Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Blythe D. Shepard"'
Autor:
Abdullah Aljaylani, Maurice Fluitt, Alexandra Piselli, Blythe D. Shepard, Swasti Tiwari, Carolyn M. Ecelbarger
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 4, Pp 682-695 (2020)
Externí odkaz:
https://doaj.org/article/2ab535906d274b9e83fd46501363b79a
Publikováno v:
Physiological Reports, Vol 9, Iss 23, Pp n/a-n/a (2021)
Abstract Renal olfactory receptor 1393 (Olfr1393) is an understudied sensory receptor that contributes to glucose handling in the proximal tubule. Our previous studies have indicated that this receptor may serve as a regulator of the sodium glucose c
Externí odkaz:
https://doaj.org/article/276e04cce46d41ba8b39498324e0108b
Autor:
Surabhi Bangarbale, Blythe D. Shepard, Shivani Bansal, Meth M. Jayatilake, Ryan Kurtz, Moshe Levi, Carolyn M. Ecelbarger
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1176 (2022)
Sodium glucose cotransporter, type 2 inhibitors, such as Empagliflozin, are protective of the kidneys by unclear mechanisms. Our aim was to determine how Empagliflozin affected kidney cortical metabolome and lipidome in mice. Adult male TALLYHO mice
Externí odkaz:
https://doaj.org/article/ebc3df4bd15947cab1cf34334de3f425
Autor:
Ryan Kurtz, Andrew Libby, Bryce A. Jones, Komuraiah Myakala, Xiaoxin Wang, Yichien Lee, Grace Knoer, Julia N. Lo Cascio, Michaela McCormack, Grace Nguyen, Elijah N. D. Choos, Olga Rodriguez, Avi Z. Rosenberg, Suman Ranjit, Christopher Albanese, Moshe Levi, Carolyn M. Ecelbarger, Blythe D. Shepard
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5675 (2022)
Sodium-glucose co-transporters (SGLTs) serve to reabsorb glucose in the kidney. Recently, these transporters, mainly SGLT2, have emerged as new therapeutic targets for patients with diabetes and kidney disease; by inhibiting glucose reabsorption, the
Externí odkaz:
https://doaj.org/article/45aac6c82d6044bda5aa3b3f6099070a
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Sensory receptors, including olfactory receptors (ORs), taste receptors (TRs), and opsins (Opns) have recently been found in a variety of non-sensory tissues where they have distinct physiological functions. As G protein-coupled receptors (GPCRs), th
Externí odkaz:
https://doaj.org/article/ad7000f7c69a425fa78900e56122bc2f
Publikováno v:
American journal of physiology. Cell physiology. 323(3)
Renal blood flow represents >20% of total cardiac output and with this comes the great responsibility of maintaining homeostasis through the intricate regulation of solute handling. Through the processes of filtration, reabsorption, and secretion, th
Publikováno v:
Seminars in Nephrology. 41:331-348
Diabetes is a worldwide epidemic that is increasing rapidly to become the seventh leading cause of death in the world. The increased incidence of this disease mirrors a similar uptick in obesity and metabolic syndrome, and, collectively, these condit
Publikováno v:
The FASEB Journal. 36
Autor:
Ryan Kurtz, Blythe D. Shepard
Publikováno v:
The FASEB Journal. 36
Autor:
Zahraa S. Hotait, Blythe D. Shepard
Publikováno v:
The FASEB Journal. 36