Functional human iPSC-derived alveolar-like cells cultured in a miniaturized 96‑Transwell air–liquid interface model.

Autor: Bluhmki, Teresa¹ teresa.bluhmki@boehringer-ingelheim.com, Traub, Stefanie², Müller, Ann-Kathrin², Bitzer, Sarah¹, Schruf, Eva³, Bammert, Marie-Therese³, Leist, Marcel⁴, Gantner, Florian⁵, Garnett, James P³, Heilker, Ralf¹

Publikováno v: Scientific Reports. 8/23/2021, Vol. 11 Issue 1, p1-19. 19p.

Generation of stem cell derived human lung epithelium in High-Throughput-Screenings

Autor: Bluhmki, Teresa

In drug discovery, there is an increasing demand for more physiological in vitro models that recapitulate the disease situation in patients. Many different preclinical approaches to model lung diseases have been established over the years, but they l

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Differentiation of hiPS Cells into Definitive Endoderm for High-Throughput Screening.

Autor: Bluhmki T; Drug Discovery Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany., Traub S; Trenzyme GmbH, Konstanz, Germany., Schruf E; Immunology & Respiratory Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany., Garnett J; Immunology & Respiratory Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany., Gantner F; Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany., Bischoff D; Drug Discovery Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany., Heilker R; Drug Discovery Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany. ralf.heilker@boehringer-ingelheim.com.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2019; Vol. 1994, pp. 101-115.