Zobrazeno 1 - 10
of 368
pro vyhledávání: '"Blood islands"'
Publikováno v:
Developmental Dynamics. 250:1410-1419
Background In avian species, primordial germ cells (PGCs) migrate to the gonadal primordium through the vascular system. Because this mode of migration is reminiscent of cancer metastasis, it would be useful to elucidate the mechanisms underlying PGC
Publikováno v:
Biology Open, Vol 2, Iss 6, Pp 587-595 (2013)
Summary PTEN is a tumor suppressor gene that is mutated and/or deleted in many types of tumor. This gene also plays a very distinct role in the early stages of embryonic development such as cell migration, proliferation and migration. Nevertheless, l
Externí odkaz:
https://doaj.org/article/6a65a04b251744ce8bcf71456490fbda
Publikováno v:
Journal of Comparative Neurology. 529:340-366
Vascular structures in the developing brain are thought to form via angiogenesis from preformed blood vessels in the cephalic mesenchyme. Immunohistochemical studies of developing mouse brain from E10.5 to E13.5 revealed the presence of avascular blo
Autor:
Danny Jonigk, Tomas Pieler, Juliane Melchert, Kristine A. Henningfeld, Sven Richts, Thomas Lingner
Publikováno v:
Developmental Biology. 459:138-148
The hormone Erythroferrone (ERFE) is a member of the C1q/TNF-related protein family that regulates iron homeostasis through the suppression of hamp. In a gain of function screen in Xenopus embryos, we identified ERFE as a potent secondary axis-induci
Publikováno v:
Developmental Dynamics. 249:636-645
BACKGROUND Vasculature is formed by responding to homeostatic tissue demands including in developing hearts. Hypoxia generally stimulates vascular formation in which vascular endothelial growth factor A (VEGF-A) plays a critical role. Gestational hyp
Autor:
Amanda D Yzaguirre, Arun Padmanabhan, Eric D de Groh, Kurt A Engleka, Jun Li, Nancy A Speck, Jonathan A Epstein
Publikováno v:
eLife, Vol 4 (2015)
Type I neurofibromatosis (NF1) is caused by mutations in the NF1 gene encoding neurofibromin. Neurofibromin exhibits Ras GTPase activating protein (Ras-GAP) activity that is thought to mediate cellular functions relevant to disease phenotypes. Loss o
Externí odkaz:
https://doaj.org/article/27d46286b9ea495bb6740aa413f93f2b
Autor:
Pal Singh S, Wallis Nahaboo, Daniel Monteyne, Marjorie Vermeersch, Schwarz N, David Perez-Morga, Magin Tm, Zwijsen A, Isabelle Migeotte, Bechara Saykali, Eski Se
SUMMARYAfter implantation, the mouse embryo undergoes gastrulation and forms mesoderm and endoderm. Mesoderm participates in embryonic and extra-embryonic tissues including the amnion, yolk sac, chorion and allantois, the umbilical cord precursor.Ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6769a3189c8a9bebef896b47fdeed1de
https://doi.org/10.1101/2021.04.07.438772
https://doi.org/10.1101/2021.04.07.438772
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology
FUNDING This work was supported by the FCT – Fundação para a Ciência e a Tecnologia, I.P. (PTDC/BTM-SAL/29377/2017) and iNOVA4Health (UID/Multi/04462/2019). The Advanced Imaging Facility of the Instituto Gulbenkian de Ciência was supported by n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c8a5b9d4289ed5b2cf3c1b1f912403
Autor:
Jianan Y. Qu, Sicong He, Xuesong Li, Yi Wu, Kani Chen, Yingzhu He, Jin Xu, Zilong Wen, Qiqi Sun, Xinwei Shen, Shachuan Feng, Ye Tian
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Heterogeneity broadly exists in various cell types both during development and at homeostasis. Investigating heterogeneity is crucial for comprehensively understanding the complexity of ontogeny, dynamics, and function of specific cell types. Traditi
Autor:
Guang Wang, Bin-zhen Chen, Lin-rui Gao, Chaojie Wang, Xuesong Yang, Manli Chuai, Yongping Bao, Jing Zhang
Publikováno v:
Reproductive Toxicology. 73:96-104
Ethanol’s effect on embryonic vasculogenesis and its underlying mechanism is obscure. Using VE-cadherin in situ hybridization, we found blood islands formation was inhibited in area opaca, but abnormal VE-cadherin+ cells were seen in area pellucida