Zobrazeno 1 - 10 of 49 pro vyhledávání: '"Blood Platelets/drug effects"'
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Sodium-glucose cotransporter 2 inhibitors antagonize lipotoxicity in human myeloid angiogenic cells and ADP-dependent activation in human platelets: potential relevance to prevention of cardiovascular events
Autor: Cecilia Carubbi, Elena Masselli, Riccardo R.C. Bonadonna, Giuliana Gobbi, Anna Solini, Alessandra Dei Cas, Giulia Pozzi, Valentina Spigoni, Federica Fantuzzi
Publikováno v: Cardiovascular Diabetology
Cardiovascular diabetology, 19 (1
Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-15 (2020)
The clear evidence of cardiovascular benefits in cardiovascular outcome trials of sodium-glucose cotransporter 2 inhibitors (SGLT2i) in type 2 diabetes might suggest an effect on atherosclerotic plaque vulnerability and/or thrombosis, in which myeloi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1d2ff06039e7052bef6fbb6960c97d
http://europepmc.org/articles/PMC7140327
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2
Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium
Autor: Jae-Gook Shin, Dan M. Roden, Stefan Winter, Paul A. Gurbel, Michiaki Kubo, Braxton D. Mitchell, Joshua P. Lewis, Yuki Bradford, Daniel Aradi, Kevin P. Bliden, Jurriën M. ten Berg, Thomas O. Bergmeijer, Kiyuk Chang, Ruth E. Pakyz, Alan R. Shuldiner, Ho-Sook Kim, Jean-Luc Reny, Meinrad Gawaz, Tobias Geisler, Gianluca Campo, Marco Valgimigli, Elke Schaeffeler, Jolanta M. Siller-Matula, Gian Franco Gensini, Lene Holmvang, Willibald Hochholzer, Rossella Marcucci, Betti Giusti, Ming Ta Michael Lee, Jean-Pierre Déry, Dietmar Trenk, Ming-Shien Wen, John M. Wallace, Marylyn D. Ritchie, Teri E. Klein, Israel Fernandez-Cadenas, Dimitrios Alexopoulos, Matthias Schwab, Ryan Whaley, John H. Cleator, Pierre Fontana, Joshua D. Backman, Russ B. Altman, Shefali S. Verma, Eun Young Kim, Nadia Paarup Dridi, Li Gong, Joan Montaner
Publikováno v: Clinical Pharmacology & Therapeutics
Clinical Pharmacology and Therapeutics
Verma, S S, Bergmeijer, T O, Gong, L, Reny, J L, Lewis, J P, Mitchell, B D, Alexopoulos, D, Aradi, D, Altman, R B, Bliden, K, Bradford, Y, Campo, G, Chang, K, Cleator, J H, Déry, J P, Dridi, N P, Fernandez-Cadenas, I, Fontana, P, Gawaz, M, Geisler, T, Gensini, G F, Giusti, B, Gurbel, P A, Hochholzer, W, Holmvang, L, Kim, E Y, Kim, H S, Marcucci, R, Montaner, J, Backman, J D, Pakyz, R E, Roden, D M, Schaeffeler, E, Schwab, M, Shin, J G, Siller-Matula, J M, ten Berg, J M, Trenk, D, Valgimigli, M, Wallace, J, Wen, M S, Kubo, M, Lee, M T M, Whaley, R, Winter, S, Klein, T E, Shuldiner, A R, Ritchie, M D & for the ICPC Investigators 2020, ' Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel : A Study by the International Clopidogrel Pharmacogenomics Consortium ', Clinical Pharmacology and Therapeutics, vol. 108, no. 5, pp. 1067-1077 . https://doi.org/10.1002/cpt.1911
Clinical Pharmacology and Therapeutics, Vol. 108, No 5 (2020) pp. 1067-1077
Antiplatelet response to clopidogrel shows wide variation, and poor response is correlated with adverse clinical outcomes. CYP2C19 loss-of-function alleles play an important role in this response, but account for only a small proportion of variabilit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879ba4faf94686e3e39457e594e198cf
http://hdl.handle.net/11392/2437791
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4
Posture changes platelet inhibition time after ingestion of prasugrel
Autor: Antonsen, Jacob, Bundgaard, Nina, Holmvang, Lene, Engstrøm, Thomas, Iversen, Kasper
Publikováno v: Antonsen, J, Bundgaard, N, Holmvang, L, Engstrøm, T & Iversen, K 2018, ' Posture changes platelet inhibition time after ingestion of prasugrel ', Danish Medical Journal, vol. 65, no. 10, A5504 . < http://ugeskriftet.dk/dmj/posture-changes-platelet-inhibition-time-after-ingestion-prasugrel >
INTRODUCTION: Several studies have suggested that supine posture during pill ingestion prolongs oesophageal transit time. Whether ingesting prasugrel in an upright position leads to reduced platelet reactivity during percutaneous coronary interventio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2751::e8a734d298fbbddad15e8c059bdf9d24
https://curis.ku.dk/portal/da/publications/posture-changes-platelet-inhibition-time-after-ingestion-of-prasugrel(650a2c73-03d8-4d54-a01f-89c045cf6edf).html
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5
A Randomized Phase II Trial Investigating the Effect of Platelet Function Inhibition on Circulating Tumor Cells in Patients With Metastatic Breast Cancer
Autor: Catherine Van Poznak, Ryan P. Roop, Timothy J. Pluard, Michael Naughton, Katherine N. Weilbaecher, Farley Johnson, Philip E. Lammers, Jochen G. Schneider, Charles S. Eby
Publikováno v: Clinical breast cancer, 13(6), 409-15. United States (2013).
BACKGROUND: Blockade of platelet activation and aggregation can inhibit metastasis in preclinical models and is associated with cancer prevention. To test whether disruption of platelet function with clopidogrel and aspirin would decrease the number
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a5c816b0f3a01ff6850a58feec3c02
https://doi.org/10.1016/j.clbc.2013.08.006
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6
Consensus and Update on the Definition of On-Treatment Platelet Reactivity to Adenosine Diphosphate Associated With Ischemia and Bleeding
Autor: Laurent Bonello, Young-Hoon Jeong, Ajay J. Kirtane, Daniel Aradi, Nicholas Curzen, Udaya S. Tantry, Dietmar Trenk, Jurriën M. ten Berg, Dirk Sibbing, Jolanta M. Siller-Matula, Sunil V. Rao, Jean-Luc Reny, Dimitrios Alexopoulos, Dominick J. Angiolillo, Ron Waksman, Rossella Marcucci, Matthew J. Price, Elisabeth Mahla, Richard C. Becker, Deepak L. Bhatt, Paul A. Gurbel, Tobias Geisler, Gregg W. Stone
Publikováno v: Journal of the American College of Cardiology, Vol. 62, No 24 (2013) pp. 2261-2273
Dual antiplatelet therapy with aspirin and a P2Y12 receptor blocker is a key strategy to reduce platelet reactivity and to prevent thrombotic events in patients treated with percutaneous coronary intervention. In an earlier consensus document, we pro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0382af09df20ab6f37ac28e51dfaed4
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7
Platelet-derived growth factor enhances platelet recovery in a murine model of radiation-induced thrombocytopenia and reduces apoptosis in megakaryocytes via its receptors and the PI3-k/Akt pathway
Autor: Fanyi Meng, Jian Liang Chen, Liang Qiao, Beng H. Chong, Jieyu Ye, Qizhou Lian, Xue Qun Luo, Ming Ma, Godfrey Chi-Fung Chan, Ruixia Deng, Levon M. Khachigian, Mo Yang
Publikováno v: Haematologica. 95:1745-1753
Background Platelet-derived growth factor is involved in the regulation of hematopoiesis. Imatinib mesylate, a platelet-derived growth factor receptor inhibitor, induces thrombocytopenia in a significant proportion of patients with chronic myeloid le
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4f94669dfaf742a32f1a4d412dd6b7
https://doi.org/10.3324/haematol.2009.020958
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8
Two purified and characterized phospholipases A2 from Cerastes cerastes venom, that inhibit cancerous cell adhesion and migration
Autor: Erwann P. Loret, Olfa Kallech-Ziri, Naziha Marrakchi, Amine Bazaa, Sofiane Bezzine, Najet Srairi-Abid, Aida Karray, José Luis, Raoudha Zouari-Kessentini, Mohamed El Ayeb
Publikováno v: Toxicon
Toxicon, Elsevier, 2009, 53 (4), pp.444-53. ⟨10.1016/j.toxicon.2009.01.003⟩
International audience; Two non-toxic PLA2s were purified to homogeneity from Cerastes cerastes Tunisian snake venom. The purification process employed gel filtration on Sephadex G-75 followed by C18 reverse phase high-pressure liquid chromatography.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1316e6552d2676bd807c7b7dddcd5f46
https://doi.org/10.1016/j.toxicon.2009.01.003
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9
Metabolic energy reduction by glucose deprivation and low gas exchange preserves platelet function after 48 h storage at 4 degrees C
Publikováno v: Vox Sanguinis. 92(4):311-8
INTRODUCTION: We showed earlier that metabolically suppressed platelets (MSP) prepared by incubation in glucose-free, antimycin A medium at 37 degrees C better sustained storage at 4 degrees C than untreated controls at 22 degrees C. However, the use
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___00893::aab5886a1f94459d37071bdb55af2030
https://doi.org/10.1111/j.1423-0410.2007.00891.x
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10
Enteric coating can lead to reduced antiplatelet effect of low-dose acetylsalicylic acid
Autor: Dorte Ejg Jarbøl, Peter Haastrup, Thor Grønlykke
Publikováno v: Fentz Haastrup, P, Grønlykke, T & Jarbøl, D E 2015, ' Enteric coating can lead to reduced antiplatelet effect of low-dose acetylsalicylic acid ', Basic & Clinical Pharmacology & Toxicology, vol. 116, no. 3, pp. 212-215 . https://doi.org/10.1111/bcpt.12362
Low-dose acetylsalicylic acid (ASA) is widely used as antithrombotic prophylaxis. Enteric coated ASA has been developed in order to decrease the risk of gastrointestinal side effects. The consequences of enteric coating on pharmacokinetics and antipl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b4df7c543342acce167ae87a4b9709
https://portal.findresearcher.sdu.dk/da/publications/ca16ddbd-94be-4172-a112-74515093c802
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