Zobrazeno 1 - 10
of 2 180
pro vyhledávání: '"Blood concentration"'
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-10 (2024)
Abstract Background Although the correlation between liver toxicity and vancomycin is generally considered low, it has been observed that the use of vancomycin can lead to abnormal liver function indicators, such as elevated aspartate aminotransferas
Externí odkaz:
https://doaj.org/article/da599c68685e4ef4a6046095e344fc6c
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract In the absence of evidence-based guidance on the impact of hydroxychloroquine (HCQ) blood concentration on efficacy and ocular toxicity in systemic lupus erythematosus (SLE), the clinical monitoring of HCQ blood concentration is not yet wide
Externí odkaz:
https://doaj.org/article/2b354c013b544b07962e31a581fd3879
Autor:
Yasuyuki Kinjo, Eiji Shibata, David J. Askew, Rie Tanaka, Reiko Suga, Masayuki Shimono, Toshihide Sakuragi, Seiichi Morokuma, Masanobu Ogawa, Masafumi Sanefuji, Norio Hamada, Masayuki Ochiai, Shouichi Ohga, Mayumi Tsuji, Koichi Kusuhara, Kiyoshi Yoshino
Publikováno v:
Environment International, Vol 188, Iss , Pp 108725- (2024)
Background: Lifelong health is dependent on prenatal growth and development, influenced by the placental intrauterine environment. Charged with dual functions––exchange of oxygen and nutrients as well as a barrier against toxins––the placenta
Externí odkaz:
https://doaj.org/article/3fc36437d3f04a9fba0c36afb8a5bd07
Autor:
Jing-Yu Zhang, Ling-Chen Ye, Yu-bo Liu, Xiao Yu, Xiang-Xin Zhang, Guang-Xiang Chen, Ren-Jie Xu
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-7 (2024)
Abstract Background A novel approach known as intraosseous regional administration (IORA) has emerged as a technique for delivering prophylactic antibiotics, and it results in higher tissue concentrations around the knee. It is hypothesized that IORA
Externí odkaz:
https://doaj.org/article/cedd90ab86f2421290859d20ce3e00db
Autor:
Jessica E. Wijngaarden, Amina Ahbari, Johanna E. E. Pouw, Henri N. J. M. Greuter, Idris Bahce, Gerben J. C. Zwezerijnen, Daniëlle J. Vugts, Guus A. M. S. van Dongen, Ronald Boellaard, C. Willemien Menke-van der Houven van Oordt, Marc C. Huisman
Publikováno v:
EJNMMI Physics, Vol 11, Iss 1, Pp 1-9 (2024)
Abstract Background PET scans using zirconium-89 labelled monoclonal antibodies (89Zr-mAbs), known as 89Zr-immuno-PET, are made to measure uptake in tumour and organ tissue. Uptake is related to the supply of 89Zr-mAbs in the blood. Measuring activit
Externí odkaz:
https://doaj.org/article/94a232ec570a4e688f5d66db698daa4a
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30393- (2024)
Hydroxychloroquine (HCQ) has gained significant attention as a therapeutic option for systemic lupus erythematosus (SLE) because of its multifaceted mechanism of action. It is a lipophilic, lysosomotropic drug, that easily traverses cell membranes an
Externí odkaz:
https://doaj.org/article/f889b0d508db462fbcdabeb2f7ab69e3
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 6, Pp 1597-1607 (2023)
Abstract Introduction The aim of this study was to determine the factors associated with the concentrations of hydroxychloroquine (HCQ) and its major metabolite, desethylhydroxychloroquine (DHCQ), in patients with systemic lupus erythematosus (SLE).
Externí odkaz:
https://doaj.org/article/da039e18ed6a431a85d6c7abcd665c43
Publikováno v:
Рациональная фармакотерапия в кардиологии, Vol 19, Iss 3, Pp 290-297 (2023)
The article is devoted to the discussion of modern approaches to the use of laboratory methods to improve the tactics of using direct oral anticoagulants (DOACs) therapy. Clinical situations in which it may be reasonable to use data on the blood conc
Externí odkaz:
https://doaj.org/article/ffc81079899a493d8bd1f3463fd6c404
Autor:
Shigeaki Katsumi, Takuya Araki, Hideaki Yashima, Yoshiyuki Miyazawa, Kazuhiro Suzuki, Koujirou Yamamoto
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 497-503 (2023)
We encountered a case in which the general condition of a patient receiving cabazitaxel worsened with concomitant use of clarithromycin. Cabazitaxel is metabolized mainly by CYP3A4, and the frequency of adverse events is known to increase with increa
Externí odkaz:
https://doaj.org/article/701b7126388c4c65a12ee46bcf8c0fa9
Publikováno v:
Archives of Public Health, Vol 81, Iss 1, Pp 1-7 (2023)
Abstract Background The study aims to explore the association between cigarette smoking with blood exposure to volatile organic compounds using population data from the National Health and Nutrition Examination Survey (NHANES) 2017–2018. Methods Ba
Externí odkaz:
https://doaj.org/article/e8f3a4c3712c425c97b3f6d5d45fd026