Zobrazeno 1 - 10
of 267
pro vyhledávání: '"Blood-brain barrier opening"'
Autor:
Antoine Presset, Sylvie Bodard, Antoine Lefèvre, Anaïs Millet, Edward Oujagir, Camille Dupuy, Tarik Iazourène, Ayache Bouakaz, Patrick Emond, Jean-Michel Escoffre, Lydie Nadal-Desbarats
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Microbubble (MB)-assisted ultrasound (US) is an innovative modality for the non-invasive, targeted, and efficient delivery of therapeutic molecules into the brain. Previously, we reported the first metabolomic signature of blood–brain barrier openi
Externí odkaz:
https://doaj.org/article/5c7f09dbd46b43ff9c3b34697ff9cf0c
Autor:
Payton J. Martinez, Jane J. Song, Francis G. Garay, Kang-Ho Song, Toni Mufford, Jenna Steiner, John DeSisto, Nicholas Ellens, Natalie J. Serkova, Adam L. Green, Mark Borden
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Microbubbles (MBs) combined with focused ultrasound (FUS) has emerged as a promising noninvasive technique to permeabilize the blood–brain barrier (BBB) for drug delivery into the brain. However, the safety and biological consequences of B
Externí odkaz:
https://doaj.org/article/76f1eee73d994c8498282e6b889d7fd8
Autor:
Masih Tazhibi, Nicholas McQuillan, Hong-Jian Wei, Matthew Gallitto, Ethan Bendau, Andrea Webster Carrion, Xander Berg, Danae Kokossis, Xu Zhang, Zhiguo Zhang, Chia-Ing Jan, Akiva Mintz, Robyn D. Gartrell, Hasan R. Syed, Adriana Fonseca, Jovana Pavisic, Luca Szalontay, Elisa E. Konofagou, Stergios Zacharoulis, Cheng-Chia Wu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Diffuse midline glioma (DMG) is a pediatric tumor with dismal prognosis. Systemic strategies have been unsuccessful and radiotherapy (RT) remains the standard-of-care. A central impediment to treatment is the blood–brain barrier
Externí odkaz:
https://doaj.org/article/159f8aa414984404a35643a5ecfeb319
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Wound healing of the central nervous system (CNS) is characterized by the classical phases of ‘hemostasis’, ‘inflammation’, ‘proliferation’, and ‘remodeling’. Uncontrolled wound healing results in pathological scar formation hindering
Externí odkaz:
https://doaj.org/article/5ae4e14ec061403d8f54731cf094da43
Autor:
Chih-Yen Chien, Lu Xu, Jinyun Yuan, Siaka Fadera, Andrew H. Stark, Umeshkumar Athiraman, Eric C. Leuthardt, Hong Chen
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105066- (2024)
Summary: Background: Focused ultrasound (FUS) combined with microbubbles is a promising technique for noninvasive, reversible, and spatially targeted blood-brain barrier opening, with clinical trials currently ongoing. Despite the fast development of
Externí odkaz:
https://doaj.org/article/9692771f9e4b47efa57722b61bdfe9b9
Autor:
Dong Liu, Fabian Munoz, Soroosh Sanatkhani, Antonios N. Pouliopoulos, Elisa E. Konofagou, Jack Grinband, Vincent P. Ferrera
Publikováno v:
Brain Stimulation, Vol 16, Iss 4, Pp 1196-1204 (2023)
Background: Focused ultrasound (FUS) is a non-invasive neuromodulation technology that is being investigated for potential treatment of neurological and psychiatric disorders. FUS combined with microbubbles can temporarily open the intact blood-brain
Externí odkaz:
https://doaj.org/article/db89d3f2e07148d3ba70d7cad55d39b3
Autor:
Rashi I. Mehta, Jeffrey S. Carpenter, Rupal I. Mehta, Marc W. Haut, Peng Wang, Manish Ranjan, Umer Najib, Pierre-François D’Haese, Ali R. Rezai
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-16 (2023)
Abstract Background Focused ultrasound (FUS)-mediated blood–brain barrier (BBB) opening is under investigation as a therapeutic modality for neurodegeneration, yet its effects in humans are incompletely understood. Here, we assessed physiologic res
Externí odkaz:
https://doaj.org/article/62bab28d64044f869d53016fbd3cd2c0
Autor:
Bernie S. Owusu-Yaw, Yongzhi Zhang, Lilyan Garrett, Alvin Yao, Kai Shing, Ana Rita Batista, Miguel Sena-Esteves, Jaymin Upadhyay, Kimberly Kegel-Gleason, Nick Todd
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 710 (2024)
Huntington’s disease (HD) is a monogenic neurodegenerative disorder caused by a cytosine–adenine–guanine (CAG) trinucleotide repeat expansion in the HTT gene. There are no cures for HD, but the genetic basis of this disorder makes gene therapy
Externí odkaz:
https://doaj.org/article/43d0c465e7be489286ab7330c5da1dca
Autor:
Mengmeng Zhou, Xuanhao Fu, Boyuan Ma, Ziyu Chen, Yuelin Cheng, Linyan Liu, Shunli Kan, Xinyan Zhao, Sa Feng, Zehua Jiang, Rusen Zhu
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Due to the complex pathological mechanisms of Alzheimer's disease (AD), its treatment remains a challenge. One of the major difficulties in treating AD is the difficulty for drugs to cross the blood–brain barrier (BBB). Low-intensity ultrasound (LI
Externí odkaz:
https://doaj.org/article/1a2d7e48b51e46e3b62646c05fc9001d
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.