
The purpose of this study was to characterize a large group of infants with complete DiGeorge anomaly and to evaluate the ability of thymus transplantation to reconstitute immune function in these infants. DiGeorge anomaly is characterized by varying
Autor:
Min He, Marcella Sarzotti, John K. Tomfohr, Blythe H. Devlin, M. Louise Markert, Thomas B. Kepler
Publikováno v:
Bioinformatics. 21:3394-3400
Motivation: The effectiveness of vertebrate adaptive immunity depends crucially on the establishment and maintenance of extreme diversity in the antigen receptor repertoire. Spectratype analysis is a method used in clinical and basic immunological se
Autor:
Thomas B. Kepler, John K. Tomfohr, M. Louise Markert, Min He, Blythe H. Devlin, Marcella Sarzotti
Publikováno v:
Bioinformatics. 21:3697-3699
Summary: SpA is a web-accessible system for the management, visualization and statistical analysis of T-cell receptor spectratype data. Users upload data from their spectratype analyzers to SpA, which saves the raw data and user-defined supplementary