Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Blythe B., Holmes"'
Publikováno v:
In Japanese Journal of Pharmacology 1999 79(2):141-149
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. 224:93-101
Heroin produced antinociception in the tail flick test through mu receptors in the brain of ICR and CD-1 mice, a response inhibited by 3-O-methylnaltrexone. Tolerance to morphine was produced by subcutaneous morphine pellet implantation. By the third
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f04e587d55f2304f0864aab838cfed85
https://doi.org/10.1111/j.1525-1373.2000.22406.x
https://doi.org/10.1111/j.1525-1373.2000.22406.x
Autor:
Bhavani Sangras, R. V. Krishna Kishore, V. Raj Gopal, Blythe B. Holmes, Wenqi Yang, John R. Falck, Xiu Yu Yi, William B. Campbell
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 321:1023-1031
Epoxyeicosatrienoic acids (EETs) are cytochrome P450 epoxygenase metabolites of arachidonic acid. EETs mediate numerous biological functions. In coronary arteries, they regulate vascular tone by the activation of smooth muscle large-conductance, calc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92c7e3da4a8c70cf3f5bc4d5b489843
https://doi.org/10.1124/jpet.107.119651
https://doi.org/10.1124/jpet.107.119651
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 290:H37-H45
ACh stimulates arachidonic acid (AA) release from membrane phospholipids of vascular endothelial cells (ECs). In rabbit aorta, AA is metabolized through the 15-lipoxygenase pathway to form vasodilatory eicosanoids 15-hydroxy-11,12-epoxyeicosatrienoic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6364d04fb6a8404e3c49e5432f2321
https://doi.org/10.1152/ajpheart.00491.2005
https://doi.org/10.1152/ajpheart.00491.2005
Autor:
Cecilia J. Hillard, Blythe B. Holmes, Michael J. McCoy, William B. Campbell, Kasem Nithipatikom
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 287:E820-E827
Acute nitric oxide (NO) inhibits angiotensin II (ANG II)-stimulated aldosterone synthesis in zona glomerulosa (ZG) cells. In this study, we investigated the effects of chronic administration of NO on the ANG II receptor type 1 (AT1) expression and al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3fcd166f5958c972f8b00280891d9e6
https://doi.org/10.1152/ajpendo.00183.2004
https://doi.org/10.1152/ajpendo.00183.2004
Autor:
Blythe B. Holmes, John R. Falck, David R. Harder, Andrew J. Grall, William B. Campbell, Kasem Nithipatikom
Publikováno v:
Analytical Biochemistry. 298:327-336
Arachidonic acid (AA) can be metabolized by cytochrome P450 (CYP) enzymes to many biologically active compounds including 5,6-, 8,9-, 11,12-, and 14,15-epoxyeicosatrienoic acids (EETs), their corresponding dihydroxyeicosatrienoic acids (DHETs), and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6046a03ec6991c4e1afb3723d10381
https://doi.org/10.1006/abio.2001.5395
https://doi.org/10.1006/abio.2001.5395
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. 220:178-183
Previous work indicates that the antianalgesic action of pentobarbital and neurotensin administered intracerebroventricularly in mice arises from activation of a descending system to release cholecystokinin (CCK) in the spinal cord where CCK is known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d9a0ca7bec04cd8573e813a2a1334c
https://doi.org/10.1046/j.1525-1373.1999.d01-26.x
https://doi.org/10.1046/j.1525-1373.1999.d01-26.x
Publikováno v:
Japanese Journal of Pharmacology. 79:141-149
Intracerebral injection of neurotensin into specific brain loci in rats produces hyperalgesia due to the release of cholecystokinin (CCK) in the spinal cord. The present purpose was to show in another species that neurotensin can antagonize the antin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00303ebe3e7b111733cf4cfaa71f70d
https://doi.org/10.1254/jjp.79.141
https://doi.org/10.1254/jjp.79.141
Publikováno v:
Experimental Biology and Medicine. 218:334-340
Heroin, like morphine, given intracerebroventricularly produces analgesia by acting on mu opioid receptors in most mice. In contrast, in Swiss Webster mice, heroin has the unusual property of acting on brain delta opioid receptors whereas morphine st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a599c3dc092716ff549a6bb6e37909fa
https://doi.org/10.3181/00379727-218-44301
https://doi.org/10.3181/00379727-218-44301
Publikováno v:
Pharmacology Biochemistry and Behavior. 60:245-254
DynorphinA (Dyn) administered intrathecally or released spinally in mice produces antianalgesia, that is, antagonizes morphine analgesia (tail-flick test). Spinal transection eliminates this Dyn antianalgesia. Present results in mice show that intrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454927e6815ea3b6fa5e7c9ffb07c9fa
https://doi.org/10.1016/s0091-3057(97)00578-9
https://doi.org/10.1016/s0091-3057(97)00578-9